Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0242429 (sore throat)
 2,760 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case of Epstein-Barr virus infection with neurological complications is described. An 18-year-old man developed cranial neuropathy and peripheral sensorimotor polyneuropathy three weeks after a sore throat. Though severely affected initially, he made a good recovery and no specific therapeutic intervention appears to have influenced his clinical course.
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PMID:Cranial and peripheral neuropathy due to Epstein-Barr virus infection. 933 28

In addition to facial and vestibular nerve paralysis, patients with Ramsay Hunt syndrome may also show glossopharyngeal, vagal, and hypoglossal nerve paralysis. We report a case of Ramsay Hunt syndrome with cranial polyneuropathy including cranial nerves VII, VIII, IX, and X. A 58-year-old rheumatic woman suffering from vertigo, right earache, and sore throat suffered right-side facial palsy, hoarseness, and swallowing difficulty on day 5. Admitted on day 6, she was treated with antiviral medication and steroids. Although vertigo, facial palsy, and hearing loss gradually improved, hoarseness required over three months to recover. Of the 33 patients with Ramsay Hunt syndrome we have seen, 9 (27%) had cranial polyneuropathy, including cranial nerves IX and X in 4 years. Of these, 9% involved total paralysis of nerves IX and X. Physical symptoms of those with polyneuropathy, especially vagal nerve palsy, tended to worsen, making it important to observe other cranial nerve signs, such as for IX and X carefully, in addition to VII and VIII.
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PMID:[Ramsay Hunt syndrome with cranial polyneuropathy involving cranial nerves VII, VIII, IX, and X]. 1986 Feb 68

We present a case of a Caucasian woman aged 67 years referred with a 4-day history of sore throat, dysphagia, fever and nasal blockage. Examination revealed a swollen neck and pharyngeal pseudomembrane. A throat swab was positive on culture for Corynebacterium ulcerans, with toxin expression confirmed on PCR and Elek testing. A diagnosis of classical respiratory diphtheria was made, with subsequent confirmation of the patient's domesticated dog as the source of infection. The dog had recently been attacked by a wild badger and was being treated for an ear infection. The patient made a good recovery with intravenous antimicrobial and supportive therapy; however, she subsequently developed a diphtheritic polyneuropathy in the form of a severe bulbar palsy with frank aspiration necessitating percutaneous endoscopic gastrostomy feeding. A mild sensorimotor peripheral neuropathy was also diagnosed. The patient eventually made an almost complete recovery.
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PMID:Multidisciplinary approach to the management of a case of classical respiratory diphtheria requiring percutaneous endoscopic gastrostomy feeding. 2826 6