Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0242379 (lung cancer)
71,905 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This paper employs a comparative descriptive design to compare primary family caregivers' assessment of lung cancer patients' symptom distress with patients' own perceptions of symptom distress in the home setting. The second part describes the results of the qualitative component of this research. A convenience sample of 37 patient-family caregiver dyads completed the McCorkle and Young Symptom Distress Scale (SDS). Family caregivers' global scores were moderately correlated with patients' global scores (r = 0.71; P < 0.001). No significant differences in ratings were found for 10 of the 13 symptoms assessed. Therefore, when the patient is unable to provide a self-report of symptom distress, health-care professionals may seriously consider family caregivers' assessments of patients' symptom distress to be reasonable estimates for at least 10 of the 13 symptoms on the SDS.
...
PMID:[Perception of symptom distress in lung cancer patients: I. Agreement between patients and their caregiving relatives]. 1078 42

Our objective was to evaluate the usefulness, safety, validity and benefits of video-assisted thoracoscopic surgery (VATS) for performing pulmonary lobectomy in 24 patients with clinical NO stage I primary non-small-cell lung cancer compared with 30 patients who underwent a conventional thoracotomy. There were no significant differences in the intra-operative blood loss, duration of operation, or duration of chest tube drainage between the VATS group and the standard lobectomy group, but in this VATS' experience, patients had less postoperative pain. Numbers and distributions of dissected lymph-nodes were similar in patients whether undergoing standard thoracotomy or VATS lobectomy. We can confirm that the safety and validity of VATS are virtually identical to those of the standard thoracotomy approach in the lobectomy. However, the former technique causes less discomfort to patients and requires a shorter recovery period of laboratory data and IL-6 concentrations in thoracic drainage fluid. We conclude that VATS major lung resection is technically feasible. Stringent patient selection is important and special training is needed.
...
PMID:The role of video-assisted thoracic surgery for the treatment of lung cancer: lung lobectomy by thoracoscopy versus the standard thoracotomy approach. 1081 23

The diagnosis of lung cancer may be suspected on the basis of history, physical examination, or radiographic imaging studies. With rare exceptions, suspicions thus raised must be confirmed prior to the initiation of therapy. Advances in radiographic imaging provide an improved "roadmap" for designing diagnostic efforts. Advances in diagnostic procedures allow an easier, better tolerated, and more complete picture of the presence and extent of disease. A diagnostic algorithm using these advances provides the information necessary to design therapy while minimizing the cost, discomfort, and risk to the patient.
...
PMID:Lung Cancer: Diagnostic Techniques. 1088 99

Standard operations for lung cancer patients are generally accepted as performing lobectomy or pneumonectomy on the tumor bearing lung and ipsilateral hilar and mediastinal lymphadenectomy including subcarinal lymph nodes. Recently, minimally invasive surgery or limited resection (for example, those via VATS) has ruled our time in the field of surgery considering especially from the point of QOL. There are so many factors that cause any decline to lung cancer patients' postoperative QOL, such as operative death, postoperative cancer death, postoperative complications, long-lasting discomfort symptoms and so forth. However, a surgery, even though it is big or extensive, does not always inevitably reduce QOL for patients with lung cancer. If patients received curable resection and have got cured, it seems that they would almost all be satisfied with their postoperative QOL. Namely, at present, we do not give priority to QOL but we should give priority to curability for lung cancer surgery, if the patients have no special risk factors, which eventually would bring them almost satisfactory postoperative QOL.
...
PMID:Quality of life (QOL) versus curability for lung cancer surgery. 1148 Oct 16

Talc pleurodesis is an effective technique for the management of symptomatic malignant pleural effusions. It is assumed that a good dispersion of talc suspension contributes to the final success of this treatment. For this purpose, guidelines often advise to rotate the patient after intra-pleural instillation of the sclerosant. This prospective, randomized study analyses the dispersion of talc suspension and the overall success rate in patients with malignant effusions. After instillation of 99mTc-sestamibi-labeled talc suspension ten subjects were rotated for 1 h, while the ten other patients remained in a stable supine body position. Scintigraphic imaging was done in two directions immediately after instillation and after 1 h with a clamped drain. The overall success of the treatment was assessed 1 month after the pleurodesis. The dispersion of talc was limited and unequal in 75% of the subjects. In two patients with apparently good distribution on anterior views, the lateral views of the scintigraphy showed only limited distribution. Rotation of the patients did not influence the dispersion of sludge after 1 min or 1 h. Pleurodesis was successful in 85% of the patients after 1-month follow-up. Standard rotation protocols for patients with malignant pleural effusion do not affect the overall dispersion of talc suspension and should be abolished because of the discomfort caused to the patients.
Lung Cancer 2002 Apr
PMID:Distribution of talc suspension during treatment of malignant pleural effusion with talc pleurodesis. 1189 Oct 37

The purpose of this study is to understand the correlation of symptom distresses and coping strategies of patients with lung cancer. Seventy-three patients with non-small cell lung cancer from the cancer center or ward in the two medical centers located in northern Taiwan participated. The instruments used in this study were the Symptom Distress Scale and Coping Strategies Scale. The results of the study showed that the degree of symptom distress during the therapeutic period was mild to moderate. When patients were confronted with symptom distress, they combined problem- and emotion-focused coping strategies. Participants with higher physical symptom distress had higher psychological distress and emotion-focused coping strategy frequency. It was also found that the distress of tension-anxiety and age explained 39.4% of variance in physical symptom distresses. The physical symptom distresses and the frequency of emotion-focused coping strategy frequency explained 48.8% of variance in the psychologic symptom distresses. Finally, it is recommend that a support group be established to enable sharing of experiences and emotional support among patients.
...
PMID:Symptom distresses and coping strategies in patients with non-small cell lung cancer. 1218 99

Acute pulmonary thromboembolism is fatal if the diagnosis and treatments are delayed. Here we present a case of acute thromboembolism to the right and left pulmonary arteries after right lung lobar resection. A 52-year-old woman who admitted to our hospital with lung cancer was performed right upper lobectomy with mediastinal lymph node dissection (pT1N0M0, well differentiated adenocarcinoma). Two days after surgery, she complained sudden chest discomfort and dyspnea. The blood pressure and oxygen saturation were rapidly decreased. Because there was no lung edema or atelectasis in the chest portable roentgenogram and no ischemic change in the electrocardiogram, pulmonary thromboembolism was suspected and emergency chest computed tomography (CT) was performed. The CT showed left and right pulmonary arterial thromboembolism and immediate anti-coagulator therapy was started. Her condition was improved and chest CT, which was performed three days after the onset of the thromboembolism, showed decreased but still remained thrombus. The anti-coagulator therapy was continued and one month after the onset of the thromboembolism, thrombus was disappeared on chest CT. She is doing well 17 months after surgery. Early diagnosis and treatments are critical for the pulmonary thromboembolism.
...
PMID:[Acute pulmonary thromboembolism complicating lung lobectomy; report of a case]. 1247 69

This study aimed to examine how symptoms vary in relation to demographic characteristics (age and sex), stage of disease, histology of lung cancer, and treatment type in Korean adults with lung cancer. Symptoms were measured with the Symptom Distress Scale. A total 106 patients with a mean age of 60.9 (SD = 10.38) years participated. The results indicated that 1) overall symptom distress was more severe (mean 32.74, SD 10.75) compared to the studies reported in Western countries, and 2) among the variables, only the stage of lung cancer showed a significant relationship with total symptom distress (P < 0.05). In analyses of the individual symptoms, bowel-related symptoms showed significant relationships with sex, age, and type of treatment. The results highlight the importance of symptom management as well as the need to tailor clinical interventions according to related factors in order to maximize effective symptom management in Korean patients with lung cancer.
...
PMID:Symptom experience in Korean adults with lung cancer. 1527 94

Many patients with various forms of cancer develop sooner or later malignant pleural effusions, resulting in feelings of discomfort and reduced quality of life. Several palliative options exist, including repeated thoracocentesis and pleurodesis with a sclerosing agent. However, these "therapeutic" possibilities are not always successful and sometimes even contraindicated. Also, patients need to visit the hospital regularly or have to stay hospitalised for several days. A chronic indwelling pleural catheter could provide a simple, completely outpatient way to provide respiratory relief and improvement in quality of life in patients with malignant pleural effusions. We evaluated retrospectively the course of 17 patients with malignant pleural effusions who were treated with a chronic indwelling pleural catheter (PleurX). Eligible patients were selected in the years 2001-2003 from a single institution. In 70-80% of patients, catheter use was uncomplicated and provided significant symptom relief. Mean duration of catheter use was 2.3 (range 1-6) months. Mean fluid removal was 360 (range 150-1000 cc) per 24 h in the first weeks of treatment. Infection was seen in two (12%) patients, dislocation of the catheter in three (18%). In the final analysis, catheter use was unsatisfactory in two patients (12%). We conclude that a chronic indwelling catheter is a very useful tool in the management of recurrent malignant pleural effusions. Treatment can be accomplished completely at home, whereas complications are rare.
Lung Cancer 2005 Oct
PMID:Management of recurrent malignant pleural effusions with a chronic indwelling pleural catheter. 1599 51

The Cancer Dyspnea Scale (CDS) is a multidimensional measure of dyspnea experience, with three subscales related to sense of effort, sense of anxiety and sense of discomfort, and a total score. In this study, we evaluated the validity and reliability of a Swedish version, the CDS-S, in 99 patients with advanced lung cancer who were not receiving curative or life-prolonging treatments. Criterion-related validity was demonstrated by significant group differences in CDS-S scores when patients were stratified by dyspnea intensity, as measured by a visual analogue scale (VAS-D). Correlations between the total CDS-S score and other dyspnea scales varied between 0.63 and 0.68. Convergent validity was shown by comparing the CDS-S subscales with conceptually related measures of physical and emotional function and discomfort, and correlations ranged from 0.34 to 0.57. The CDS-S captured the psychological dimension of dyspnea better than did the VAS-D. Internal consistency of the CDS-S scales was confirmed by Cronbach's alpha coefficients ranging from 0.81 to 0.90. The CDS-S was well received by the patients and completed in 2 minutes. This study supports the CDS as a valid and reliable instrument to measure dyspnea experience in a palliative setting, well suited for use in research as well as in clinical practice.
...
PMID:Validation of a Swedish version of the Cancer Dyspnea Scale. 1663 83


<< Previous 1 2 3 4 5 6 7 8 Next >>