Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0242429 (
sore throat
)
2,760
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Carcinoma showing thymus-like differentiation
(
CASTLE
) is a rare carcinoma of the thyroid or adjacent soft tissue of the neck with a histologic resemblance to thymic epithelial tumors. Although the fine-needle aspiration (FNA) plays a central role in the initial evaluation of thyroid nodules, few reports about the cytologic findings of
CASTLE
have been found according to a review of literatures. We report cytologic findings of a case of
CASTLE
. A 34-year-old woman presented with a 2-month history of
sore throat
. The FNA showed that the smear was composed of three dimensional clusters and sheets. The tumor cells were round to ovoid with high nuclear : cytoplasmic ratios. The nuclei were vesicular with small nucleoli. There were some tumor cells showing keratinization. Some lymphocytes were found on the background and within clusters. The presence of poorly-differentiated tumor cells with a focal keratinization and a lymphocytic background on the FNA is suggestive of
CASTLE
.
...
PMID:Cytologic Findings of Thyroid Carcinoma Showing Thymus-like Differentiation: A Case Report. 2311 20