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Query: UMLS:C0242706 (hyperoxia)
 5,219 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A new apparatus which can measure oxygen tension and temperature in the conjunctiva was tested and compared with measurements of transcutaneous and arterial oxygen tension in eight volunteers in connection with normal oxygen tension, hypoxia and hyperoxia. In hypoxia, the conjunctival oxygen tension was found to be better correlated to and in better agreement with arterial oxygen tension than transcutaneous oxygen tension. The advantages with conjunctival oxygen measurements are continuous measurements in easily accessible and well vascularized tissue with the same arterial supply as the brain. In contrast to transcutaneous measurement, the new method does not require warming of the tissue as the conjunctiva is oxygen permeable.
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PMID:[Conjunctival oxygen tension. Testing oxygen tension measurement of the conjunctiva]. 236 4

A device to measure surface oxygen tension of the palpebral conjunctiva (PcjO2) was developed and tested in 12 mongrel dogs subjected to normoxia, hyperoxia, and hypoxia. Intravascular pressure, hemodynamic, and bulk oxygen transport variables were measured simultaneously with PcjO2 and transcutaneous O2 (PtcO2) and CO2 (PtcCO2). PcjO2 closely paralleled PaO2 as the fractional inspired O2 concentration was changed from 0.21 up to 1.0 and down to 0.05; the correlation coefficient, r, was 0.95 for 305 data sets. During hyperoxia there were no significant hemodynamic or bulk O2 transport changes, but during hypoxia, the cardiac output and O2 extraction increased while PaO2, PtcO2 and PcjO2 fell; O2 delivery and O2 consumption were maintained until just before death.
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PMID:Oxygen transport and utilization in hyperoxia and hypoxia: relation of conjunctival and transcutaneous oxygen tensions to hemodynamic and oxygen transport variables. 649 78