Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0242429 (sore throat)
 2,760 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Fourteen patients with common variable immunodeficiency (CVID) were studied. The common clinical manifestations were recurrent sore throat, sinusitis, respiratory infections, diarrhea, and malnutrition. All had low IgG, with normal cell-mediated immunity. Treatment with immunoglobulin and/or plasma was effective in most of them. There were no severe adverse events with the therapy.
Asian Pac J Allergy Immunol 1994 Dec
PMID:Common variable immunodeficiency (CVID) in northern India. 761 12

The incidence of acute rheumatic fever (ARF) and its sequela rheumatic heart disease (RHO) is disproportionately high among the children of Western Samoa. Basic symptoms of ARF include fever, joint pain, and a sore throat. The condition of strep throat, if left untreated, may initiate an immune response which can damage the heart and become RHD. Primary prevention currently consists of educating locally trained nurses to detect strep throat and dispense antibiotics as necessary. The concept of targeting proximal caregivers with prevention information has not been explored. Health behavior theories offer methodology for the development, implementation, and evaluation of health promotion programs. This study incorporates the interpersonal level of the ecological model (EM) in conjunction with the four elements of the social change model (SCM) which are critical thinking, fundamental skills, cultural sensitivity, and action. The purpose of this study was to test the hypothesis that an educational prevention program can be effective in disseminating pertinent information regarding ARF prevention. This study followed a matched-pairs, same subject design, using a pre-/post-survey as the observational tool in which to measure the effectiveness of the presentation. The question that targeted trust of health care workers showed a statistically significant increase (p = < .0001) from approximately 50% in the pre-survey to 73% in the post-survey. The question regarding antibiotic treatment was slightly significant for the pre-survey (p = 0.0428), but showed increased statistical significance for the post-survey (p -< 0.0001). Responses targeting the contagious factor changed in significance between the pre- and post-survey from p = .009 to p = < .001. The response change for the question targeting the possibility of a child contracting a sore throat as school changed from p = .0123 to p = < < .0001. These findings support the use of a basic and inexpensive educational prevention program.
Pac Health Dialog 2011 Mar
PMID:Rheumatic fever in Samoa: education as prevention. 2300 75

Medicinal plants are part and parcel of human society to combat diseases from the dawn of civilization. Terminalia chebula Retz. (Fam. Combretaceae), is called the 'King of Medicine' in Tibet and is always listed at the top of the list of 'Ayurvedic Materia Medica' because of its extraordinary power of healing. The whole plant possesses high medicinal value and traditionally used for the treatment of various ailments for human beings. Some of the folklore people used this plant in the treatment of asthma, sore throat, vomiting, hiccough, diarrhea, dysentery, bleeding piles, ulcers, gout, heart and bladder diseases. The plant has been demonstrated to possess multiple pharmacological and medicinal activities, such as antioxidant, antimicrobial, antidiabetic, hepatoprotective, anti-inflammatory, antimutagenic, antiproliferative, radioprotective, cardioprotective, antiarthritic, anticaries, gastrointestinal motility and wound healing activity. But no systematic updated information on the therapeutic effectiveness of Terminalia chebula, a popular herbal remedy in India and South-East Asia has so far been reported. This review highlights an updated information particularly on the phytochemistry and various pharmacological and medicinal properties of Terminalia chebula Retz. and some of its isolated compounds, along with their safety evaluation. This may provide incentive for proper evaluation of the plant as medicinal agent against the human diseases and also to bridge the lacunae in the existing literature and future scope which may offer immense opportunity for researchers engaged in validation of the traditional claims and development of safe and effective botanical medicine.
Asian Pac J Trop Biomed 2013 Mar
PMID:The development of Terminalia chebula Retz. (Combretaceae) in clinical research. 2362 Aug 47

The pandemic of coronavirus disease has created a global emergency after its origin in China, in December 2019. We investigated SARS-CoV-2 infection in the local population of a prime city of Western Rajasthan in India and found that the co-morbidities like diabetes (54.3%), cardiovascular diseases (28.8%), chronic respiratory conditions (18.4%) are the predominant risk factors for acquiring the infection. The young adult male population from urban area were maximum affected by the disease. Most common presenting complains were dry cough (65.7%), fever (62.3%) followed by sore throat (24.1%). A declining positive case percentage was found over the study period, though the number of samples received for SARS-CoV-2 testing increased with time, implying the effectiveness of government policies at community level to spread the outbreak.
Asia Pac J Public Health 2020 Dec 08
PMID:Demographic Profile of COVID-19 Cases: An Early Analysis of the Local Outbreak in a "Hotspot District" of Western Rajasthan in India. 3328 99