Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0242706 (
hyperoxia
)
5,219
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Histamine content and
diamine oxidase
activity in rat brain under hyperbaric oxygenation have been studied. Under 0,3 MPa histamine level decreases in brain of more sensitive rats, but it does not change in brain of more resistant animals in comparison with the control ones. High oxygen pressure (0,7 MPa) causes a significant increase of histamine concentration. Diamine oxidase activity decreases under
hyperoxia
. Under the consequent action of high and low pressure (0,3 MPa during 1 h and 0,7 MPa) convulsions in rats begin later and alterations of histamine content in brain are less than under 0,7 MPa oxygen action only. The role of histamine at compensate reaction and cause of increasing resistance of animals to
hyperoxia
are discussed.
...
PMID:[Links in the histamine metabolism in the brain of rats with sequential exposure to low- and high-pressure oxygen]. 392 92
Content of histamine, activity of
diamine oxidase
in rat brain, liver, lung tissues and blood as well as histaminopexic effect of blood serum were studied after treatment of the animals with oxygen at 0.3 MPa within 60 and 120 min.
Hyperoxia
caused dissimilar alterations in content of blood and tissue histamine: the first group of animals was characterized by a distinct impairment of histamine metabolism in tissues accompanied by a high level of the amine in blood, in the second group these alterations were not found. Role of histamine in compensatory-adaptation mechanisms caused by
hyperoxia
as well as in pathogenesis of oxygen intoxication is discussed.
...
PMID:[Several indicators of histamine metabolism in hyperbaric oxygenation]. 643 11