Gene/Protein
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Pivot Concepts:
Gene/Protein
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Drug
Enzyme
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Target Concepts:
Gene/Protein
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Enzyme
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Query: UMLS:C0243026 (
sepsis
)
52,417
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Staphylococcus epidermidis is a pathogenic organism with increasing importance in total parenteral nutrition therapy. Strict asepsis during catheter insertion prolongs the interval free from
Staphylococcus epidermidis infection
. Staphylococcus epidermidis colonizes the catheter after migrating from the skin. For protection, we advise a long subcutaneous tunnel for all catheters that are to be indwelling for longer than three weeks. Prompt recatheterization of a patient with Staphylococcus epidermidis
sepsis
can result in hematogenous seeding of the new catheter and persistence of the infection. Catheter related Staphylococcus epidermidis
sepsis
has subsided after catheter withdrawal, and there is no need for antibiotic therapy provided that other prosthetic materials are not placed in the vascular tree. Immunologic status of the patients is not related to the frequency or severity of Staphylococcus epidermidis infections, or both.
...
PMID:Catheter sepsis due to Staphylococcus epidermidis during parenteral nutrition. 677 28
The authors describe a patient with severe head injury and
sepsis
who became acutely quadriplegic 3 days postinjury because of a critical illness polyneuropathy (CIP) and critical illness myopathy (CIM), which resolved rapidly after treatment of the underlying infection. In only 3 days the patient developed septic shock together with flaccid quadriplegia and absent deep tendon reflexes with no clinical or radiological evidence of central nervous system deterioration. Neurophysiological studies showed an acute axonal sensorimotor polyneuropathy, whereas the clinical course strongly suggested a concurrent myopathy. A severe
Staphylococcus epidermidis infection
accompanied by bacteremia was treated and the patient recovered fully within a few days. Although the case described here is unique because of its very early onset and rapid resolution, CIP and CIM are frequent complications of
sepsis
and multiple organ failure. The authors suggest that severely head injured patients with
sepsis
should be evaluated for CIP and CIM when presenting with unexplained muscle weakness or paralysis.
...
PMID:Acute quadriplegia with delayed onset and rapid recovery. Case report. 952 27