Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0243026 (
sepsis
)
52,417
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
3249
cytokine
3032
lipopolysaccharide
3012
IL-6
1671
LPS
1646
tumor necrosis factor
1564
TNF
1492
Mol
1245
Pseudomonas
1179
IL-10
887
C-reactive protein
840
gut
837
TLR4
814
TNF-alpha
709
She
698
interleukin-6
636
insulin
573
inducible nitric oxide synthase
547
albumin
526
IL-8
504
thrombin
470
nitric oxide synthase
423
myeloperoxidase
418
IL-1
375
tumor necrosis factor alpha
364
fibrinogen
346
CD14
332
protein C
330
CD4
323
granulocyte
321
hemoglobin
321
interferon
319
IFN
312
caspase-3
306
Cytokine
294
tissue factor
294
p38
282
chemokine
280
ATP
278
TLR2
253
prothrombin
244
lymphoid
232
antithrombin
226
superoxide dismutase
223
serum albumin
219
p65
218
CSF
211
interleukin 6
193
MAPK
191
MRI
191
CD11b
189
CRP
184
high mobility group box 1
180
collagen
179
vascular endothelium
179
granulocyte colony-stimulating factor
178
fibronectin
176
chronic renal failure
174
CD8
171
MyD88
168
IFN-gamma
167
glycoprotein
167
muscle protein
167
CLP
165
alanine aminotransferase
160
thrombomodulin
160
Tumor necrosis factor
158
Bcl-2
158
thromboplastin
156
vasopressin
156
catalase
156
MIC
156
IL-1 beta
156
aspartate aminotransferase
155
IL-2
144
interferon-gamma
144
HLA
142
IL-18
142
ICAM-1
141
interleukin-10
141
more...
Disease
sepsis
52417
sepsis
52184
pneumonia
3068
cancer
2488
meningitis
1738
bacteremia
1598
peritonitis
1345
infectious diseases
1283
diabetes
1210
disseminated intravascular coagulation
1094
ischemia
1008
renal failure
944
tumor
919
Infection
841
bacterial infection
839
neutropenia
812
thrombocytopenia
789
endocarditis
758
acute renal failure
744
heart failure
731
respiratory failure
708
adult respiratory distress syndrome
706
Klebsiella
694
stroke
656
hypertension
637
anemia
571
urinary tract infection
559
coagulopathy
553
necrotizing enterocolitis
531
cirrhosis
522
pancreatitis
522
depression
515
malnutrition
446
encephalopathy
444
HIV
440
osteomyelitis
434
liver disease
433
leukemia
410
myocardial infarction
408
renal disease
406
acute pancreatitis
390
lymphoma
387
arthritis
383
rheumatoid arthritis
380
pulmonary edema
374
immunodeficiency
371
carcinoma
364
prematurity
344
tuberculosis
327
AIDS
326
Infections
306
Severe sepsis
305
acute myeloid leukemia
305
hepatitis
302
rash
291
abortion
289
Crohn's disease
288
cholangitis
287
obesity
285
pulmonary hypertension
284
pulmonary embolism
283
cellulitis
282
atherosclerosis
280
congestive heart failure
276
hypoglycemia
275
leukopenia
273
cholestasis
272
cytomegalovirus
269
systemic lupus erythematosus
264
Haemophilus
263
septic arthritis
255
chronic renal failure
255
SIRS
255
fasciitis
253
asthma
251
hyperglycemia
250
coma
249
pyelonephritis
249
chorioamnionitis
249
influenza
248
more...
Symptom
respiratory distress
1354
pain
870
diarrhea
766
anesthesia
600
abdominal pain
445
vomiting
415
hypothermia
288
weakness
284
seizures
268
nausea
193
collapse
185
dyspnea
181
fatigue
157
headache
143
oliguria
139
lethargy
139
cachexia
133
splenomegaly
132
anorexia
131
chills
119
tachypnea
116
starvation
113
hepatosplenomegaly
103
nausea and vomiting
101
cough
99
analgesia
92
hepatomegaly
91
Ill
90
acute abdomen
90
erythema
85
discomfort
75
discomfort
74
chest pain
70
back pain
70
fever of unknown origin
70
exhaustion
63
sore throat
57
constipation
53
cyanosis
53
myalgia
48
hemoptysis
48
regurgitation
47
hypercapnia
46
hyperoxia
46
shortness of breath
43
arthralgia
42
colic
39
hypotonia
37
functional recovery
34
flank pain
34
sleepiness
32
syncope
32
epigastric pain
30
angina
29
pallor
28
acute abdominal pain
27
low back pain
26
rigors
25
paresis
23
hip pain
23
flushing
22
ataxia
22
ENT
22
pelvic pain
22
microbial colonization
21
dizziness
21
polyuria
21
hypoproteinemia
20
dysuria
19
agitation
19
neck pain
18
acute stress
17
bone pain
17
spasticity
17
acidity
17
productive cough
16
overweight
16
asthenia
15
right upper quadrant pain
15
tremor
15
more...
Drug
ampicillin
391
Cardiovasc
369
CSF
260
Dermatol
206
IFN-gamma
164
IL-2
144
Dial
135
Monit
116
G-CSF
103
ROS
100
lysine
96
Nephron
93
ascorbate
92
ROC
90
CTX
77
MAP
68
CTX
63
CTX
63
Drotrecogin alfa
62
Drotrecogin alfa
62
IPM
56
Albumin
54
Bifidobacterium
46
Nephron
46
MOF
43
Heme
41
vitamin E
38
NADH
37
IL-1ra
35
ENT
31
Portal
31
Ringer's solution
30
lactose
30
Indomethacin
28
Ceftazidime
28
p75
27
Piperacillin
27
Simvastatin
25
TAK
24
Antithrombin III
24
Rituximab
23
Meropenem
23
Adriamycin
22
SBT
22
Propofol
21
Nitric Oxide
19
AMC
19
Fraction
19
caffeine
19
Serum albumin
18
Gel
18
Meropenem
18
Colistin
18
CPR
17
nitroglycerin
17
Augmentin
16
Amoxicillin
16
TAT
16
Taxol
16
Augmentin
16
Fluconazole
15
CPZ
15
Asthma
15
Methylprednisolone
15
Ulinastatin
15
Cimetidine
14
Cimetidine
14
AZT
14
Levosimendan
13
Ethanol
13
Growth hormone
13
Growth hormone
13
Tacrolimus
13
MDS
12
Prednisolone
12
IFN-beta
12
Glutathione
12
Aminoguanidine
12
Fluorescein
12
Spectrum
11
more...
Enzyme
APC
672
mitogen-activated protein kinase
506
thrombin
460
peroxidase
454
alanine aminotransferase
326
superoxide dismutase
277
NO synthase
257
aspartate aminotransferase
226
caspase-3
220
ERK
193
catalase
177
thromboplastin
169
protein kinase
166
lactate dehydrogenase
153
beta-lactamase
142
caspase-1
137
alkaline phosphatase
136
focal adhesion kinase
134
proteasome
131
protein kinase C
122
elastase
117
NOS
114
luciferase
105
creatine kinase
101
MIP
98
NADPH oxidase
96
NADPH oxidase
88
plasmin
86
renin
84
neutrophil elastase
82
AMP-activated protein kinase
77
phospholipase A2
75
tissue plasminogen activator
74
ATPase
71
AST
66
glutathione peroxidase
66
kallikrein
66
MAP
65
phosphodiesterase
60
heme oxygenase
57
reverse transcriptase
54
ACS
53
urokinase-type plasminogen activator
52
lysozyme
52
ACE
51
trypsin
50
IKK
49
caspase-11
47
caspase-11
47
collagenase
46
xanthine oxidase
46
phospholipase C
46
guanylate cyclase
46
complex I
46
neuraminidase
43
PARP
41
phosphatidylinositol 3-kinase
41
AMPK
38
calcineurin
37
lipase
36
caspase-8
35
AMPK
35
pyruvate dehydrogenase
34
BMT
33
MEK
32
acetylcholinesterase
31
caspase-9
29
succinate dehydrogenase
28
RNA polymerase
28
GSK
27
CD10
27
phosphoinositide 3-kinase
26
cytochrome oxidase
26
DNase
25
lipoxygenase
25
gamma-glutamyl transpeptidase
25
asparaginase
25
glucose-6-phosphate dehydrogenase
24
myosin light chain kinase
23
lipoprotein lipase
22
more...
Compound
Clin
4413
Dec
3483
oxygen
2023
TNF
1492
nitric oxide
1161
DNA
1031
glucose
932
creatinine
892
water
705
calcium
580
nitrogen
559
sodium
558
urea
455
arginine
421
iron
323
His
320
phosphate
307
Cardiol
286
ATP
278
glutamine
246
CO2
239
tyrosine
218
nitrate
192
galactose
189
sulfate
187
leucine
186
acetate
183
alanine
164
potassium
161
Phe
158
hydrogen
157
MIC
156
serine
139
zinc
138
Dial
135
DIC
134
lysine
133
THP
128
THP
128
ethanol
119
Methicillin
117
cysteine
116
prostacyclin
110
GSH
109
GSH
109
Parenteral
108
silver
102
Vancomycin
99
cAMP
98
iodine
98
Optimal
94
noradrenaline
87
PGE2
82
methionine
80
ADP
80
Insulin
79
NADP
77
ammonia
77
CTX
77
vitamin D
76
salt
75
TOF
74
N-acetylcysteine
74
PEG
72
cGMP
71
Lactate
71
glutamate
69
MAP
67
ADP
67
barium
65
ACTH
64
ADP
64
Glutamine
63
valine
62
tryptophan
61
Melatonin
61
tryptophan
61
glycerol
60
threonine
60
tryptophan
59
more...