Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0243026 (
sepsis
)
52,417
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
3249
cytokine
3032
lipopolysaccharide
3012
IL-6
1671
LPS
1646
tumor necrosis factor
1564
TNF
1492
Mol
1245
Pseudomonas
1179
IL-10
887
C-reactive protein
840
gut
837
TLR4
814
TNF-alpha
709
She
698
interleukin-6
636
insulin
573
inducible nitric oxide synthase
547
albumin
526
IL-8
504
thrombin
470
nitric oxide synthase
423
myeloperoxidase
418
IL-1
375
tumor necrosis factor alpha
364
fibrinogen
346
CD14
332
protein C
330
CD4
323
granulocyte
321
hemoglobin
321
interferon
319
IFN
312
caspase-3
306
Cytokine
294
tissue factor
294
p38
282
chemokine
280
ATP
278
TLR2
253
more...
Disease
sepsis
52417
sepsis
52184
pneumonia
3068
cancer
2488
meningitis
1738
bacteremia
1598
peritonitis
1345
infectious diseases
1283
diabetes
1210
disseminated intravascular coagulation
1094
ischemia
1008
renal failure
944
tumor
919
Infection
841
bacterial infection
839
neutropenia
812
thrombocytopenia
789
endocarditis
758
acute renal failure
744
heart failure
731
respiratory failure
708
adult respiratory distress syndrome
706
Klebsiella
694
stroke
656
hypertension
637
anemia
571
urinary tract infection
559
coagulopathy
553
necrotizing enterocolitis
531
pancreatitis
522
cirrhosis
522
depression
515
malnutrition
446
encephalopathy
444
HIV
440
osteomyelitis
434
liver disease
433
leukemia
410
myocardial infarction
408
renal disease
406
more...
Symptom
respiratory distress
1354
pain
870
diarrhea
766
anesthesia
600
abdominal pain
445
vomiting
415
hypothermia
288
weakness
284
seizures
268
nausea
193
collapse
185
dyspnea
181
fatigue
157
headache
143
oliguria
139
lethargy
139
cachexia
133
splenomegaly
132
anorexia
131
chills
119
tachypnea
116
starvation
113
hepatosplenomegaly
103
nausea and vomiting
101
cough
99
analgesia
92
hepatomegaly
91
acute abdomen
90
Ill
90
erythema
85
discomfort
75
discomfort
74
back pain
70
fever of unknown origin
70
chest pain
70
exhaustion
63
sore throat
57
constipation
53
cyanosis
53
myalgia
48
more...
Drug
ampicillin
391
Cardiovasc
369
CSF
260
Dermatol
206
IFN-gamma
164
IL-2
144
Dial
135
Monit
116
G-CSF
103
ROS
100
lysine
96
Nephron
93
ascorbate
92
ROC
90
CTX
77
MAP
68
CTX
63
CTX
63
Drotrecogin alfa
62
Drotrecogin alfa
62
IPM
56
Albumin
54
Bifidobacterium
46
Nephron
46
MOF
43
Heme
41
vitamin E
38
NADH
37
IL-1ra
35
ENT
31
Portal
31
Ringer's solution
30
lactose
30
Indomethacin
28
Ceftazidime
28
p75
27
Piperacillin
27
Simvastatin
25
TAK
24
Antithrombin III
24
more...
Enzyme
APC
672
mitogen-activated protein kinase
506
thrombin
460
peroxidase
454
alanine aminotransferase
326
superoxide dismutase
277
NO synthase
257
aspartate aminotransferase
226
caspase-3
220
ERK
193
catalase
177
thromboplastin
169
protein kinase
166
lactate dehydrogenase
153
beta-lactamase
142
caspase-1
137
alkaline phosphatase
136
focal adhesion kinase
134
proteasome
131
protein kinase C
122
elastase
117
NOS
114
luciferase
105
creatine kinase
101
MIP
98
NADPH oxidase
96
NADPH oxidase
88
plasmin
86
renin
84
neutrophil elastase
82
AMP-activated protein kinase
77
phospholipase A2
75
tissue plasminogen activator
74
ATPase
71
glutathione peroxidase
66
kallikrein
66
AST
66
MAP
65
phosphodiesterase
60
heme oxygenase
57
more...
Compound
Clin
4413
Dec
3483
oxygen
2023
TNF
1492
nitric oxide
1161
DNA
1031
glucose
932
creatinine
892
water
705
calcium
580
nitrogen
559
sodium
558
urea
455
arginine
421
iron
323
His
320
phosphate
307
Cardiol
286
ATP
278
glutamine
246
CO2
239
tyrosine
218
nitrate
192
galactose
189
sulfate
187
leucine
186
acetate
183
alanine
164
potassium
161
Phe
158
hydrogen
157
MIC
156
serine
139
zinc
138
Dial
135
DIC
134
lysine
133
THP
128
THP
128
ethanol
119
more...