Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0243026 (sepsis)
52,417 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 3249
cytokine 3032
lipopolysaccharide 3012
IL-6 1671
LPS 1646
tumor necrosis factor 1564
TNF 1492
Mol 1245
Pseudomonas 1179
IL-10 887
C-reactive protein 840
gut 837
TLR4 814
TNF-alpha 709
She 698
interleukin-6 636
insulin 573
inducible nitric oxide synthase 547
albumin 526
IL-8 504
thrombin 470
nitric oxide synthase 423
myeloperoxidase 418
IL-1 375
tumor necrosis factor alpha 364
fibrinogen 346
CD14 332
protein C 330
CD4 323
granulocyte 321
hemoglobin 321
interferon 319
IFN 312
caspase-3 306
Cytokine 294
tissue factor 294
p38 282
chemokine 280
ATP 278
TLR2 253
more...
Disease
sepsis 52417
sepsis 52184
pneumonia 3068
cancer 2488
meningitis 1738
bacteremia 1598
peritonitis 1345
infectious diseases 1283
diabetes 1210
disseminated intravascular coagulation 1094
ischemia 1008
renal failure 944
tumor 919
Infection 841
bacterial infection 839
neutropenia 812
thrombocytopenia 789
endocarditis 758
acute renal failure 744
heart failure 731
respiratory failure 708
adult respiratory distress syndrome 706
Klebsiella 694
stroke 656
hypertension 637
anemia 571
urinary tract infection 559
coagulopathy 553
necrotizing enterocolitis 531
pancreatitis 522
cirrhosis 522
depression 515
malnutrition 446
encephalopathy 444
HIV 440
osteomyelitis 434
liver disease 433
leukemia 410
myocardial infarction 408
renal disease 406
more...
Symptom
respiratory distress 1354
pain 870
diarrhea 766
anesthesia 600
abdominal pain 445
vomiting 415
hypothermia 288
weakness 284
seizures 268
nausea 193
collapse 185
dyspnea 181
fatigue 157
headache 143
oliguria 139
lethargy 139
cachexia 133
splenomegaly 132
anorexia 131
chills 119
tachypnea 116
starvation 113
hepatosplenomegaly 103
nausea and vomiting 101
cough 99
analgesia 92
hepatomegaly 91
acute abdomen 90
Ill 90
erythema 85
discomfort 75
discomfort 74
back pain 70
fever of unknown origin 70
chest pain 70
exhaustion 63
sore throat 57
constipation 53
cyanosis 53
myalgia 48
more...
Drug
ampicillin 391
Cardiovasc 369
CSF 260
Dermatol 206
IFN-gamma 164
IL-2 144
Dial 135
Monit 116
G-CSF 103
ROS 100
lysine 96
Nephron 93
ascorbate 92
ROC 90
CTX 77
MAP 68
CTX 63
CTX 63
Drotrecogin alfa 62
Drotrecogin alfa 62
IPM 56
Albumin 54
Bifidobacterium 46
Nephron 46
MOF 43
Heme 41
vitamin E 38
NADH 37
IL-1ra 35
ENT 31
Portal 31
Ringer's solution 30
lactose 30
Indomethacin 28
Ceftazidime 28
p75 27
Piperacillin 27
Simvastatin 25
TAK 24
Antithrombin III 24
more...
Enzyme
APC 672
mitogen-activated protein kinase 506
thrombin 460
peroxidase 454
alanine aminotransferase 326
superoxide dismutase 277
NO synthase 257
aspartate aminotransferase 226
caspase-3 220
ERK 193
catalase 177
thromboplastin 169
protein kinase 166
lactate dehydrogenase 153
beta-lactamase 142
caspase-1 137
alkaline phosphatase 136
focal adhesion kinase 134
proteasome 131
protein kinase C 122
elastase 117
NOS 114
luciferase 105
creatine kinase 101
MIP 98
NADPH oxidase 96
NADPH oxidase 88
plasmin 86
renin 84
neutrophil elastase 82
AMP-activated protein kinase 77
phospholipase A2 75
tissue plasminogen activator 74
ATPase 71
glutathione peroxidase 66
kallikrein 66
AST 66
MAP 65
phosphodiesterase 60
heme oxygenase 57
more...
Compound
Clin 4413
Dec 3483
oxygen 2023
TNF 1492
nitric oxide 1161
DNA 1031
glucose 932
creatinine 892
water 705
calcium 580
nitrogen 559
sodium 558
urea 455
arginine 421
iron 323
His 320
phosphate 307
Cardiol 286
ATP 278
glutamine 246
CO2 239
tyrosine 218
nitrate 192
galactose 189
sulfate 187
leucine 186
acetate 183
alanine 164
potassium 161
Phe 158
hydrogen 157
MIC 156
serine 139
zinc 138
Dial 135
DIC 134
lysine 133
THP 128
THP 128
ethanol 119
more...