Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0243026 (sepsis)
 52,417 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In the past decade, mucormycosis has emerged as an important lethal infection in diabetics and other immunocompromised hosts. Rhinosinusitis, pansinusitis, rhino-orbital and rhinocerebral are the common classical manifestations of mucormycosis. However, primary gastrointestinal (GI) mucormycosis is an uncommon disease associated with a high mortality rate. Stomach is the most common site involved in GI mucormycosis. Reported cases of GI mucormycosis in an immunocompetent host are very few in the literature. Here we present a case of a young male with fungal sepsis secondary to GI mucormycosis in an immunocompetent person.
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PMID:Primary gastrointestinal mucormycosis in an immunocompetent person. 1924 86

Rhino-orbital mucormycosis is a fatal infection. Decompensated diabetes is the most common predisposing factor. Two male adults were admitted because of newly diagnosed diabetes with hyperglycemic hyperosmolar state and CT scan showed extensive pansinusitis and orbital inflammation. Treatment included surgical debridement and antifungal therapy. One patient died from a severe sepsis.
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PMID:Hyperglycemic hyperosmolar state and rhino-orbital mucormycosis. 2110 69

This paper was designed to illustrate the probability of the development of an oncological disease of the nasal cavity and the paranasal sinuses in young subjects presenting with long-standing decompensated chronic sinusitis; also, it demonstrates the possibility of long-term remission after surgical elimination of the inflammatory process. A 28 year-old patient is described having decompensated chronic pansinusitis complicated by sepsis and secondary suppurative dacryocystitis. Multiple surgical interventions on several paranasal sinuses for the treatment of this pathology proved inefficient and were followed by sanation rhinosinusotomy with the simultaneous removal of the malignant tumour. The long-term monitoring of paranasal sinus condition after radical pansinusotomy and ablation of the tumour followed by a course of radiotherapy gave evidence of the malignant process with simultaneous elimination of inflammatory changes in paranasal sinuses.
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PMID:[Decompensated sinusitis complicated by cancer of the nasal cavity and the maxillary sinus]. 2137 48

Mokgacha K, Maruza MP, Sesay SO, Rwegerera GM. Cavernous sinus thrombosis in a 14-year old boy. Turk J Pediatr 2017; 59: 719-723. Cavernous sinus thrombosis (CST) is a rare, life-threatening disorder occurring as a result of sepsis or secondary to aseptic causes in the setting of a thrombophilic disorder that has over the years been linked to high morbidity and mortality rates; this being despite availability of a wide number of new broad-spectrum antibiotics. We present a case of a 14-year old boy who had presented with two weeks` duration of worsening bitemporal headache followed by facial swelling on the background history of chronic non-specific headache of few months duration. He was diagnosed to have cavernous sinus thrombosis secondary to pansinusitis. The course of his illness was complicated by a stroke despite prompt treatment with antibiotics and anticoagulation. The case highlights the importance of high index of suspicion in patients with unexplained headache and need for investigation and early referral to prevent occurrence of cavernous sinus thrombosis.
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PMID:Cavernous sinus thrombosis in a 14-year old boy. 3003 10