Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0262471 (ENT)
 5,307 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This comparative trial of norethindrone enanthate (NET-ENT) and depo-medroxyprogesterone acetate (DMPA) was conducted in a randomized, single blind manner in a clinic in Bangladesh to assess discontinuation rates, reasons for discontinuation, and variablility of side effects between these 2 injectable contraceptives. Of a total of 239 women, 106 received NET-ENT (200 mg) and 133 received DMPA (150 mg). DMPA was given every 12 weeks after the first injection and NET-ENT was given every 10 weeks after initial injection. Oral estrogen therapy was made available to women in this study based on the following criterion: 1) spotting/bleeding lasting more than 7 days; 2) heavy bleeding; or 3) 3 or more months of amenorrhea if this disturbed the subject. For menstrual pattern variability, a larger proportion of women reported irregular bleeding when given NET-ENT than did those with DMPA. On the other hand, on all follow-up visits the proportion of women reporting amenorrhea was higher for DMPA compared with NET-ENT users. However, by the 4th injection, fewer than 15% of clients in both experimental groups still reported regular cyclic bleeding (4 of 26 in DMPA group and 4 of 28 in NET-ENT). 11 pregnancies occurred during treatment, 5 in the DMPA group and 6 in the NET-ENT group. Continuation after 1 year totaled 28 clients, 14 from each group. The primary reasons for discontinuation were pregnancy; medical reasons, including symptoms and fear of symptoms; nonmedical reasons such as desire for more children, or death of husband; or loss to follow-up: the number of clients in the DMPA group discontinuing for these reasons were 5, 48, 17, and 49, respectively, and the respective numbers among NET-ENT users were 6, 34, 24, and 28.
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PMID:A randomized, single blind comparative trial of norethindrone enanthate and depo-medroxyprogesterone acetate in Bangladesh. 644 42

All cases of nasal polyposis seen in a district hospital in Nigeria over a 5 year period were analysed in a prospective study to determine the aetiological pattern, the prevalence, occurrence and pathological types as well as predisposing factors. Out of the 172 patients treated, 144 had common nasal polyps while 28 patients had nasal polyps resulting from tumors. Out of the 144 patients, 103 had inflammatory polyps, 39 were of allergic origin and 2 due to cystic fibrosis. Peak presentation was between 31-40 years with a total of 58 patients (33.72%). All the patients with nasal polyposis represented 0.74% of all attendances to the ENT clinic over the period. There was no sex difference. Nasal polypectomy was carried out in all the patients while Caldwell-Luc's operation and Antrum Washout were carried out on selected cases. There were recurrences in 18 patients over the period. Delay in reporting to the NET clinic was attributed to ignorance on the part of both the patients and the general practitioners who often treated their presenting symptoms as common cold and catarrh.
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PMID:Nasal polyposis in a Nigerian district hospital. 775 90