Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0242429 (sore throat)
 2,760 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Aerobic dance has recently become popular in all age groups, but the injuries among full-time and part-time aerobic dance instructors have rarely been pointed out in Japan. In this study the subjective symptoms of 63 female instructors in Gifu area were evaluated through health questionnaire. As a control group, 94 female students of the same age group were also included to compare the prevalence of subjective symptoms. Multiple logistic regression analysis was applied to observe the relation between instructors' symptoms and working conditions. The following results were obtained: 1) Complaints of leg and foot pain and laryngeal discomfort were significantly greater in instructors than in students even after adjusting for age and participation in other sports. 2) A significant positive relation was found in instructors between the frequency of dance lessons (times/wk) and various symptoms (calf pain, foot pain, sore throat, and hoarse voice) after adjusting for age and participation in other sports. These results suggest that leg and foot pain and laryngeal discomfort are characteristic symptoms of aerobic dance instructors. Consideration should be made to adjust the frequency of dance lessons in order to reduce these symptoms.
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PMID:[Health condition of female aerobic dance instructors. Subjective symptoms and related factors]. 151 88

The possibility that air pollution exposure can extend the duration of respiratory symptoms was examined in a diary study of student nurses. This diary study has already shown associations between air pollution and incidence rates of respiratory symptoms. After individual risk factors and temperature were controlled for, photochemical oxidants were significantly (p less than .0001) associated with the duration of episodes of coughing, phlegm, and sore throat. Some heterogeneity of response to oxidants was seen; there was little effect on asthmatics, but the impact increased as family income increased. Plots of the mean duration of symptoms, by quintiles of oxidants, for which the other covariates were controlled, showed strong signs of a dose-response relationship for coughing and phlegm and moderate signs of a monotonic dose-response relationship for sore throat. The relationships continued for concentrations below the current ambient standard for ozone. Chest tightness or discomfort was significantly associated with sulfur dioxide (p = .016), but the effect seemed mainly restricted to asthmatics. However, evidence for a dose-dependent increase was weak.
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PMID:Air pollution and the duration of acute respiratory symptoms. 156 34

Exposure to environmental tobacco smoke (ETS) is a potential occupational carcinogen according to guidelines of the Occupational Safety and Health Administration (OSHA) carcinogen policy (1). Exposure to ETS in the workplace may represent a substantial contribution to lifetime ETS exposure (2). For many persons, ETS irritates the conjunctiva of the eyes (accompanied by reddening, itching, and increased lacrimation) and the mucous membranes of the nose, throat, and lower respiratory tract (accompanied by itching, coughing, and sore throat) (3). As part of the 1988 National Health Interview Survey-Occupational Health Supplement (NHIS-OHS), CDC measured the degree of discomfort caused by ETS in the workplace. The NHIS-OHS collected information on cigarette smoking, workplace smoking restrictions, and perceived discomfort caused by ETS at the workplace. This report summarizes survey findings and describes efforts to reduce ETS at the workplace.
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PMID:Discomfort from environmental tobacco smoke among employees at worksites with minimal smoking restrictions--United States, 1988. 158 92

Between 1 January 1980, and 30 September 1989, 93 cases of exposure to herbicides containing glyphosphate and surfactant ('Roundup') were treated at Changhua Christian Hospital. The average amount of the 41% solution of glyphosate herbicide ingested by non-survivors was 184 +/- 70 ml (range 85-200 ml), but much larger amounts (500 ml) were reported to have been ingested by some patients and only resulted in mild to moderate symptomatology. Accidental exposure was asymptomatic after dermal contact with spray (six cases), while mild oral discomfort occurred after accidental ingestion (13 cases). Intentional ingestion (80 cases) resulted in erosion of the gastrointestinal tract (66%), seen as sore throat (43%), dysphagia (31%), and gastrointestinal haemorrhage (8%). Other organs were affected less often (non-specific leucocytosis 65%, lung 23%, liver 19%, cardiovascular 18%, kidney 14%, and CNS 12%). There were seven deaths, all of which occurred within hours of ingestion, two before the patient arrived at the hospital. Deaths following ingestion of 'Roundup' alone were due to a syndrome that involved hypotension, unresponsive to intravenous fluids or vasopressor drugs, and sometimes pulmonary oedema, in the presence of normal central venous pressure.
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PMID:Acute poisoning with a glyphosate-surfactant herbicide ('Roundup'): a review of 93 cases. 167 18

A 17-year-old boy had a 2-day prodrome of fever and mild sore throat followed by 2 episodes of severe anginal chest discomfort and substantial transient ST-segment elevations in the anterior leads of the electrocardiogram. A subsequent evaluation showed the 2 episodes were most likely coronary vasospasm complicating acute viral myocarditis.
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PMID:Coronary artery vasospasm complicating acute myocarditis. A rare association. 317 73

A double-blind, randomized clinical study was undertaken to determine the analgesic and antiinflammatory effectiveness of benzydamine in patients with radiation-induced mucositis of the oropharynx. Of the 67 patients in the study, 37 patients were on benzydamine and 30 patients on a placebo. The results of the study showed that benzydamine possessed a significant analgesic activity as evidenced by relief of mouth and throat pain induced by radiation therapy. It is also noted that the patients on benzydamine exhibited a cumulative relief of oral pharyngeal pain and discomfort over the time of treatment, as compared to those on the placebo. These effects of benzydamine in the present study might be a result of the antiinflammatory property of the drug. The cumulative and prolonged effectiveness of benzydamine makes it of distinct value compared with the commonly available local anaesthetics such as lidocaine. Benzydamine appears to provide a useful addition to the therapeutic armamentarium for alleviating the symptoms of oral pharyngeal mucositis.
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PMID:A clinical study of benzydamine for the treatment of radiotherapy-induced mucositis of the oropharynx. 389 70

Spontaneous pneumomediastinum is an uncommon disease that often presents with subtle clinical and radiographic findings. During a two-week period, three patients presented with complaints of throat and neck pain. The first complained of difficulty swallowing and throat and chest discomfort; accurate diagnosis was delayed because of the unusual presenting symptoms. The second had severe throat pain. The third presented with unstable vital signs, throat and neck pain, and air in the pericardium and mediastinum. Review of the first case facilitated the correct diagnosis of spontaneous pneumomediastinum in the subsequent cases. All three patients were discharged free of symptoms.
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PMID:An unusual presentation of spontaneous pneumomediastinum. 403 67

Severe respiratory tract irritation occurred in at least 74 of 100 boilermakers who were exposed to high levels of vanadium pentoxide fume during oil-to-coal conversion of a utility company power plant in a rural area of western Massachusetts. Many were welders working in confined areas with inadequate ventilation. Most frequent symptoms were productive cough, sore throat, dyspnea on exertion, and chest pain or discomfort. The illness was severe enough to cause 70 workers to consult physicians and most of them to lose time from work (median, five days). Wheezing (in 39%) was the most frequent finding on physical examination. Mild hypoxemia was noted in several workers; most (72%) had normal chest x-ray films. Expiratory flow rate over the middle 50% of the forced vital capacity was the pulmonary function test most remarkably affected (median, 57% of predicted for 24 workers tested). The Occupational Safety and Health Administration documented levels of vanadium pentoxide fume at or above the permissible exposure limit in all eight air samples taken from inside the boiler; it cited the company for inadequate mechanical ventilation and an inadequate respiratory protection program for workers. The report of this outbreak may help prevent future problems by drawing attention of physicians, workers, and managers to the potential pulmonary hazards in power plant conversion.
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PMID:Boilermakers' bronchitis. Respiratory tract irritation associated with vanadium pentoxide exposure during oil-to-coal conversion of a power plant. 633 88

The aim of this study was to observe the effects of the position of the tracheal tube on cardiac performance or sedation requirements after cardiac surgery. There were no significant differences in heart rate, systolic blood pressure, or rate-pressure product during the first 16 hours postoperatively when 41 orally intubated patients were compared with 32 patients who were reintubated nasally. The two groups received similar amounts of sedative drugs postoperatively. During attempted nasal intubation, bleeding developed in four patients, and in three of these and four others the tube could not be passed. Failed nasal intubation gave rise to nasal discomfort in three of seven patients. Orally intubated patients complained more often of sore throat after extubation, whereas those who had been nasally intubated complained of discomfort in the nose and throat. We conclude that nasal re-intubation carries no advantage over oral intubation for ventilation after cardiac surgery.
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PMID:Oral or nasal intubation after cardiac surgery? A comparison of effects on heart rate, blood pressure and sedation requirements. 671 88

One hundred and seventy-one children up to 15 years of age and with acute otalgia were examined to find out whether otalgia or any other symptoms were so closely related to acute otitis media (AOM) as to make otoscopic examination unnecessary. AOM was diagnosed in 46%, simplex otitis in 15%, serous otitis media (SOM) in 17%, and normal eardrums in 22%. Children with AOM had fever and spontaneous perforation of the eardrums in 78% and 30% of the cases, respectively. Of the children who had not AOM (54%), the otalgia could in most cases be classified as referred pain due to, for instance, discomfort when swallowing, nasal obstruction or throat pain. Other reasons were general irritability due to fever, teething or moderate hearing loss. The difficulties in diagnosing AOM simply on the basis of symptoms were demonstrated in the investigation. Symptoms such as otalgia, otorrhea, fever or upper respiratory tract infection (URI), possibly except for the combination of otorrhea and fever, can occur without AOM. A correct otoscopic examination and evaluation of the eardrums is necessary in children with otalgia, other symptoms of URI or in doubtful cases of acute illness. Physicians without possibilities to evaluate the eardrums properly should thus refer the patient to an otologist without delay.
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PMID:Acute otalgia in children - findings and diagnosis. 689 Nov 67


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