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Query: UMLS:C0242379 (lung cancer)
 71,905 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The diagnostic accuracy of invasion to the thoracic aorta (n = 23) and the superior vena cava (n = 22) on CT and MRI was compared to operative or autopsied finding in lung cancer. MRI was slightly superior to CT in its ability to diagnose tumor invasion to them. It is noteworthy that this invasion could be easily demonstrated by multiplanar MRI. In conclusion, because CT or MRI has diagnostic weak point respectively, these modalities should be combined adequately corresponding to the areas of tumor invasion.
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PMID:[Diagnosis of invasion to thoracic aorta and superior vena cava in lung cancer; comparative studies on CT and MRI in resected or autopsied cases]. 240 85

A case of osteoblastic skull metastasis of lung cancer is reported. A 56-year-old female patient was admitted to our hospital with complaints of headache and tumor of the right parietal bone. A plain skull X-ray showed hyperostotic feature of the right parietal bone. CT scan displayed that right parietal bone became thick and osteoblastic. Soft tissue was shown in the hyperostotic bone under MRI. An external carotid angiogram showed that the skull tumor was fed by the middle meningeal artery. The skull tumor and 2 solid intracerebral tumors were extirpated. Histological examination revealed adenocarcinoma in the skull and intracerebral lesions. The present case indicates that osteoblastic stimulating factor may be secreted by lung cancer.
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PMID:[Osteoblastic skull metastasis of lung cancer]. 259 58

The resectability of primary lung cancer depends on the extent of invasion to the mediastinum. To evaluate whether transesophageal endoscopic ultrasonography (E-EUS) could detect mediastinal invasion of lung cancer or not, this method was applied in 22 lung cancer cases in which mediastinal invasion was suspected on the basis of the chest roentgenogram and/or CT scan. An ultrasonic probe with a 5 MHz linear array transducer, 12 mm in diameter and 40 mm in length was attached to the tip of an esophagofiberscope for this study. Ultrasonographic findings were classified into four grades, grade 0; existence of a hyperechoic area between the tumor mass and the mediastinum, grade I; tumor mass in direct contact with mediastinum which appears to be normal in structure accompanied by movement of tumor mass on respiration, grade II; partial disappearance of laminar structures and changes in the mediastinal wall, with no movement of the tumor mass relative to the mediastinum, grade III; tumor invasion within the lumen of the mediastinum. Organs contained by the mediastinum include the pulmonary arteries, aorta, left atrium, pulmonary veins, superior vena cava (SVC) and the esophagus were clearly visualized in detail as real-time images, therefore more detailed information about changes in the laminar structures of walls could be obtained. The sensitivity, specificity and accuracy of E-EUS were 77.8%, 81.8% and 80.0%, respectively. E-EUS could detect mediastinal invasion more accurately than chest roentgenogram, CT or MRI. Particularly, in the SVC, descending aorta and esophagus, the longitudinal extent of tumor can be analyzed accurately. These results suggest that E-EUS can be useful to assess resectability and also to decide the surgical margin preoperatively in case of primary lung cancer in which mediastinal involvement is considered.
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PMID:[Transesophageal endoscopic ultrasonography in lung cancer involving mediastinal organs in the assessment of resectability]. 267 Nov 93

Seventy-one patients with lung tumors were studied by thoracic Ultra-low field MRI (L-MRI) and the efficacy of L-MRI is evaluated as compared with the dynamic CT scan. In staging of lung cancer, L-MRI is not useful because of its poor spatial resolution. Both T1 (Inversion recovery) and T2 (long SE) weighted images can differentiate secondary atelectasis from central tumors in 15 out of 18 (78%). This sensitivity is almost equal as that of dynamic CT. IR images with short inversion time (STIR) are particularly useful for their differentiation.
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PMID:[The clinical application of ultra-low field (0.02 T) MRI for the diagnosis of lung tumors]. 272 4

Magnetic resonance imaging and computed tomography were compared in a prospective study of 137 lung cancer patients proved by surgery or autopsy for determining the staging, evaluation of therapeutic effect and diagnosis of recurrent tumor. 1. Lung cancer staging In peripheral lung cancer, T1 and T2 relaxation times of the tumors before operation have some correlation with those of operated specimens. These relaxation times, however, are of limited nodule characterization. Hilar mass and adjacent pulmonary consolidation (obstructive pneumonia or collapse) can be distinguished on T2-weighted image (77%) and Gd-DTPA enhanced image (80%). Therefore these images help in distinguishing tumor from peripheral lung disease. In the diagnosis of tumor invasion to the heart and great vessels, MRI is superior to CT because MRI can be helpful in distinguishing true mass from heart and great vessels. As for the chest wall, MRI is more useful than CT in detecting tumor invasion especially to the thoracic inlet and superior regions. In the diagnosis of mediastinal and hilar lymphadenopathy, MRI is equivalent or slightly inferior to CT, but MRI can easily demonstrate the lymphadenopathy at subcarinal region on coronal image. 2. Evaluation of therapeutic effect in lung cancer patients treated by radiation and chemotherapy MRI patterns of therapeutic effect was divided into 3 types. It is suggested that there is some correlation between these patterns and histologic types. MRI can easily demonstrate necrotic area on T2-weighted and Gd-DTPA enhanced images. 3. Diagnosis of recurrent tumor in treated lung cancer Concerning detecting recurrent tumor after surgery or irradiation, and delineating tumor from radiation pneumonitis, T2-weighted and Gd-DTPA enhanced images are of clinical value.
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PMID:[MR imaging in the assessment of lung cancer patients: primary lung cancer staging, evaluation of therapeutic effect and diagnosis of recurrent tumor]. 279 69

Metastases are the most frequent malignant tumors of the kidney, but these lesions are of late onset in neoplastic disease. The 19 cases reported here were all investigated with various imaging techniques (CT 12 cases, ultrasonography 12 cases, urography 8 cases, angiography 2 cases, MRI 1 case). The most common primary malignancies were lung cancer, melanoma and cancer of the contralateral kidney. In this series, 8 of the lesions were solitary, and 9 were unilateral. Tumor vascularity was evaluated in 15 cases: 14 of these lesions were hypovascular. The differential diagnosis includes small cysts, lymphoma, bilateral renal cancer, multiple small abscesses and multiple small infarcts.
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PMID:[Imaging of renal metastases]. 307 17

For the early diagnosis of metastatic brain tumor, careful and long-term follow-up is important when the primary tumor has already been found. Metastatic brain tumor should be suspected whenever neurological symptoms develop in such a patient. In the cases of lung cancer or lung metastases, CT scan of brain should be taken even if the patients have no neurological symptoms, because lung cancer frequently metastasizes to the brain and other cancers metastasize to the brain via the lung. When the primary sites are unknown, primary brain tumors should be distinguished. Relatively rapid progression of symptoms including mental disturbance, multiple lesions on CT scan, lesions on chest X ray film, careful cerebral angiogram and MRI are helpful for the differential diagnosis.
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PMID:[Early diagnosis of metastatic brain tumor]. 317 5

Brain metastasis is of frequent occurrence in patients with cancer of the lung. To ascertain if brain metastasis is preventable, 34 lung cancer patients without brain metastasis were treated with 4 cycles of VM-26 plus CCNU at 4-week intervals. As a control for comparison, an equal number of lung cancer patients free of brain metastasis were treated with chemotherapy protocol which did not include VM-26 and CCNU. The patients were monitored by clinical symptoms, signs and CT or MRI scan and were followed up for 4-12 months. The results indicate that none of the VM-26 plus CCNU-treated patients developed brain metastasis while brain metastasis occurred in 7 (20.5%) of 34 control patients. The difference was statistically significant (P < 0.05).
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PMID:[VM-26 plus CCNU in the prevention of brain metastasis in lung cancer patients]. 758 6

We discuss the efficacy and limitations of CT and MRI in the assessment of the pleura and pleural cavity. With CT and MRI findings from 610 patients, we address six topics: 1) Normal anatomy of the pleural cavity, 2) Pleural effusion, 3) Pleural tumors, 4) Pyothorax, 5) Lung cancer, and 6) The pleura as a mirror of systemic diseases. CT showed specific findings of acute bleeding. MRI was sensitive enough for the diagnosis of subacute bleeding and chylothorax. In the evaluation of pleural tumors, CT and MRI revealed specific evidence of pedunculated localized fibrous tumors and lipomas. In long-standing pyothorax, it is important to detect any associated secondary malignancies. CT and MRI show as a mass penetrating the bony thorax. B-cell non-Hodgkin malignant lymphoma is the most commonly associated malignancy. The sensitivities for diagnosis of pleural extension of bronchogenic carcinoma are 80% with CT and 86% with MRI. The specificities are 89% with CT and 75% with MRI. To study the pleura as a mirror of systemic diseases, we used high resolution CT to examine 104 patients without evidence of the diseases mentioned above. Eighteen of those 104 patients were found to have pleural thickening, and all 18 were smokers. Of the 24 non-smokers, none had pleural thickening. The difference in the occurrence of pleural thickening between smokers and non-smokers was significant (p < 0.01).
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PMID:[Radiological approach to the pleura and pleural cavity with CT and MRI]. 760 23

A 48-year-old man was admitted to our hospital because of upper abdominal pain, and a cervical tumor, on Oct. 23, 1992. Chest X-ray, CT scan and MRI revealed a tumor (left-S10) and enlarged mediastinal lymph nodes. A pathological diagnosis of small cell lung cancer was made by transbronchial biopsy. Ultrasonography showed liver metastases. He received four courses of chemotherapy (Carboplatin, Ifosfamide, Etoposide). Three days after the completion of chemotherapy, his serum transaminase level was markedly increased, and he was disorientated on March 4, 1993. In spite of plasma exchange, the patient died due to hepatic failure on March 6, 1993. Fulminant hepatitis in a patient with lung cancer receiving chemotherapy is rarely reported.
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PMID:[A case of small cell lung cancer associated with fulminant hepatitis B]. 779 62


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