Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0243026 (sepsis)
 52,417 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We used gadolinium-enhanced fat-suppressed MRI to investigate 67 patients with persistent pain after lumbar discectomy. Twenty-five patients had reoperations for lesions diagnosed in this way. Eleven were for recurrent disc prolapse at the same level and sciatica was relieved by all but one. Five operations were for prolapse at an adjacent level and all were successful. The diagnosis of sepsis was less precise, but extension of tissue enhancement into the operated disc space was found to be significant. Only three patients had evidence of arachnoiditis which suggests that this condition has been too often diagnosed as a cause of persisting low back pain.
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PMID:High-resolution MRI in the investigation of recurrent pain after lumbar discectomy. 833 Nov 3

Cerebrovascular disease may be secondary to various disorders including hypothyroidism, sepsis, neoplasia, hypertension, vascular malformation, and coagulopathy. Brain infarction or hemorrhage should be suspected in an animal with a sudden onset of a focal brain lesion. The recent availability of CT and MRI has improved our ability to diagnose cerebrovascular disease in animals. Treatment is directed at maintaining adequate oxygenation of the brain, controlling elevations of ICP, treating seizures, and identifying and treating any underlying disease. With appropriate care, many animals can recover.
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PMID:Cerebrovascular disease. 881 57

We report a case of histologically verified melanoma of the nose which presented 2 years after initial radiotherapy with left temporomandibular pain, dysfunction and dental sepsis. Conventional radiography revealed a partially dentate mandible with a destructive lesion involving the left condyle, an ill-defined lesion in the right retromolar region and chronic inflammatory apical root lesions. Since MRI of the nose was done at the initial presentation, it was postulated that MRI could be used to characterize the destructive jaw lesions. The MR features were similar to the original nasal lesion and accepted as proof of diagnosis of metastatic melanoma. A literature review reveals only 37 previous cases of metastasis to the temporomandibular joint with none of involvement by melanoma. The role of MRI in the diagnosis of this lesion is also described for the first time.
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PMID:Case report. Magnetic resonance features of metastatic melanoma of the temporomandibular joint and mandible. 916 Nov 85

Streptococcus agalactiae is a well-recognized cause of neonatal sepsis and meningitis. In adults, infections by S. agalactiae are rare. We report an adult case of lung abscess and pyogenic spondylitis caused by S. agalactiae. A 51-year-old male was admitted to our hospital because of an abnormal shadow in the chest and lumbago on May 25, 1995. He was diagnosed as lung abscess from the chest roentgenogram and CT scan and the subcutaneous pus was aspirated. The pus culture was only positive for S. agalactiae. He was treated with IPM/CS 1 g/day and CLDM 1.2 g/day and the abscess was drained. MRI showed his lumbago was caused by pyogenic spondylitis. The underlying disease of this case was diabetes mellitus. He recovered from the infections with in about 10 weeks of antibiotic treatment.
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PMID:[Case report: lung abscess caused by Streptococcus agalactiae]. 939 64

A 62-year-old man developed clumsiness, vertical ophthalmoplegia, right-side dominant parkinsonism, pyramidal signs, limb-kinetic apraxia and dementia. His brain MRI and SPECT revealed mild fronto-parietal atrophy and hypoperfusion predominately on the right side. At the age of 65, the patient died of sepsis. The duration of his illness was approximately 3 years. Clinical diagnosis was corticobasal degeneration (CBD). On neuropathological examination, there was no neuronal loss and many neurofibrillary tangles (NFTs) in the cerebral cortices. Basal ganglia and substantia nigra showed moderate to severe neuronal loss. And there were many NFTs and argyrophillic threads (threads) in the subthalamic nucleus and nuclei of the brainstem. These findings were almost compatible to those of PSP. However, the following findings were atypical for PSP, 1) mild atrophy and absence of gliosis in the tegmentum of the brain stem, 2) Mild neuronal loss in the subthalamic nucleus and the dentate nucleus without grumose degeneration. Furthermore, characteristic findings were noted on modified Gallyas-Braak stain. Numerous threads and many astrocytic plaques (AP) were shown in cerebral cortices, which were particular to CBD cases. So this case demonstrated neuropathological findings of both PSP and CBD. Therefore, it was difficult to classify this case as either PSP or CBD, and we diagnosed this case as a neuropathological overlapping case of both PSP and CBD.
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PMID:[A case manifested overlapping neuropathologic features of both progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD)]. 956 3

Patients with clinically suspected anorectal sepsis were studied using MRI in order to determine if T2 weighted sequences with fat suppression conveyed any additional benefit over conventional short tau inversion recovery (STIR) sequences. 23 consecutive patients (16 male) undergoing MRI for suspected perianal sepsis were studied prospectively using a 1.0 T whole body system and body coil. Axial and coronal T1 weighted turbo spin echo sequences were obtained, followed by STIR and T2 weighted spectral fat saturation inversion recovery (SPIR) sequences. Images were assessed for the presence of sepsis or fistula, and information provided by the sequences compared. Active disease was diagnosed in 17 patients, 14 of whom had fistula-in-ano; one intersphincteric, 10 transsphincteric and three extrasphincteric. Internal openings were identified in all of these 14 patients; anal in 10, rectal in two, and both in two. Diagnosis and fistula classification was possible in all of these 14 subjects on the basis of STIR sequences alone. The anal sphincters and pelvic floor musculature were better resolved by STIR than SPIR, leading to easier and more confident determination of fistula anatomy in eight of the 14 (57%). In no case did STIR sequences fail to resolve inflammation seen subsequently on SPIR, despite reduced track intensity. T1 weighted sequences were generally non-contributory. Both STIR and SPIR sequences are adequate to classify fistula-in-ano, but classification was easier with STIR due to superior resolution of pelvic floor structures.
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PMID:Magnetic resonance imaging of fistula-in-ano: STIR or SPIR? 957 77

Patients in rest-homes, intensive care units, long hospitalization and dialysis and whoever stays in a hospital continuously or occasionally for long periods of time may run into the well-known and typical complications of prolonged hospitalization. We have studied the urologic aspect in all the cases of the Medical- Surgical Emergency Institute in the Hospital of Ancona (seated in Torrette), over the period 1990-96, in patients hospitalized for at least 30 days. All the patients were followed and studied with the same method, though taking into account their different pathological conditions. They were treated by the same medical and paramedical staff. The same antibiotic therapy and the same checkup were adopted for all of them. We have noticed that out of 122 patients the most frequent pathologies have been urinary infections (19%); while sepsis with different pathogenesis was recorded in 4% of the patients. The method of study applied during and after the hospitalization was used also in rehabilitation centres and included: urologic examination, rectal touch (in men), direct X-ray of the abdomen, ultrasound of the urinary tract, X-ray urography, if required; moreover urodynamic examination, MRI of encephalon and spinal marrow in patients with neurological lesions. The catheter was removed in all the patients and none of the following conditions were observed: vesical lithiasis, abscesses, fistulae in penoscrotal angle, urethrostenosis, injuries to renal emunctory. In conclusion we believe that the functional symptoms of minction--be they of obstructive or irritable nature--are not existent and that the urologic prognosis in long term patients in excellent, provided that prophylaxis is carried on against hospital urinary infections as their occurrence is very frequent and therapy is expensive. It can also be stated the patient hospitalized in ICU will not present damages to the urinary tract, even if he/she has been hospitalized because of injuries to the urinary tract, provided that the urologic tutoring, together with the action of the physician handling the Emergency, follow the rules for asepsis, the best biocompatible materials are use, infections are monitored, the extensions of cerebrospinal injuries are examined and therapeutic axioms, such as barren and clean intermittent catheterism, are finally adopted.
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PMID:[Functional urination disorders in patients recovering in an intensive care unit for more than 30 days]. 970 63

A preterm infant, whose course was complicated by sepsis, necrotizing enterocolitis with jejunal perforation, intraventricular hemorrhage and cerebellar hemorrhage, suffered permanent and total paralysis below the neck from extravasation of parenteral nutrition fluids through a femoral venous catheter. MRI imaging revealed extravasation of fluid into the paraspinus musculature with extension into the spinal canal. This fluid was identified as hyperalimentation and intralipid. Postmortem examination found evidence of necrosis of the spinal cord as well as perforation of the right iliac vein.
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PMID:Case report: total parenteral nutrition extravasation associated with spinal cord compression and necrosis. 1126 71

A 51-year-old woman underwent emergency laparoscopic cholecystectomy. Stone loss occurred during gallbladder dissection. Histology showed empyema of the gallbladder. Postoperatively, she developed a subhepatic abscess that required percutaneous drainage. Two years after surgery, she re-presented with a right paracolic abscess. Transsciatic CT-guided drainage of the abscess was performed. Barium enema excluded colonic pathology. Two weeks later, she developed a right gluteal abscess deep to the recent drain site. Ultrasound-guided drainage was performed followed by a sonogram. The sonogram ruled out communication with the peritoneum. Two further subhepatic abscesses occurred during the next 5 years; the first abscess was drained percutaneously, but the second required open drainage: At laparotomy, gallstone fragments were found within the abscess cavity. The site of the previous gluteal drain continued to discharge intermittently. An MRI scan showed an uncomplicated sinus track. Subsequent sinography of the right gluteal track demonstrated an opacity at the apex of the sinus. The sinus was laid open and a gallstone retrieved. The patient has remained well for 3 years. Complications due to gallstone spillage generally manifest themselves shortly after surgery. This case demonstrates that lost stones may cause chronic abdominal and abdominal wall sepsis. In cases of chronic abdominal sepsis after laparoscopic cholecystectomy, the possibility of lost stones should be considered even if stones are not positively shown on imaging.
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PMID:Recurrent septic episodes following gallstone spillage at laparoscopic cholecystectomy. 1144 30

50 consecutive patients presenting with facial swelling thought clinically to be due to salivary gland disease underwent MRI. Examinations were interpreted by one radiologist without access to previous investigations. Records were reviewed to determine the reliability and role of MRI in patient management, and the contribution of other prior or subsequent investigations. MRI findings were verified against operative findings, percutaneous biopsy or clinical follow-up (periods ranging from 8-58 months). A mass was found in 27 patients; in 11 of these patients, disease was extrinsic to the salivary gland. MRI diagnosis of tumour was correct in all patients and MRI was a reliable investigation for planning surgical resection. No mass was found in 23 patients, 8 of whom had normal appearances. Evidence of salivary duct dilatation was seen in 12 patients and fatty infiltration was seen in 3. MRI findings appeared correct in all patients. Prior investigation was undertaken in 29 patients, including orthopantomography, ultrasound and sialography; none provided additional information. Sialography was carried out in three patients after MRI and concurred with MRI in all cases. MRI was an adequate basis for management in all patients and therefore appears to be an effective first line investigation of facial swelling. It is reasonable for patients to undergo preliminary investigation for dental sepsis, this being the most common cause of facial swelling. Further study is required to determine whether MRI can completely replace invasive sialography.
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PMID:The role of MRI in facial swelling due to presumed salivary gland disease. 1171 83


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