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Query: UMLS:C0243026 (sepsis)
 52,417 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Seven pregnant women with symptomatic hydronephrosis had sonographically guided percutaneous nephrostomy for pyosepsis (five patients) or for pain with azotemia (two patients with renal transplants). Antibiotics had been ineffective in controlling pyosepsis in each patient; retrograde ureteral catheterization via cystoscopy was unsuccessful in one patient. After percutaneous nephrostomy, prompt clinical improvement was observed in all patients (i.e., sepsis was relieved and pain abated). Labor was not induced in any of the patients, and no adverse effects occurred to any fetus or mother. Eleven (eight percutaneous nephrostomy, three catheter exchanges) of the 12 procedures were done without conventional radiography and with sonographic guidance alone. After percutaneous nephrostomy, maneuvers to obtain a diagnosis and to treat the obstruction (if necessary) were delayed until after delivery. The causes of ureteral obstruction were calculi (four patients) and a gravid uterus (three patients). After delivery, stones were removed either percutaneously (one patient) or cystoscopically (two patients) or passed spontaneously (one patient); resolution of obstruction by the gravid uterus was proved by Whitaker test after delivery. Sonographically guided percutaneous nephrostomy is an effective and safe method to treat pregnant women who have symptomatic obstructive hydronephrosis associated with either pyosepsis or azotemia. The procedure is rapid, requires minimal anesthesia, has no radiation, and is safe for the fetus. The technique is a useful and perhaps preferable alternative to more invasive surgical therapy or retrograde stenting.
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PMID:Symptomatic renal obstruction or urosepsis during pregnancy: treatment by sonographically guided percutaneous nephrostomy. 172 66

Physicians admitted a 38-year-old woman to the Stanford University Hospital in Palo Alto, California who had experienced pelvic pressure, suprapubic pain, urinary urgency, and terminal blood in the urine. Microscopic examination showed 15-25 leukocytes and 20-25 red blood cells per high power field in the urine. The culture grew no microorganisms. 16 years prior to admission, the patient had had a Dalkon shield IUD inserted. Yet 13 years prior to admission, she had a pelvic abscess and sepsis after the IUD perforated the uterus. Physicians then performed an emergency hysterectomy and removed both ovaries and Fallopian tubes. She experienced no more symptoms and physicians did not intervene further. Additional tests in the Stanford University hospital revealed a freely moving bladder stone with no mucosal erythema or edema. The physicians removed the 5.2 x 4.5 x 1.5 cm rough calcified mass. When they broke the stone, they found the intact Dalkon Shield IUD which had been completely surrounded by the calcified mass. The physicians were able to discharge the patient 5 days later. This hospital has had a total of 19 cases of uterine perforation by an IUD. The Lippes Loop caused most perforations (6 cases) which took place before 1977. After 1978, however, most cases involved the Dalkon shield (5 cases). Usually the patient had no symptoms when the IUD migrated, but erosion into the bladder often resulted in urinary symptoms, such as repeated urinary tract infections and/or blood in the urine. The duration of symptoms among the 19 cases, which developed many years after IUD insertion, before diagnosis varied from 3 months to 5 years. In the 8 cases where the IUD migrated to the bladder, the erosion took at least 10 years. The case reported here had the longest reported duration period. Once the IUD entered the bladder in 12 cases, calcium at least partially surrounded it.
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PMID:Intravesical migration of intrauterine device. 172 5

Between November 1984 and December 1989, 318 non-cemented Porous Coated Anatomic (PCA; How-medica, Rutherford, New Jersey) total hip replacements were performed by the authors. A follow-up of 1 to 6 years was allowed. The average age was 53.1 years (from 17 to 71 years). The distribution of right-to-left was approximately equal. There were 192 hip replacements for primary and post-traumatic osteo-arthritis, 42 for rheumatoid arthritis, 40 for avascular necrosis, 29 for congenital dislocation or hip dysplasia with secondary osteo-arthritis, 6 for Perthes disease, 5 for previous sepsis, 2 of whom had had a Girdlestone procedure, 2 for revision of a painful cup arthroplasty, and 1 for conversion of a previously fused hip. All patients were evaluated on a one hundred point Harrington Arthritis Research Centre Scale. Points were awarded for pain (0-35), function (0-35), motion (0-10), deformity (0-10) and gait (0-10). Pre-operative total scores averaged 45.5 (9-71) and postoperative scores averaged 83.9 (55-98). The overall results were excellent 20.5% (90-100), good 59.8% (80-90), fair 16.4% (70-80), and poor 3.3%. Postoperative radiographs were evaluated using zonal analysis. There was no deterioration on the radiographs after two years.
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PMID:Porous coated anatomic non-cemented total hip arthroplasty. 173 38

Little is written of the place of aortobifemoral bypass as a limb or below-knee-level amputation stump salvage procedure in patients presenting with critical ischaemia with threat of limb loss. Over a 4-year period 151 patients referred to the Vascular Service of the University of Natal Hospitals with aorto-iliac occlusive disease and a threatened limb were studied. All were submitted to aortobifemoral bypass. Patients were divided into two subgroups: group 1 patients presented with rest pain or focal necrosis and were submitted to aortobifemoral bypass with concomitant digital or transmetatarsal amputation; and group 2 patients were submitted to a guillotine-type below-knee amputation in view of ascending infection or extended necrosis that made below-knee amputation impracticable. The objective was to obtain healing of the stump at the below-knee level. Early results within 1 month of operation were as follows: 5 patients (3.3%) died of myocardial infarction. There was no graft sepsis, and groin wound sepsis occurred in 7 (4.5%). Of the group 1 patients 8 required major amputation (8.2%). Three patients in group 2 required proximal above-knee revision (14.3%). The overall limb or stump salvage rate within 1 month of surgery was 89.4%. It was possible to follow up 105 patients in group 1 and 18 in group 2 for between 2 years and 5 years. In group 1, 2.9% required major proximal amputation and 3.8% a subsequent femoral-to-distal bypass. In group 2 none required subsequent major proximal amputation. Overall in those available for long-term follow-up 97% retained the use of a salvaged limb or stump.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Aortobifemoral bypass for the critically ischaemic limb--is it worth while? 176 91

The authors propose a technique of fixation of the parietal prosthesis by metallic staples in order to reduce the operation time which is often long. The operation was performed according to J Rive's principles, using a Dacron patch (n = 65) or a polyglactin patch (n = 5). A mechanical stapler for aponeurotic suture was used for fixation of the patch. The bent shape of the stapler made it possible to very easily insert the lateral edge of the patch, previously hemmed, to slip it under the rectus abdominis muscle and to clamp it onto the lateral linea alba. We placed the patch under tension very easily with circular clamping. Seventy ruptures were treated by this technique. In 80% of cases, the rupture was frontal and in 20% of cases, it was fronto-lateral. The mean diameter of the parietal defect was 15 cm (E = 10-35 cm). The time for fixation of prosthesis was less than 5 min; the usual duration of the operation was therefore considerably reduced. In every case, we obtained optimal tension of the suture, without any folds, and this very easily. There was no mortality. Two postoperative hematomas, one consecutive to an injury of the epigastric artery required a second operation. We only had one case of superficial parietal sepsis. None of these complications required removal of the parietal prosthesis. The functional results were always satisfactory for the patients who suffered no pain induration over the metallic staples. A radiological follow-up of the position of the prosthesis encircled by the metallic staples was systematically performed after every operation. Only one relapse, due to a technical error, was observed. If we consider that the follow-up of these results is about two years (3 months-5 years), they suggest that the use of a stapler allows strong fixation, without any fold and with a regular tension, of the prosthetic patch used in the treatment of large incisional hernia. If we compare this technique with the usual techniques of fixation, we can say that this technique significantly reduces the duration of the operation which is often long. These technical advantages help to reduce the long operating time and the risk of sepsis, which is always serious, also minimizing recurrences of the rupture.
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PMID:[Method for the correction of ventral hernia using a parietal prosthesis held by a metal stapler. Apropos of seventy cases]. 178 9

This is a retrospective analysis of 82 patients of intussusception in infancy and childhood. Males were more than females in the ratio 2.4 : 1, the ages varied from 2 months to 12 years. Majority (73%) were less than 1 year old. Commonest presentations were pain, vomiting, distension, palpable lump and blood and mucus in stools. The management of these patients varied from barium enema reduction (3 cases), reduction by surgery and manipulation (59 cases) and resection with primary anastomosis (20 cases). We analysed our patients by giving scores based on clinical criteria. We concluded that the patients in our circumstances do not show any correlation of the scoring pattern with morbidity or mortality, chances of reduction by barium enema or manually. Resection, however, did correlate with a high incidence of death (75%). Resections were required slightly more in ileo-ileal intussusceptions than in those having a colonic involvement, morbidity in the form of wound dehiscence, and sepsis was higher in those patients who had undergone resections.
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PMID:Intussusception in infancy and childhood: evaluation of a prognostic scoring pattern. 180 93

Oncology represents a very wide field of applications in interventional radiology. Procedures are diagnostic as well as therapeutic; approaches may be endovascular (either arterial or venous), endocanalar, or transcutaneous; guidance may need X-ray, sonographic, CT scan or endoscopic control. Such a diversity in methods makes clinical and technical training especially long. Main indications of endoarterial approaches are: pain, bleeding, abnormal secretion (endocrine tumors and paraneoplastic syndrome), abnormal function (kidney, spleen), preoperative devascularization of tumors, redistribution of arterial flows before intra arterial chemotherapy, chemoembolizations. Venous pathology is known to be particularly frequent in oncology. Current indications are inferior vena cava filter placement, angioplasty and stenting in case of superior vena cava syndrome, local fibrinolysis, foreign bodies extraction. Drainages, stenosis dilations and stent placements are daily procedures in urinary and biliary tracts in order to treat obstructions, sepsis or fistulas. Transcutaneous approaches under radiological guidance allow biopsies, drainage of deep collections, antalgic nerve infiltrations, gastrostomy. Nowadays, interventional radiology can be considered as a requisite weapon for a correct cancerous patient management, since it is useful from the initial diagnostic biopsy to the palliative care of cancer complications.
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PMID:[Interventional radiology in oncology]. 180 86

Gallbladder disease, with or without the formation of stones, can be treated in a number of ways. Conservative treatment of a low-fat diet may be difficult for the patient to maintain over a period of time, and may be ineffective in the long run. Chemodissolution of gallstones is a costly pharmacologic treatment that may require repeating within a 5-year period. Other forms of treatment include the still experimental shock wave lithotripsy to break up gallstones before chemodissolution therapy, or surgical removal of the gallbladder by traditional open laparotomy or by laparoscopic intervention. Laser laparoscopic cholecystectomy, a procedure suited to the ambulatory surgery setting, can be used for many individuals requiring cholecystectomy. It is less invasive than traditional surgery and results in a shorter hospital stay, less postoperative pain, and more rapid ambulation and recuperation. Most people can return to work in 3 days and can resume full physical activity after 1 week. Potential intraoperative complications include the puncture or rupture of a blood vessel or viscus with resulting hemorrhage or sepsis. Less serious complications in the postoperative time frame can include nausea and vomiting, minimal to moderate abdominal discomfort, and referred shoulder pain secondary to the pneumoperitoneum. A strong social support system is essential for the patient who is discharged to home within 4 to 23 hours after surgery.
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PMID:Laser laparoscopic cholecystectomy in the ambulatory setting. 183 28

Bacteriological and clinical studies on cefodizime (CDZM, THR-221), a new cephem developed by Hoechst AG and Roussel Uclaf, were carried out and the results are summarized below: 1. Against Gram-positive bacteria, Staphylococcus aureus, Streptococcus pyogenes and Streptococcus pneumoniae, antibacterial activities of CDZM were similar to those of cefotaxime (CTX), cefazolin, cefotiam and piperacillin. Against Escherichia coli, Klebsiella pneumoniae and Serratia sp., antibacterial activities of CDZM were similar to that of CTX, and superior to those of other tested antibiotics. Especially against Haemophilus influenzae and Branhamella catarrhalis, it showed an excellent antibacterial activity. 2. Although the clinical efficacy was poor in 1 patient with sepsis caused by Salmonella marcescens and in another with cervical lymphadenitis, in 5 patients with upper respiratory tract infection, 4 patients with bronchitis, 6 patients with bronchopneumonia, 18 patients with pneumonia, 5 patients with urinary tract infection and 1 patient with enteritis, the clinical efficacy was excellent or good and the efficacy rate was 95.1% (39/41) including excellent efficacies in 25 cases. 3. Bacteriologically, all identified causative bacteria were eradicated except for 1 case of Salmonella sp., thus the eradication rate was 97.4% (38/39). Especially S. pneumoniae in 10 cases, H. influenzae in 12 cases and B. catarrhalis in 3 cases were eradicated totally. 4. Adverse reactions were studied in 46 cases, and digestive symptoms were observed in 9 cases (diarrhea 5 cases, loose stools 4 cases). Eruption and vascular pain were observed in 1 case each. As digestive symptoms in 9 cases were mild, the treatment were not suspended. In laboratory test values, elevation of GOT, elevation of GPT, elevation of bilirubin, and eosinophilia were observed in 1 case each. Influences on blood coagulation parameters were studied. No change was observed between the beginning and the end of the treatment. From above results, we have concluded that CDZM is a useful and safe antibiotic in pediatrics, administered at a daily dose of 20 mg/kg divided into 3 or 4 doses and administered intravenously.
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PMID:[Bacteriological and clinical studies of cefodizime in pediatrics]. 188 Sep 19

The barium enema is a safe and accurate diagnostic study of the colon but, in rare cases, complications may result. Many of these can be prevented by proper equipment and careful attention to technique. When a complication does occur, prompt recognition and management is vital in decreasing morbidity and mortality. Perforation of the bowel is the most frequent serious complication, occurring in approximately 0.02% to 0.04% of patients. Rarely the colon may burst due to excessive transmural pressure alone. However, a colon weakened by iatrogenic trauma or disease is more likely to perforate during an enema than is a normal healthy bowel. Injury to the rectal mucosa or anal canal due to the enema tip or retention balloon is probably the most common traumatic cause of barium enema perforation. Inflation of a retention balloon within a stricture, neoplasm, inflamed rectum, or colostomy stoma is particularly hazardous. Recent deep biopsy or polypectomy with electrocautery makes the bowel more vulnerable to rupture. The tensile strength of the bowel wall is impaired in elderly patients, patients receiving long-term steroid therapy, and in disease states including neoplasm, diverticulitis, inflammatory bowel disease, and ischemia. Intraperitoneal perforation leads to a severe, acute peritonitis with intravascular volume depletion. The ensuing shock may be rapidly fatal. Prompt fluid replacement and laparotomy are essential. If the patient survives the initial shock and sepsis, later complications caused by dense intraperitoneal adhesions may develop. Extraperitoneal perforation is usually less catastrophic but may result in pain, sepsis, cellulitis, abscess, rectal stricture, or fistula. Intramural extravasation often forms a persistent submucosal barium granuloma which may ulcerate or be mistaken for a neoplasm. The most dramatic complication of barium enema is venous intravasation of barium. Fortunately, this is quite rare as it may be immediately lethal. Most cases have been attributed to trauma from the enema tip or retention balloon, mucosal inflammation, or misplacement of the tip in the vagina. Bacteremia has been found in as many as 23% of patients following barium enema and, in rare cases, may cause symptomatic septicemia. Other less common complications include barium impaction, water intoxication, allergic reactions, and cardiac arrhythmias. Preparatory laxatives and cleansing enemas have been implicated in some instances of dehydration, rectal trauma, water intoxication, and perforation. Careful review of the indications for examination, previous radiographs, and clinical history will identify many of the patients at greater risk for complications so that appropriate precautions may be observed.(ABSTRACT TRUNCATED AT 400 WORDS)
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PMID:Recognition and prevention of barium enema complications. 188 35


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