Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0242429 (sore throat)
 2,760 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This study was carried out in 165 patients submitted to the surgery of tonsils or adenoid from 1977 to 1989 at the Botucatu Medical School Hospital. The clinical signs and histopathological findings were reviewed. All patients exhibited similar complaints with recurrent tonsillitis, sore throat, dysphasia, high temperature, and enlarged tonsils. After surgery, the tonsils was submitted to histopathological study and showed "grains" in the crypts in 6 cases. Four cases (2.4%) of Actinomyces and two (1.2%) of Botryomyces were identified. Any clinical peculiarity was identified with the presence of these "grains."
Auris Nasus Larynx 1991
PMID:Actinomycosis and botryomycosis of the tonsil. 182 Jul 46

Fibrous histiocytomas usually occur in the dermis and superficial subcutis. Involvement of the tongue is extremely rare. A 51-year-old female, referred to us for a sore throat, was noted on intraoral examination to have a polypoid mass with a smooth mucosal surface on the base of the tongue. This lesion was excised because of its probable continuing growth. This tumor, which showed staining for alpha 1-antichymotrypsin, was pathohistologically diagnosed as fibrous histiocytoma. This was the second documented case of fibrous histiocytoma of the tongue.
Auris Nasus Larynx 1990
PMID:Fibrous histiocytoma of the tongue base. 216 49

A case of bilateral peritonsillar abscesses is reported. The patient was a 31-year-old male presenting with a severe sore throat, dysphagia, trismus and bilateral swelling of the soft palate causing no displacement of the uvula. Incision and drainage (I and D) and an interval tonsillectomy cured this condition. On review of the literature, it was noted that bilateral peritonsillar abscesses are not uncommon. Peritonsillar abscesses possibly occur bilaterally, but as the developmental stages of the abscesses are not simultaneous, immediate tonsillectomy or intensive antibiotic treatment following I and D controls the formation of the opposite side abscess in most cases.
Auris Nasus Larynx 1981
PMID:Bilateral peritonsillar abscesses. 694 87

A 73-year-old man presented to our hospital with a sore throat (left-sided) and hiccups. The patient had mucosal swelling and erosions affecting the left posterior pillar, base of tongue, epiglottis, arytenoid, and aryepiglottic fold. As the laryngeal mucosal edema became worse, herpetic vesicles and erosions developed on the left cavum conchae, external auditory canal, and palate. The patient was treated with acyclovir and a steroid. His hiccups were treated with metoclopramide, but it had little effect, and hiccups only subsided gradually after the disappearance of erosions. His hiccups relapsed transiently with vomiting, and then resolved completely. Elevation of the CF titer after 2 weeks confirmed the diagnosis of herpes zoster. This condition should be considered in patients with unilateral sore throat and intractable hiccups, and treatment with acyclovir should be provided.
Auris Nasus Larynx 2009 Oct
PMID:Herpes zoster laryngitis with intractable hiccups. 1926 32

With the increase in the number of patients undergoing warfarin therapy, reports of complications due to such therapy have become frequent. Although upper airway obstruction secondary to bleeding resulting from warfarin therapy is rare, it is a life-threatening complication because of the risk of airway obstruction. Only one previous case of hematoma of the epiglottis and arytenoids has been reported. We here in report a case of an 83-year-old woman on warfarin therapy who presented with a sore throat. On flexible nasoendoscopy, edema of the epiglottis and bilateral arytenoids with a red and purple hue were observed. The left true vocal cord was erythematous, but the airway was adequately maintained. The PT-INR of the patient was 10. She was managed conservatively and had a good course.
Auris Nasus Larynx 2010 Feb
PMID:Upper airway obstruction by epiglottis and arytenoids hematoma in a patient treated with warfarin sodium. 1941 Mar 98

We report four cases of acute epiglottitis with a peritonsillar abscess originating from the inferior pole of the palatine tonsil. All cases were male, and presented with acute onset of sore throat and dysphagia. Flexible laryngoscopy revealed swollen epiglottis and swelling at the base of tongue along the edge of the epiglottis in all cases. Computed tomography (CT) revealed the position and extent of a peritonsillar abscess. Surgical drainage was not performed. Abscesses decreased in size following intravenous antibiotics and corticosteroids. We surmise that inflammatory exudates extending widely in the pre-epiglottic space cause epiglottic swelling from oropharyngeal infection, the latter of which is thought to produce a peritonsillar abscess. We recommend CT examination for patients with a stable airway and swollen epiglottis, even if the swelling is mild. This will allow for exclusion of deep neck abscess and determination of the most effective treatment including intravenous antibiotics against anaerobe, incision and drainage of an abscess.
Auris Nasus Larynx 2011 Apr
PMID:Four cases of acute epiglottitis with a peritonsillar abscess. 2080 Mar 96

Pharyngeal tuberculosis is a rare disease, and its commonly reported symptoms include sore throat, dysphagia, and throat discomfort. The dysphagia in pharyngeal tuberculosis cases is not due to pharyngolaryngeal paralysis but due to odynophagia. Herein, we describe the first case of dysphagia caused by pharyngolaryngeal paralysis secondary to pharyngeal tuberculosis. An irregular mass at the right nasopharynx was detected in a 57-year-old female patient, along with dysphagia and hoarseness. She had poor right soft palate elevation, inadequate right velopharyngeal closure, poor constrictor pharyngus muscle contraction, and an immobilized right vocal cord, which collectively indicate right pharyngolaryngeal paralysis. Pathological examination and culture testing revealed pharyngeal tuberculosis. She was diagnosed with pharyngolaryngeal paralysis secondary to pharyngeal tuberculosis. The pharyngolaryngeal paralysis resolved after beginning anti-tuberculous treatment. Right pharyngolaryngeal paralysis was attributed to glossopharyngeal and vagus nerve impairment in the parapharyngeal space. Prior reports indicate that peripheral nerve paralysis, including recurrent laryngeal nerve paralysis caused by tuberculous lymphadenitis, often recovers after anti-tuberculous treatment. Pharyngeal tuberculosis rarely causes dysphagia and hoarseness attributable to pharyngolaryngeal paralysis. The neuropathy may recover after anti-tuberculous treatment. Pharyngeal tuberculosis is a new potential differential diagnosis in pharyngolaryngeal paralysis.
Auris Nasus Larynx 2015 Feb
PMID:Pharyngolaryngeal paralysis in a patient with pharyngeal tuberculosis. 2528 69

Invasive aspergillosis is a life-threatening infection in immunocompromised hosts and occurs most frequently in the lungs. Invasive laryngeal aspergillosis is extremely rare. Due to the potential progression of invasive aspergillosis, antifungal therapy must be started immediately in cases involving clinical suspicion of the disease. A 65-year-old male with agranulocytosis complained of sore throat and dysphagia. His epiglottis was covered with caseating granulomatous lesions and the tissue was easily disrupted. A histopathological examination showed an aggressive invasion of Aspergillus species and cartilage destruction. Therefore, we made a diagnosis of primary invasive epiglottic aspergillosis. The invasive aspergillosis resolved with antifungal therapy and an increase in neutrophils. It is therefore necessary to include invasive laryngeal aspergillosis in the differential diagnosis when encountering immunocompromised patients presenting with laryngeal granulomatous lesions and laryngitis-like symptoms.
Auris Nasus Larynx 2015 Dec
PMID:Invasive epiglottic aspergillosis: A case report and literature review. 2602 77

A 46-year-old man presented with sore throat. Laryngoscopic findings revealed a smooth yellow mass occupying the anterior portion of the false vocal fold on the left side. The authors performed biopsy under general anesthesia. The histopathological diagnosis was ectopic salivary gland. Because salivary glands are usually not found under the false vocal fold mucosa, ectopic salivary gland of the larynx was diagnosed. It is necessary to consider the possibility of ectopic salivary gland for mass lesions if swelling of the provisional vocal cord is found.
Auris Nasus Larynx 2018 Jun
PMID:A case of ectopic salivary gland of the larynx. 2884 9

A case of laryngeal actinomycosis occurred after bone marrow transplantation was reported. The patient was a 14-year-old girl who had a history of bone marrow transplantation for the treatment of acute lymphocytic leukemia 4month before the onset of the disease. She was referred to our hospital complaining persistent sore throat since 2weeks ago. Fiberscopic observation proved the presence of white tumor-like mass on her right arytenoid of the larynx. As CT image demonstrated that the mass was localized at the arytenoid region with central low-density area surrounded by granulation tissue, we underwent biopsy under local anesthesia. Excision of the mass proved it to be a soft granulation including sulfur granules. Oral administration of amoxicillin 750mg per day was initiated as a postoperative medication. On day 17, histological study confirmed that the tumor-like mass was Actinomyces granuloma, and therefore amoxicillin administration continued. The medication was effective to subside the disease and the arytenoid lesion healed on day 31. Amoxicillin was further administered until day 70 to prevent recurrence. At 6month after the biopsy, she was free from the disease.
Auris Nasus Larynx 2019 Dec
PMID:Post-transplantation laryngeal actinomycosis. 3057 93


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