Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0243026 (sepsis)
52,417 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 3249
cytokine 3032
lipopolysaccharide 3012
IL-6 1671
LPS 1646
tumor necrosis factor 1564
TNF 1492
Mol 1245
Pseudomonas 1179
IL-10 887
C-reactive protein 840
gut 837
TLR4 814
TNF-alpha 709
She 698
interleukin-6 636
insulin 573
inducible nitric oxide synthase 547
albumin 526
IL-8 504
thrombin 470
nitric oxide synthase 423
myeloperoxidase 418
IL-1 375
tumor necrosis factor alpha 364
fibrinogen 346
CD14 332
protein C 330
CD4 323
granulocyte 321
hemoglobin 321
interferon 319
IFN 312
caspase-3 306
Cytokine 294
tissue factor 294
p38 282
chemokine 280
ATP 278
TLR2 253
prothrombin 244
lymphoid 232
antithrombin 226
superoxide dismutase 223
serum albumin 219
p65 218
CSF 211
interleukin 6 193
MAPK 191
MRI 191
CD11b 189
CRP 184
high mobility group box 1 180
collagen 179
vascular endothelium 179
granulocyte colony-stimulating factor 178
fibronectin 176
chronic renal failure 174
CD8 171
MyD88 168
IFN-gamma 167
glycoprotein 167
muscle protein 167
CLP 165
alanine aminotransferase 160
thrombomodulin 160
Tumor necrosis factor 158
Bcl-2 158
thromboplastin 156
vasopressin 156
catalase 156
MIC 156
IL-1 beta 156
aspartate aminotransferase 155
IL-2 144
interferon-gamma 144
HLA 142
IL-18 142
ICAM-1 141
interleukin-10 141
more...
Disease
sepsis 52417
sepsis 52184
pneumonia 3068
cancer 2488
meningitis 1738
bacteremia 1598
peritonitis 1345
infectious diseases 1283
diabetes 1210
disseminated intravascular coagulation 1094
ischemia 1008
renal failure 944
tumor 919
Infection 841
bacterial infection 839
neutropenia 812
thrombocytopenia 789
endocarditis 758
acute renal failure 744
heart failure 731
respiratory failure 708
adult respiratory distress syndrome 706
Klebsiella 694
stroke 656
hypertension 637
anemia 571
urinary tract infection 559
coagulopathy 553
necrotizing enterocolitis 531
cirrhosis 522
pancreatitis 522
depression 515
malnutrition 446
encephalopathy 444
HIV 440
osteomyelitis 434
liver disease 433
leukemia 410
myocardial infarction 408
renal disease 406
acute pancreatitis 390
lymphoma 387
arthritis 383
rheumatoid arthritis 380
pulmonary edema 374
immunodeficiency 371
carcinoma 364
prematurity 344
tuberculosis 327
AIDS 326
Infections 306
Severe sepsis 305
acute myeloid leukemia 305
hepatitis 302
rash 291
abortion 289
Crohn's disease 288
cholangitis 287
obesity 285
pulmonary hypertension 284
pulmonary embolism 283
cellulitis 282
atherosclerosis 280
congestive heart failure 276
hypoglycemia 275
leukopenia 273
cholestasis 272
cytomegalovirus 269
systemic lupus erythematosus 264
Haemophilus 263
septic arthritis 255
chronic renal failure 255
SIRS 255
fasciitis 253
asthma 251
hyperglycemia 250
coma 249
pyelonephritis 249
chorioamnionitis 249
influenza 248
more...
Symptom
respiratory distress 1354
pain 870
diarrhea 766
anesthesia 600
abdominal pain 445
vomiting 415
hypothermia 288
weakness 284
seizures 268
nausea 193
collapse 185
dyspnea 181
fatigue 157
headache 143
oliguria 139
lethargy 139
cachexia 133
splenomegaly 132
anorexia 131
chills 119
tachypnea 116
starvation 113
hepatosplenomegaly 103
nausea and vomiting 101
cough 99
analgesia 92
hepatomegaly 91
Ill 90
acute abdomen 90
erythema 85
discomfort 75
discomfort 74
chest pain 70
back pain 70
fever of unknown origin 70
exhaustion 63
sore throat 57
constipation 53
cyanosis 53
myalgia 48
hemoptysis 48
regurgitation 47
hypercapnia 46
hyperoxia 46
shortness of breath 43
arthralgia 42
colic 39
hypotonia 37
functional recovery 34
flank pain 34
sleepiness 32
syncope 32
epigastric pain 30
angina 29
pallor 28
acute abdominal pain 27
low back pain 26
rigors 25
paresis 23
hip pain 23
flushing 22
ataxia 22
ENT 22
pelvic pain 22
microbial colonization 21
dizziness 21
polyuria 21
hypoproteinemia 20
dysuria 19
agitation 19
neck pain 18
acute stress 17
bone pain 17
spasticity 17
acidity 17
productive cough 16
overweight 16
asthenia 15
right upper quadrant pain 15
tremor 15
more...
Drug
ampicillin 391
Cardiovasc 369
CSF 260
Dermatol 206
IFN-gamma 164
IL-2 144
Dial 135
Monit 116
G-CSF 103
ROS 100
lysine 96
Nephron 93
ascorbate 92
ROC 90
CTX 77
MAP 68
CTX 63
CTX 63
Drotrecogin alfa 62
Drotrecogin alfa 62
IPM 56
Albumin 54
Bifidobacterium 46
Nephron 46
MOF 43
Heme 41
vitamin E 38
NADH 37
IL-1ra 35
ENT 31
Portal 31
Ringer's solution 30
lactose 30
Indomethacin 28
Ceftazidime 28
p75 27
Piperacillin 27
Simvastatin 25
TAK 24
Antithrombin III 24
Rituximab 23
Meropenem 23
Adriamycin 22
SBT 22
Propofol 21
Nitric Oxide 19
AMC 19
Fraction 19
caffeine 19
Serum albumin 18
Gel 18
Meropenem 18
Colistin 18
CPR 17
nitroglycerin 17
Augmentin 16
Amoxicillin 16
TAT 16
Taxol 16
Augmentin 16
Fluconazole 15
CPZ 15
Asthma 15
Methylprednisolone 15
Ulinastatin 15
Cimetidine 14
Cimetidine 14
AZT 14
Levosimendan 13
Ethanol 13
Growth hormone 13
Growth hormone 13
Tacrolimus 13
MDS 12
Prednisolone 12
IFN-beta 12
Glutathione 12
Aminoguanidine 12
Fluorescein 12
Spectrum 11
more...
Enzyme
APC 672
mitogen-activated protein kinase 506
thrombin 460
peroxidase 454
alanine aminotransferase 326
superoxide dismutase 277
NO synthase 257
aspartate aminotransferase 226
caspase-3 220
ERK 193
catalase 177
thromboplastin 169
protein kinase 166
lactate dehydrogenase 153
beta-lactamase 142
caspase-1 137
alkaline phosphatase 136
focal adhesion kinase 134
proteasome 131
protein kinase C 122
elastase 117
NOS 114
luciferase 105
creatine kinase 101
MIP 98
NADPH oxidase 96
NADPH oxidase 88
plasmin 86
renin 84
neutrophil elastase 82
AMP-activated protein kinase 77
phospholipase A2 75
tissue plasminogen activator 74
ATPase 71
AST 66
glutathione peroxidase 66
kallikrein 66
MAP 65
phosphodiesterase 60
heme oxygenase 57
reverse transcriptase 54
ACS 53
urokinase-type plasminogen activator 52
lysozyme 52
ACE 51
trypsin 50
IKK 49
caspase-11 47
caspase-11 47
collagenase 46
xanthine oxidase 46
phospholipase C 46
guanylate cyclase 46
complex I 46
neuraminidase 43
PARP 41
phosphatidylinositol 3-kinase 41
AMPK 38
calcineurin 37
lipase 36
caspase-8 35
AMPK 35
pyruvate dehydrogenase 34
BMT 33
MEK 32
acetylcholinesterase 31
caspase-9 29
succinate dehydrogenase 28
RNA polymerase 28
GSK 27
CD10 27
phosphoinositide 3-kinase 26
cytochrome oxidase 26
DNase 25
lipoxygenase 25
gamma-glutamyl transpeptidase 25
asparaginase 25
glucose-6-phosphate dehydrogenase 24
myosin light chain kinase 23
lipoprotein lipase 22
more...
Compound
Clin 4413
Dec 3483
oxygen 2023
TNF 1492
nitric oxide 1161
DNA 1031
glucose 932
creatinine 892
water 705
calcium 580
nitrogen 559
sodium 558
urea 455
arginine 421
iron 323
His 320
phosphate 307
Cardiol 286
ATP 278
glutamine 246
CO2 239
tyrosine 218
nitrate 192
galactose 189
sulfate 187
leucine 186
acetate 183
alanine 164
potassium 161
Phe 158
hydrogen 157
MIC 156
serine 139
zinc 138
Dial 135
DIC 134
lysine 133
THP 128
THP 128
ethanol 119
Methicillin 117
cysteine 116
prostacyclin 110
GSH 109
GSH 109
Parenteral 108
silver 102
Vancomycin 99
cAMP 98
iodine 98
Optimal 94
noradrenaline 87
PGE2 82
methionine 80
ADP 80
Insulin 79
NADP 77
ammonia 77
CTX 77
vitamin D 76
salt 75
TOF 74
N-acetylcysteine 74
PEG 72
cGMP 71
Lactate 71
glutamate 69
MAP 67
ADP 67
barium 65
ACTH 64
ADP 64
Glutamine 63
valine 62
tryptophan 61
Melatonin 61
tryptophan 61
glycerol 60
threonine 60
tryptophan 59
more...