Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0242379 (
lung cancer
)
71,905
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
4516
Mol
3235
epidermal growth factor receptor
2431
p53
2393
tyrosine kinase
2323
EGFR
1910
caspase-3
841
AKT
781
KRAS
733
Bcl-2
704
TNM
691
ALK
638
PI3K
594
vascular endothelial growth factor
583
nodal
580
E-cadherin
561
cytokine
554
ERK
539
mTOR
532
anaplastic lymphoma kinase
522
p21
472
PD-L1
461
FDG
433
MAPK
430
catenin
425
cage
407
MET
401
PD-1
359
NMR
358
cyclin D1
348
She
347
carcinoembryonic antigen
345
CD8
343
K-ras
332
histone
330
PARP
328
ERK1
326
HER2
325
BRAF
324
ATP
321
ROS
315
MRI
313
STAT3
301
VEGF
300
matrix metalloproteinase
296
vimentin
295
Epidermal growth factor receptor
292
p38
292
IL-6
289
tumor necrosis factor
280
CD4
275
MEK
268
epidermal growth factor
266
collagen
255
CEA
253
receptor tyrosine kinase
251
caspase-9
247
TNF
243
COPD
241
MMP-9
237
Pol
231
annexin V
230
interferon
228
p16
226
proteasome
224
JNK
219
ROS1
212
glycoprotein
211
MMP-2
209
PTEN
208
CYP1A1
206
ubiquitin
206
UTR
206
survivin
205
ras
203
IFN
202
DDP
201
GSTM1
195
kit
194
Ki-67
194
more...
Disease
lung cancer
71905
cancer
31891
tumor
19028
lung carcinoma
12580
non-small cell lung cancer
7825
adenocarcinoma
6931
breast cancer
3608
metastases
3570
carcinoma
3278
squamous cell carcinoma
2973
carcinogenesis
2705
tumor growth
2264
tumorigenesis
2188
small cell lung cancer
2075
melanoma
1575
tumor progression
1524
chronic obstructive pulmonary disease
1315
prostate cancer
1252
gastric cancer
1204
colorectal cancer
1161
pneumonia
1094
mesothelioma
984
colon cancer
979
leukemia
944
primary tumor
745
tuberculosis
722
lymphoma
702
ovarian cancer
693
asthma
691
hepatocellular carcinoma
670
brain metastases
659
adenocarcinoma of the lung
576
liver cancer
563
pancreatic cancer
557
neutropenia
546
lung disease
541
bladder cancer
532
cervical cancer
523
liver cancer
499
emphysema
473
bronchogenic carcinoma
458
esophageal cancer
403
MCF
389
Hodgkin's disease
389
diabetes
386
renal cell carcinoma
376
thrombocytopenia
375
Thoracic
373
esophageal cancer
369
anemia
345
multiple myeloma
341
head and neck cancer
326
bone metastases
310
sarcoma
308
cardiovascular disease
297
pulmonary fibrosis
296
renal cancer
291
respiratory disease
278
asbestosis
273
malignant mesothelioma
268
idiopathic pulmonary fibrosis
267
hypertension
266
skin cancer
261
lymphadenopathy
259
myelosuppression
254
glioblastoma
254
myocardial ischemia
250
stroke
248
pulmonary tuberculosis
248
DDP
244
sarcoidosis
243
COPD
241
leukopenia
240
interstitial pneumonia
233
interstitial lung disease
232
pneumothorax
231
depression
231
HIV
231
glioma
223
heart disease
223
more...
Symptom
pain
669
dyspnea
578
cough
497
diarrhea
321
fatigue
320
hemoptysis
314
vomiting
286
nausea
278
anesthesia
232
chest pain
212
nausea and vomiting
193
anorexia
161
weakness
142
cachexia
111
headache
110
respiratory distress
100
shortness of breath
96
collapse
91
abdominal pain
82
discomfort
78
constipation
66
seizures
62
back pain
60
discomfort
60
starvation
55
bone pain
53
asthenia
49
clubbing
46
exhaustion
45
chronic cough
41
analgesia
40
stigma
39
angina
37
hoarseness
35
overweight
35
cancer pain
34
myalgia
33
arthralgia
33
exertional dyspnea
32
productive cough
32
numbness
31
ataxia
31
erythema
31
Ill
30
insomnia
26
wheezing
25
dizziness
25
persistent cough
23
paresthesia
23
vertigo
22
sleepiness
21
shoulder pain
21
epigastric pain
20
dysarthria
18
syncope
18
agitation
17
cerebellar ataxia
16
chills
16
hemiplegia
15
myoclonus
15
low back pain
15
decreased appetite
14
acidity
14
facial pain
14
paresis
13
blurred vision
12
memory loss
12
polyuria
11
stridor
11
dry skin
11
hyperoxia
10
cyanosis
10
tremor
10
flank pain
10
spasm
9
dysesthesia
9
hopelessness
9
flushing
9
splenomegaly
8
ophthalmoplegia
8
more...
Drug
Cardiovasc
875
Gefitinib
323
ROS
313
Erlotinib
227
Docetaxel
167
lysine
165
vitamin E
152
IL-2
147
Taxol
144
CSF
141
Monit
138
CPT-11
127
ascorbate
123
Pemetrexed
122
ROC
113
MRC
108
Bevacizumab
107
GEO
106
Vinorelbine
99
Adriamycin
94
IFN-gamma
90
Irinotecan
90
Dermatol
78
EPA
68
Tarceva
66
Mutagen
65
Vitamin A
65
G-CSF
63
Etoposide
59
TTC
56
CTX
55
Cetuximab
49
Taxotere
47
Gemzar
47
Navelbine
46
Glutathione
44
Leaf
41
Zoledronic acid
35
Tocopherol
34
ABC
33
Zoledronic acid
33
MAP
32
ETS
32
Herceptin
31
uPA
30
CTX
30
CTX
30
Gel
29
NADH
28
caffeine
28
ADM
27
Asthma
27
ADR
27
Arsenic trioxide
26
Paraffin
26
Photofrin
26
CAM
26
Silica
26
VCR
25
Alimta
24
Paraplatin
23
Asn
23
Vitamin E
22
Bortezomib
22
Imatinib
21
Retinoic acid
20
PTH
20
VCR
20
CTC
19
Parkin
18
CTC
18
Spectrum
18
Parkin
18
Sorafenib
17
ENT
16
NovoSeven
16
CCL
15
G418
15
TiO2
15
Heme
15
more...
Enzyme
ERK
3798
mitogen-activated protein kinase
1217
caspase-3
653
luciferase
618
focal adhesion kinase
508
protein kinase
428
MEK
349
PARP
347
proteasome
232
glutathione S-transferase
215
caspase-9
207
P-glycoprotein
176
topoisomerase
175
lactate dehydrogenase
169
topoisomerase
164
ACS
151
catalase
146
protein kinase C
143
superoxide dismutase
142
reverse transcriptase
138
caspase-8
137
AMP-activated protein kinase
126
SPC
121
peroxidase
114
cdc2
106
urokinase-type plasminogen activator
104
phosphatidylinositol 3-kinase
102
ATPase
92
phosphoinositide 3-kinase
91
AMPK
90
alkaline phosphatase
89
thymidylate synthase
89
APC
85
NQO1
85
AMPK
82
MMP
76
DNA methyltransferase
72
enolase
70
RNA polymerase
70
glutathione peroxidase
65
GSK
65
collagenase
61
alanine aminotransferase
54
STK11
53
PAH
52
trypsin
52
thymidine kinase
51
aryl hydrocarbon hydroxylase
51
endonuclease
50
gamma-glutamyl transpeptidase
49
thrombin
47
MDR
45
transcriptase
43
IKK
43
aldehyde dehydrogenase
42
aspartate aminotransferase
42
granzyme B
41
RNase
39
aldehyde dehydrogenase
38
calcineurin
38
DNA polymerase
36
prostate-specific antigen
36
ribonucleotide reductase
36
RNase
36
aldehyde dehydrogenase
36
glutathione reductase
36
aldehyde dehydrogenase
36
aldehyde dehydrogenase
36
ribonucleotide reductase
35
phosphodiesterase
35
CYP3A4
35
PDK1
33
glyceraldehyde-3-phosphate dehydrogenase
33
demethylase
33
ACE
33
plasmin
32
beta-galactosidase
32
protein phosphatase 2A
32
BAL
31
microsomal epoxide hydrolase
31
more...
Compound
Clin
5798
DNA
5207
Dec
5046
oxygen
1273
MTT
1025
water
718
TNM
690
tyrosine
547
methionine
547
DDP
544
pyrene
530
glucose
509
calcium
409
ATP
323
iron
309
sodium
294
MEK
273
bromide
272
arginine
256
Pac
255
MDA
252
TNF
243
cysteine
237
PEG
235
phosphate
233
His
232
hydrogen
222
lysine
222
GSH
217
GSH
217
nitrogen
210
chromium
210
serine
200
iodine
200
VP-16
198
zinc
197
galactose
189
acetate
183
ethanol
178
nickel
176
copper
172
PEG
172
threonine
165
CO2
165
Asbestos
163
retinoic acid
161
creatinine
158
selenium
157
retinol
156
Paclitaxel
155
ACS
153
ACS
151
Adriamycin
146
sulfate
145
N-acetylcysteine
140
Docetaxel
139
leucine
138
SCC
136
nitric oxide
136
Gemcitabine
131
Gemcitabine
131
CBDCA
129
CBDCA
129
CPT-11
126
benzene
119
cadmium
117
Nicotine
117
fluorine
113
Curcumin
112
silver
110
Vimentin
100
alanine
100
5-FU
97
urea
96
pyrimidine
90
pyrimidine
90
ADR
87
formaldehyde
86
cAMP
86
NAD
84
more...