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 5,307 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Specific immunotherapy (SIT) is the unique causal treatment for allergy, but its prescription is quite restricted. A perspective and cross-sectional survey based on telephone interviews was carried out in Italy to evaluate the profile of doctors prescribing SIT for allergic rhinitis. A total of 540 doctors were interviewed, 200 of whom are GPs, 60 allergists, 60 ENT specialists, 100 familial paediatricians, 60 hospital paediatricians and 60 pulmonologists. Significant differences concern diagnostic and therapeutic management of allergic rhinitis, mainly regarding SIT prescription. The allergist is the most important consultant who prescribes SIT, as opposed to the paediatrician. This study therefore provides the evidence that doctors behaviour towards SIT depends on the type of graduate studies.
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PMID:Specific immunotherapy for allergic rhinitis in Italy: the doctors points of view. 1930 75

This Supportive Initiative for the Global Management of Allergy (SIGMA) initiative gathered together four multidisciplinary and inter-university groups of Belgian experts in the treatment of allergic rhinitis to review the literature and come to a consensus opinion on the global management of allergy. Their conclusions were as follows. Group 1 concluded that in children suffering from allergic rhinitis, there is sufficient expert opinion in favour of continuous treatment with both H1-antihistamines and corticosteroids for controlling symptoms during periods of allergen exposure, but not to support continuous treatment during periods when symptoms are negligible in an attempt to prevent the development of new allergic diseases. Group 2 came to similar conclusions in adults. Group 3 considered adults with concomitant asthma and stressed the crucial necessity to screen each asthmatic for allergic rhinitis and institute appropriate therapy for both conditions. Even though efficacious treatment algorithms are available for both rhinitis and asthma, an integrated management of these frequently concomitant diseases is not always prescribed even though there is a proven clinical advantage of adequate treatment of the nose of asthmatics. Group 4 concluded that for both H1-antihistamines and nasal corticosteroids, safety data indicate that continuous treatment may be given without fears of adverse consequences. With regard to the cost implications of continuous therapy versus on-demand therapy, there are indications that effective treatment of allergic rhinitis by continuous treatment reduces overall drug costs, particularly that of escape medication and indirect costs in the form of days absent from work and school.
B-ENT 2009
PMID:Treating allergic rhinitis: continuous versus on-demand regime? Executive summary of the Supportive Initiatives for the Global Management of Allergy (SIGMA): report from the Belgian Working Group. 1947 89

The clinical effect of bipolar radiofrequency thermotherapy on allergic rhinitis was evaluated. A bipolar radiofrequency system (CelonLab ENT) was used on 16 patients suffering from allergic rhinitis from February 2003 and August 2003. The thermotherapy was conducted under local anesthesia and data was collected by preoperative questionnaire and rhinomanometry and 2 months and 2 years postoperatively. Nearly all the patients reported relieved nasal patency, rhinorrhea, and sneezeing. Statistically significant improvements were observed for all the measured VAS scores: nasal patency, rhinorrhea, and sneezeing. Nasal resistance measured by anterior rhinomanometry also significantly improved. We concluded that CelonLab ENT is effective and safe in treating allergic rhinitis.
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PMID:[Clinical effect of bipolar radiofrequency thermotherapy on allergic rhinitis]. 1951 98

High prevalence of allergic rhinitis with concomitant ENT abnormalities at the stage of remission or exacerbation was documented among residents of the Rudny Altai region. A total of 200 patients with allergic rhinitis were examined of whom 114 (57%) had concomitant ENT diseases both of allergic and non-allergic origin. Sensitization to the pollen of herbs and grasses was recorded most frequently whereas the contribution of allergic reactions to the pollen of trees and shrubs to overall morbidity was much less significant. Interestingly, very high sensitivity to the pollen of local allergenic flora was documented. Most patients with allergic reactions exhibited poly- and hypersensitization to seasonal allergic rhinitis. Peculiarities of sensitization spectra in patients with allergic rhinitis and concomitant ENT pathology of allergic and non-allergic etiology are discussed.
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PMID:[Allergic rhinitis and concomitant ENT diseases at Rudny Altai]. 2003 48

Olfactory dysfunction is deemed to be a significant contributor to poor quality of life in different nasal inflammatory conditions like common cold, allergic rhinitis, and acute and chronic rhinosinusitis with and without nasal polyps (NP). The mechanism underlying olfactory impairment in inflammatory sinonasal disease relates to either the obstruction of the olfactory cleft due to congestion of the nasal mucosa, the presence of secretions or polyps inside the nasal cavity, or to dysfunction of the sensory mucosa of the olfactory bulb resulting from local inflammation. The reduction of smell capacity in nasal inflammatory conditions may have an acute or gradual onset, often with resolution of smell dysfunction after adequate medical treatment or surgery. In contrast to the well documented effects of surgery for rhinosinusitis on smell dysfunction, the available information about the effects of medical treatment is limited. Most studies have looked at corticosteroids, evaluating the restoration of olfactory capacity as a primary or secondary study outcome parameter. Both nasal and systemic corticosteroids have a beneficial effect on olfactory dysfunction, with systemic treatment being the most powerful. This review aims to provide an overview of current knowledge about medical treatment for rhinosinusitis and its effects on smell.
B-ENT 2009
PMID:Medical therapy and smell dysfunction. 2008 7

The paper summarizes results of a 5 year-long study on the use of a cytological method in clinical practice involving patients with allergic rhinitis and concomitant pathology of ENT organs. The Papanicolaou staining procedure was used for the first time to visualize and measure the content of eosinophils, goblet and mast cells the presence of which suggested local allergy. Eosinophils occurred but rarely (sometimes only 1-2 cells in the field of vision). Cocci, diplococci, and mucous cords were more common. Cytological findings were compared with results of clinical observations. It is concluded that cytological studies are of informative value when used for the study of allergic rhinitis.
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PMID:[Informative value of the cytological method for the study of allergic rhinitis with concomitant pathology of ENT organs]. 2055 50

Extremely high frequency (EHF) therapy (42.19 +/- 0.10 GHz; 5.6 mm) is an efficacious method for the prevention of acute respiratory diseases (ARD) in frequently ill children presenting with chronic ENT diseases (chronic tonsillitis, chronic sinusitis) and allergic reactions (allergic rhinitis, atopic dermatitis). It helped to reduce ARD morbidity, duration of a single ARD episode, and frequency of bacterial complications per one child during the 6 and 12 month-long observation periods in comparison with the patients of the placebo group. It is believed that prophylactic effect of EHF therapy in frequently ill children is due to positive effect of extremely high frequency electromagnetic radiation on the adaptive capacity of the organism, improvement of both cellular and humoral immunity, correction of the initial vegetative tone and vegetative dysfunction.
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PMID:[Extremely high frequency therapy for the prevention of acute respiratory diseases in children with chronic ENT and allergic diseases]. 2133 86

Allergic rhinitis is common worldwide, with significant morbidity and impact on quality of life. In patients who don't respond adequately to anti-allergic drugs. Subcutaneous allergen immunotherapy is effective although requires specialist administration. Sublingual immunotherapy may represent an effective and safer alternative. This Cochrane systematic review is an update of one published in 2003. We searched Cochrane ENT Group Trials Register, Central, PubMed, EMBASE, CINAHL, Web of Science, Biosis Previews, Cambridge Scientific Abstarcts, mRCT and additional sources. We included randomised, double-blind, placebo- controlled trials of sublingual immunotherapy in adults and children. Two authors selected studies and assessed them for quality. Data were put into RevMan 5.0 for a statistical analysis. We used standardised mean difference (SMD), with a random effect model to combine data. Sixty studies were included, with 49 suitable for meta-analysis. We found significant reductions in symptoms (SMD -0.49; 95%CI (-0.64 to -0.34, P < 0.00001)) and medication requirements (SMD -0.32; 95%CI (-0.43 to -0.21, P < 0.00001)) compared with placebo. None of the trials reported severe systemic reactions, anaphylaxis or use of Adrenaline. This updated review reinforces the conclusion of the original 2003 Cochrane Review that sublingual immunotherapy is effective for allergic rhinitis and appears a safe route of administration.
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PMID:Systematic reviews of sublingual immunotherapy (SLIT). 2144 35

Chronic rhinitis (CR) affects large populations worldwide, diagnosed in 40% of the population and is often associated with co-morbidities, such as asthma, sinusitis, rhinoconjunctivitis cognitive dysfunction, and leads to loss of work and school days. Recently, global clinical guidelines were proposed for allergic rhinitis (AR). Similarly, an Israeli expert panel, consisting of ENT and Allergy/Immunology specialists, was delegated to discuss the current approaches to CR (including allergic and non-allergic rhinitis) and to submit a consensus paper. The guidelines, briefly presented herein, describe the epidemiology, mechanisms, diagnostic procedures, treatment modalities and clinical-management algorithms. It is adapted to the Israeli health system and will be distributed to all physicians by the Israel Medical Association. The new clinical guidelines are expected to update current knowledge, improve communication between medical disciplines, provide medico-legal support and improve the management of CR.
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PMID:[Chronic rhinitis--clinical guidelines 2010]. 2157 65

Asthmatic diseases have been reported since the ancient world. Hay fever for instance, was described for the first time in the late 18(th) century, and the term "allergy" was introduced about 100 years ago. Today the incidence of allergies is rising; almost one third of the Western population suffers from its side effects. Allergies are some of the most chronic medical complaints, which results in high health expenditures. Therefore, they have a large health and political relevance.Caused by genetic and environmental factors, the group of IgE mediated allergies is large. It consists of e.g. atopic dermatitis, allergic asthma or allergic rhinitis. This paper aims to emphasize the ways of early diagnosis of allergic rhinitis (AR) as AR represents the most important representative of allergic diseases in ENT.
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PMID:Early detection of allergic diseases in otorhinolaryngology. 2207 91


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