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Query: UMLS:C0242379 (lung cancer)
 71,905 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Radiology and surgery are not competing but are complementary modalities in the care of patients with lung cancer. In certain areas, such as evaluation of the solitary pulmonary nodule, radiologic studies can have an important impact on patient care. Mediastinal staging with imaging studies is inexact, and CT may be most effective as a road map for more definitive surgical staging. MRI currently offers no advantages over CT in staging of the mediastinum but can be helpful in evaluation of parts of the chest not well demonstrated on axial images. A discussion of newer nuclear medicine imaging modalities is included.
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PMID:Radiologic evaluation in lung cancer: diagnosis and staging. 933 95

Surgical management of patients with concomitant resectable lung lesions and critical cardiac disease is controversial. We report a case of concomitant pulmonary and cardiac surgery via a left thoracotomy. A 67-year-old male was admitted to our hospital complaining of recurrent bloody sputum and an abnormal shadow on chest X-ray. Chest CT and MRI showed a tumor in the left lower lobe (S10), with invasion of the diaphragm. A diagnosis of squamous cell carcinoma was obtained by transbronchial lung biopsy. The patient had a history of angina pectoris, and stress testing was positive. Coronary angiography showed 90% stenosis at segment 5, suggesting a risk of perioperative or postoperative myocardial infarction. This necessitated simultaneous surgical treatment for lung cancer and ischemic heart disease. A lobectomy of the left lower lung was performed, followed by coronary artery bypass grafting (CABG), using the great saphenous vein. The postoperative course was uneventful except for the occurrence of cholecystitis. Lung cancer and ischemic heart disease can be safely treated simultaneously via a single incision, with and benefit for selected patients.
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PMID:[A case report of left postero-lateral thoracotomy for simultaneous CABG and left lower lobectomy]. 934 Dec 73

To evaluate therapeutic effect in terms of necrosis or cavity, enhanced MRI was performed in 40 lung cancer patients treated by conservative therapy. We provided the reduction ratio of the viable tumor as calculated by a volume method and a cross-sectional method. In the volume method, the volume of necrosis was subtracted from the volume of the tumor, and in the cross-sectional method, the product of the longest diameter and widest perpendicular diameter of necrosis was subtracted from the product of the longest diameter and widest perpendicular diameter of the tumor. We then examined whether we could substitute the cross-sectional method for the volume method. The reduction ratios of viable tumor calculated by the two methods were in good correlation. The limits of agreement of each method and their repeatability coefficients were considered small enough for clinical use. Therefore, we concluded that the cross-sectional method could be used in place of the volume method for clinical purposes. In evaluating therapeutic effect in terms of necrosis when using contrast-enhanced MR imaging, the reduction ratio of the viable tumor determined by the cross-sectional method can be substituted for that determined by the volume method.
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PMID:[Evaluation of therapeutic effect using enhanced MRI in lung cancer: evaluation of methods in terms of necrosis]. 939 67

Preoperative CT and Ultrasonography (US) showed adrenal tumors in four patients with lung cancer. Although metastasis of the cancer to the adrenal gland was suspected, a definitive diagnosis could not be made by CT and US alone. MRI is as ineffective as CT and US. Needle biopsy is useful if tumor cells are detected, but not unless they are discovered. Surgery, therefore, is necessary to establish the final diagnosis. (Adrenalectomy was performed on all cases, one of which had metastasis). No particular complications occurred after adrenalectomy. Adrenalectomy was considered unavoidable to determine stage and treatment policies in patients suspected of metastasis in imaging diagnosis.
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PMID:[Four cases of adrenal tumor discovered through examination before surgery for lung cancer]. 939 86

We reported a case of long survival brain metastasis and meningeal carcinomatosis from lung cancer without radiochemotherapy. A 59-year-old female admitted to our hospital suffered from headache, anorexia and nausea. Papilledema was noticed, and examinations showed a brain tumor in the left parietal lobe and cancer cells in cerebrospinal fluid. Removal of the tumor and ventriculoperitoneal shunt were performed. Pathology showed adenocarcinoma. No neurological deficit was found during the postoperative course and the patient asked for home treatment. She survived for 25 months and spent a useful life in the 15 months after the onset in spite of no radiochemotherapy for meningeal carcinomatosis. In this case, because of the slow progression of the clinical symptoms, it is considered that cancer cells in the cerebrospinal fluid space grow slowly. The first CT and MRI findings of metastatic tumor of this case showed atypical for brain metastasis. Calcifications were found in plain CT and a high intensive tumor in both T1 and T2 weighted images of MRI. Enhancement due to contrast media was very slight in both CT and MRI. We considered that these findings were related to the slow growing of cancer cells.
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PMID:[A slowly progressed case of brain metastasis and meningeal carcinomatosis from lung cancer]. 943 Jan 51

New imaging techniques, technical modifications, and new applications of established imaging techniques are discussed with regard to their cost-effectiveness in improving the end result (cure, survival, quality of life). In detecting lung cancer, two methods seem most likely to overcome the known limits of chest radiography: digital radiography with postprocessing and, for risk groups, low-dose CT. Specific diagnosis depends on detection of tiny calcifications, increased vascularization (CT, MRI) or metabolic activity (PET). Clinical staging will be improved by very short time acquisition (MRI), combination of morphologic and biological information (cross sectional techniques) and by observing metabolic activity (PET).
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PMID:[Bronchial carcinoma: new radiologic methods]. 948 May 34

Systemic idiopathic fibrosis is characterized by non-suppurative inflammatory diseases of connective tissue, mainly adipose tissue. Although, in this condition, fibrosis may develop in several organs, there have been few reports of fibrosis involving the lung or pleura. We present a case of systemic idiopathic fibrosis associated with inflammatory pulmonary lesions, mimicking lung cancer with multiple pulmonary metastases. Chest CT and MRI showed a spiculated mass around the aortic arch with localized aortic wall thickening and nodules in the lungs. Abdominal CT showed a homogeneous mass around the abdominal aorta, consistent with retroperitoneal fibrosis. Transbronchial lung biopsy of the lesion in the right mid-lung field showed only a few scattered histiocytes accompanying inflammatory and fibrotic change. There was no evidence of malignancy, necrosis, angitis or mycobacterial infection. The lesions almost completely disappeared following prednisone treatment.
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PMID:Systemic idiopathic fibrosis with inflammatory pulmonary lesions. 948 75

We report the MRI features and correlative pathologic findings of a lung cancer in a patient with progressive massive fibrosis (PMF). In this case, MRI was able to distinguish the lung cancer as a high signal intensity area, and the fibrotic mass as a low signal intensity area, on both T1-weighted and T2-weighted images when compared with muscle. MRI is potentially useful in distinguishing cancer tissue from PMF in patients with pneumoconiosis.
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PMID:Diagnosis of lung cancer in a patient with pneumoconiosis and progressive massive fibrosis using MRI. 956 34

We report a simultaneously operated case of a 68-year-old man with lung cancer accompanied with aortic arch aneurysm. Preoperative staging CT for lung cancer incidentally demonstrated another lesion in the para-aortic arch area, which was suspected to be rather a pleural or intrapulmonary lesion by enhanced CT and MRI. However, this lesion was intraoperatively diagnosed as a cystic small sized-aneurysm. After a left upper lobectomy with lymph node dissection for lung adenocarcinoma (T2N0) was performed, this aneurysm was tightly wrapped using PTFE felt during the course of one operation. The difficulty of peroperative diagnosis by CT and MRI for small sized-aneurysm is discussed, and surgical stragety for lung cancer accompanied with such an aortic aneurysm is also commented.
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PMID:[Simultaneous operation of lung cancer accompanied with aortic arch aneurysm: report of a case]. 966 70

Three patients with advanced lung cancer invading the descending aorta underwent concomitant resection under a simple temporary bypass using thin-wall metallic cannulas. In each case, invasion to the descending aorta was suspected by CT and MRI. In case 1, resection of adventitia of the aorta was performed under a temporary bypass between the left subculavian artery and the descending aorta. In case 2 and 3, tubular resection and reconstruction of the aorta were carried out under a temporary bypass between proximal site of descending aorta from involved level and distal site. Complete resections of tumors were performed in all cases. During and after operation, vital signs were stable and no ischemic disorder of lower limbs and abdominal organs were observed. Case 1 died 7 months postoperatively because of recurrence in small intestine. Case 2 and 3 are alive at present, 21 and 5 months postoperatively, respectively. This procedure has advantages of safety, simplicity, and low invasiveness, in the cases the left subcuravian artery or the descending aorta is available for proximal site of the temporary bypass.
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PMID:[Combined resection of the descending aorta under a simple temporary bypass for advanced lung cancer invading the aorta]. 1002 1


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