Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0262471 (ENT)
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Since the introduction of Haemophilus influenza type b (Hib) vaccinations in child immunisation programmes, a significant decline in the incidence of epiglottitis has been observed among children. However, recent studies show an increase in the incidence of adult epiglottitis without any identifiable predominant causative pathogen. Adult disease is known to have a slightly more protracted course. Vigilance is nevertheless indicated due to the risk of a rapidly evolving airway obstruction. In this paper, we discuss three recent cases of adult epiglottitis in a tertiary care unit, and review of the current literature. In two of these cases frank abscess formation was already present at the initial evaluation. In spite of very close monitoring, with securing of the airway, administration of intravenous antibiotics and drainage of the abscess, the eldest patient died. The other patients recovered completely.
B-ENT 2012
PMID:Epiglottitis and related complications in adults. Case reports and review of the literature. 2289 36