Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0242429 (sore throat)
 2,760 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Being a unique Chinese diagnostic measure, this method focussing its observation on the ventral vessels of the tongue, is first recorded in Neijing, saying that it is indicated when the vessels are varicose by puncturing for bloodletting in malaria, mad, and sadness. Ge Hong and Cao Yuanfan applied it for juandice, also for prognosis. Yimenfang predicts by this method the diagnosis for prognosis of the mother and foetus in difficult delivery, while Chen Zhiming popularized it in his Chan Nan sheng Si Jue. Inherited from the theory of Collateral Vessel Diagnosis, this approach pays attention to the observation of the forms and colors of collateral vessel, claiming that dark green color and congestion have bad diagnosis. Though not well developed, it was applied as extra-acupoints for swelling tongue, sore throat and jaundice. While Zhou Xuehai elaborated Liu Shouzhen's idea and put forward a theory of minute-vessel-stasis which is wonderfully conincided with modern microciroulation theory. In 1964, Zhang Zanchen again advocated its diagnostic value in tumor, hepatopathy and cor pulmonale.
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PMID:[Textual research on diagnosis by lingual vessels]. 1161 75

Human respiratory syncytial virus (RSV) is an enveloped, single-stranded, negative-sense RNA virus and member of the Paramyxoviridae family of the genus Pneumovirus that was first reported as a major pathogen in pediatric populations. However, since its discovery, RSV has not infrequently been detected in adults. Reinfection occurs throughout life, with more severe disease occurring in older adults, immunocompromised patients, and those with underlying cardiopulmonary disease. Initially described as the cause of nursing home outbreaks of respiratory disease, there is a now significant body of literature describing the clinical importance of RSV in older adults in a multitude of settings including long-term care, adult daycares, and in community-dwelling adults. Moreover, recent reports from China and other countries emphasize that RSV is a global pathogen that will become increasingly important in developed nations with aging populations. Annual attack rates in the USA range from 2 to 10% in community-dwelling older adults and 5-10% in older adults living in congregate settings. Population-based calculations of the proportion of acute respiratory illnesses attributable to RSV estimate that 11,000 elderly persons die annually in the USA of illnesses related to RSV infection. Clinical manifestations of RSV infections are similar to that of other viral respiratory pathogens and include cough, nasal congestion, rhinorrhea, sore throat, and dyspnea. Lower respiratory tract disease is common and may result in respiratory failure (8-13%) or death (2-5%). Recent advances in molecular diagnostics have made it possible to rapidly identify RSV infection using nucleic acid amplification tests, although clinicians will need to suspect the diagnosis when viral activity is high. At the present time, treatment is supportive. Effective antiviral agents for the treatment and vaccines for prevention of RSV remain a significant unmet medical need in the older adult population.
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PMID:Respiratory syncytial virus infection in older adults: an under-recognized problem. 2585 Dec 17