Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0242379 (lung cancer)
71,905 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 4516
Mol 3235
epidermal growth factor receptor 2431
p53 2393
tyrosine kinase 2323
EGFR 1910
caspase-3 841
AKT 781
KRAS 733
Bcl-2 704
TNM 691
ALK 638
PI3K 594
vascular endothelial growth factor 583
nodal 580
E-cadherin 561
cytokine 554
ERK 539
mTOR 532
anaplastic lymphoma kinase 522
p21 472
PD-L1 461
FDG 433
MAPK 430
catenin 425
cage 407
MET 401
PD-1 359
NMR 358
cyclin D1 348
She 347
carcinoembryonic antigen 345
CD8 343
K-ras 332
histone 330
PARP 328
ERK1 326
HER2 325
BRAF 324
ATP 321
ROS 315
MRI 313
STAT3 301
VEGF 300
matrix metalloproteinase 296
vimentin 295
Epidermal growth factor receptor 292
p38 292
IL-6 289
tumor necrosis factor 280
CD4 275
MEK 268
epidermal growth factor 266
collagen 255
CEA 253
receptor tyrosine kinase 251
caspase-9 247
TNF 243
COPD 241
MMP-9 237
Pol 231
annexin V 230
interferon 228
p16 226
proteasome 224
JNK 219
ROS1 212
glycoprotein 211
MMP-2 209
PTEN 208
CYP1A1 206
ubiquitin 206
UTR 206
survivin 205
ras 203
IFN 202
DDP 201
GSTM1 195
kit 194
Ki-67 194
more...
Disease
lung cancer 71905
cancer 31891
tumor 19028
lung carcinoma 12580
non-small cell lung cancer 7825
adenocarcinoma 6931
breast cancer 3608
metastases 3570
carcinoma 3278
squamous cell carcinoma 2973
carcinogenesis 2705
tumor growth 2264
tumorigenesis 2188
small cell lung cancer 2075
melanoma 1575
tumor progression 1524
chronic obstructive pulmonary disease 1315
prostate cancer 1252
gastric cancer 1204
colorectal cancer 1161
pneumonia 1094
mesothelioma 984
colon cancer 979
leukemia 944
primary tumor 745
tuberculosis 722
lymphoma 702
ovarian cancer 693
asthma 691
hepatocellular carcinoma 670
brain metastases 659
adenocarcinoma of the lung 576
liver cancer 563
pancreatic cancer 557
neutropenia 546
lung disease 541
bladder cancer 532
cervical cancer 523
liver cancer 499
emphysema 473
bronchogenic carcinoma 458
esophageal cancer 403
MCF 389
Hodgkin's disease 389
diabetes 386
renal cell carcinoma 376
thrombocytopenia 375
Thoracic 373
esophageal cancer 369
anemia 345
multiple myeloma 341
head and neck cancer 326
bone metastases 310
sarcoma 308
cardiovascular disease 297
pulmonary fibrosis 296
renal cancer 291
respiratory disease 278
asbestosis 273
malignant mesothelioma 268
idiopathic pulmonary fibrosis 267
hypertension 266
skin cancer 261
lymphadenopathy 259
myelosuppression 254
glioblastoma 254
myocardial ischemia 250
stroke 248
pulmonary tuberculosis 248
DDP 244
sarcoidosis 243
COPD 241
leukopenia 240
interstitial pneumonia 233
interstitial lung disease 232
pneumothorax 231
depression 231
HIV 231
glioma 223
heart disease 223
more...
Symptom
pain 669
dyspnea 578
cough 497
diarrhea 321
fatigue 320
hemoptysis 314
vomiting 286
nausea 278
anesthesia 232
chest pain 212
nausea and vomiting 193
anorexia 161
weakness 142
cachexia 111
headache 110
respiratory distress 100
shortness of breath 96
collapse 91
abdominal pain 82
discomfort 78
constipation 66
seizures 62
back pain 60
discomfort 60
starvation 55
bone pain 53
asthenia 49
clubbing 46
exhaustion 45
chronic cough 41
analgesia 40
stigma 39
angina 37
hoarseness 35
overweight 35
cancer pain 34
myalgia 33
arthralgia 33
exertional dyspnea 32
productive cough 32
numbness 31
ataxia 31
erythema 31
Ill 30
insomnia 26
wheezing 25
dizziness 25
persistent cough 23
paresthesia 23
vertigo 22
sleepiness 21
shoulder pain 21
epigastric pain 20
dysarthria 18
syncope 18
agitation 17
cerebellar ataxia 16
chills 16
hemiplegia 15
myoclonus 15
low back pain 15
decreased appetite 14
acidity 14
facial pain 14
paresis 13
blurred vision 12
memory loss 12
polyuria 11
stridor 11
dry skin 11
hyperoxia 10
cyanosis 10
tremor 10
flank pain 10
spasm 9
dysesthesia 9
hopelessness 9
flushing 9
splenomegaly 8
ophthalmoplegia 8
more...
Drug
Cardiovasc 875
Gefitinib 323
ROS 313
Erlotinib 227
Docetaxel 167
lysine 165
vitamin E 152
IL-2 147
Taxol 144
CSF 141
Monit 138
CPT-11 127
ascorbate 123
Pemetrexed 122
ROC 113
MRC 108
Bevacizumab 107
GEO 106
Vinorelbine 99
Adriamycin 94
IFN-gamma 90
Irinotecan 90
Dermatol 78
EPA 68
Tarceva 66
Mutagen 65
Vitamin A 65
G-CSF 63
Etoposide 59
TTC 56
CTX 55
Cetuximab 49
Taxotere 47
Gemzar 47
Navelbine 46
Glutathione 44
Leaf 41
Zoledronic acid 35
Tocopherol 34
ABC 33
Zoledronic acid 33
MAP 32
ETS 32
Herceptin 31
uPA 30
CTX 30
CTX 30
Gel 29
NADH 28
caffeine 28
ADM 27
Asthma 27
ADR 27
Arsenic trioxide 26
Paraffin 26
Photofrin 26
CAM 26
Silica 26
VCR 25
Alimta 24
Paraplatin 23
Asn 23
Vitamin E 22
Bortezomib 22
Imatinib 21
Retinoic acid 20
PTH 20
VCR 20
CTC 19
Parkin 18
CTC 18
Spectrum 18
Parkin 18
Sorafenib 17
ENT 16
NovoSeven 16
CCL 15
G418 15
TiO2 15
Heme 15
more...
Enzyme
ERK 3798
mitogen-activated protein kinase 1217
caspase-3 653
luciferase 618
focal adhesion kinase 508
protein kinase 428
MEK 349
PARP 347
proteasome 232
glutathione S-transferase 215
caspase-9 207
P-glycoprotein 176
topoisomerase 175
lactate dehydrogenase 169
topoisomerase 164
ACS 151
catalase 146
protein kinase C 143
superoxide dismutase 142
reverse transcriptase 138
caspase-8 137
AMP-activated protein kinase 126
SPC 121
peroxidase 114
cdc2 106
urokinase-type plasminogen activator 104
phosphatidylinositol 3-kinase 102
ATPase 92
phosphoinositide 3-kinase 91
AMPK 90
alkaline phosphatase 89
thymidylate synthase 89
APC 85
NQO1 85
AMPK 82
MMP 76
DNA methyltransferase 72
enolase 70
RNA polymerase 70
glutathione peroxidase 65
GSK 65
collagenase 61
alanine aminotransferase 54
STK11 53
PAH 52
trypsin 52
thymidine kinase 51
aryl hydrocarbon hydroxylase 51
endonuclease 50
gamma-glutamyl transpeptidase 49
thrombin 47
MDR 45
transcriptase 43
IKK 43
aldehyde dehydrogenase 42
aspartate aminotransferase 42
granzyme B 41
RNase 39
aldehyde dehydrogenase 38
calcineurin 38
DNA polymerase 36
prostate-specific antigen 36
ribonucleotide reductase 36
RNase 36
aldehyde dehydrogenase 36
glutathione reductase 36
aldehyde dehydrogenase 36
aldehyde dehydrogenase 36
ribonucleotide reductase 35
phosphodiesterase 35
CYP3A4 35
PDK1 33
glyceraldehyde-3-phosphate dehydrogenase 33
demethylase 33
ACE 33
plasmin 32
beta-galactosidase 32
protein phosphatase 2A 32
BAL 31
microsomal epoxide hydrolase 31
more...
Compound
Clin 5798
DNA 5207
Dec 5046
oxygen 1273
MTT 1025
water 718
TNM 690
tyrosine 547
methionine 547
DDP 544
pyrene 530
glucose 509
calcium 409
ATP 323
iron 309
sodium 294
MEK 273
bromide 272
arginine 256
Pac 255
MDA 252
TNF 243
cysteine 237
PEG 235
phosphate 233
His 232
hydrogen 222
lysine 222
GSH 217
GSH 217
nitrogen 210
chromium 210
serine 200
iodine 200
VP-16 198
zinc 197
galactose 189
acetate 183
ethanol 178
nickel 176
copper 172
PEG 172
threonine 165
CO2 165
Asbestos 163
retinoic acid 161
creatinine 158
selenium 157
retinol 156
Paclitaxel 155
ACS 153
ACS 151
Adriamycin 146
sulfate 145
N-acetylcysteine 140
Docetaxel 139
leucine 138
SCC 136
nitric oxide 136
Gemcitabine 131
Gemcitabine 131
CBDCA 129
CBDCA 129
CPT-11 126
benzene 119
cadmium 117
Nicotine 117
fluorine 113
Curcumin 112
silver 110
Vimentin 100
alanine 100
5-FU 97
urea 96
pyrimidine 90
pyrimidine 90
ADR 87
formaldehyde 86
cAMP 86
NAD 84
more...