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Query: UMLS:C0242379 (lung cancer)
 71,905 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This paper reported 99 patients (10 with benign lesions and 89 malignant tumors) treated by tracheo-bronchoplasty. Postoperative complications occurred in 11 patients. Of whom 5 died of bronchovascular fistulas, respiratory failure, empyema, or spontaneous pneumothorax. On follow-up, among 13 patients with tracheal carcinoma treated by tracheal and/or carinal reconstructions, 4 lived for more than 5 years, 2 more than 3 years, 1 less than 1 year, and 6 died within 2 years. The survival rates of patients with bronchoplasty for lung cancer were 64.5% and 42.9% at 3 and 5 years, respectively.
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PMID:[Tracheo-bronchoplasty: a report of 99 cases]. 268 Mar 53

Among 338 adults (258 men and 80 women) presenting with spontaneous pneumothorax, there were six men with lung cancer: five squamous cell carcinoma and one oat cell carcinoma. Pneumothorax led to the diagnosis in five cases and the remaining occurred as a complication of known neoplastic disease. The average age was 67 years. We analyze these six cases, along with 46 others from the literature. In patients less than 40 years old with normal chest x-ray film findings after lung expansion, further investigation for neoplastic disease is not justified. However, heavy smoking, chronic bronchitis, bullous emphysema and incomplete lung expansion after chest drainage in patients over 40 years old are indications for cancer screening through sputum cytologic study, bronchoscopic examination and surgical exploration. The occurrence of a pneumothorax neither alters the treatment of the underlying disease nor modifies the one-year prognosis. Five-year survival is nil, suggesting that lung cancers present as pneumothorax at an advanced stage of disease.
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PMID:Spontaneous pneumothorax. A complication of lung cancer? 299 38

Primary lung cancer closely associated with a large bulla was investigated in an attempt to elucidate radiographic features of the tumor. On the basis of findings in 7 of our patients plus data on another 25 patients in the Japanese literature, we propose three major patterns of neoplasm development: nodular opacity within or adjacent to the bulla, partial or diffuse thickening of the bulla wall, and secondary signs of the bulla (changed diameter, fluid retention, and pneumothorax). As the incidence of occurrence of a pulmonary carcinoma in association with bullous disease is high, these radiographic findings will aid in early detection of a malignant lesion.
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PMID:Characteristic radiographic features of pulmonary carcinoma associated with large bulla. 305 62

Forty-nine patients with primary lung cancer were treated with fast neutron (average energy, 6 MeV) by so-called mixed therapy method at the Institute of Medical Science, University of Tokyo. Control group (Linacx-ray, 10 MV) was not randomized one, however, these patients were treated by the same chief radiotherapist (Dr. Iino) at Shizuoka Prefectural Hospital and its interval was almost the same to neutron group. The crude survival rate did not show any significant difference between them except for 1 year survival of Stage II (p less than 0.05). Radiation pneumonitis and tumor regression were thought to be almost the same. The incidence of pneumothorax (3/49) was somewhat higher than the x-ray group (3/119) but there was no significant difference. We are now planning a new mixed therapy method which has short time interval (less than 3 hours) between neutron and x-ray irradiation in expectation of decrease of shoulder in x-ray surviving fraction curve.
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PMID:[Primary lung cancer treated with fast neutron]. 641 Jan 4

Among 1,047 women fluoroscopically examined in average of 102 times during pneumothorax therapy for tuberculosis and followed up to 45 years (average = 27 yr), no increase in the total number of cancer deaths occurred when these women were compared to 717 women who received other treatments [relative risk (RR) = 0.8]. However, elevated risks of mortality from stomach cancer (RR = 2.3), rectal cancer (RR = 3.8), breast cancer (RR = 1.2), lung cancer (RR = 1.8), and leukemia (RR = 1.2) were observed, but none was statistically significant and all were based on very small numbers of deaths. These increases were balanced by decreases of genital cancer (RR = 0.2), pancreatic cancer (RR = 0.9), lymphoma (RR = 0.6), and all other cancers (RR = 0.1). Average cumulative absorbed doses were 110 rads for the lungs, 33 rads for the trunk, 13 rads for the active bone marrow, and 7 rads for the stomach. The following upper levels of excess risk could be excluded with 95% confidence: 3.5 deaths/10(6) woman-year (WY)-rad for lung cancer, 4.8 deaths/10(6) WY-rad for lymphoma, and 12 deaths/10(6) WY-rad for leukemia. These findings indicated that the carcinogenic effect of multiple low-dose X-ray exposures was not greater than that currently assumed.
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PMID:Cancer mortality in women after repeated fluoroscopic examinations of the chest. 693 30

A review of cases of lung cancer treated in a hospital department over a period of 6 years demonstrated the presence of an associated pneumothorax in 3 patients: in 2 cases this was the initial manifestation of the lung cancer, while in the third case it developed after the diagnosis had been established. In most of the published cases (less than 100) the lesion was already present on initial radiological images after reexpansion. In very rare cases, recurrent pneumothoraces or ones difficult to reexpand, without visible lesions on chest radiography after expansion, were provoked by a lung cancer. Because of the low incidence in this group of patients, it appears unjustified to submit them to an exhaustive search for a pulmonary neoplasm.
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PMID:[Pneumothorax and cancer of the lung. Apropos of 3 cases]. 716 96

Pneumothorax is a rare manifestation of lung cancer. It has been reported to date in a total of about 25 patients. We describe two patients with spontaneous pneumothorax as the first sign of a bronchial carcinoma.
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PMID:Spontaneous pneumothorax as first symptom in bronchial carcinoma. 738 26

The present experimental study shows that anticancer agents may accumulate around electrodes placed in saline and in lung when the electrodes are charged with direct electric current. We also observed that electrochemical therapy (ECT) in combination with chemotherapy was more effective for treatment of localized tumours (human lung cancer PC-13 transplated to nude mice) than was ECT or systemic chemotherapy alone. In a clinical study, 26 patients (27 lesions) received ECT with or without systemic chemotherapy. We observed a decrease in tumour size in more than 70% of the cases, and in two cases the use of ECT alone resulted in complete regression of the tumour. In one case there was an increase in tumour size. The main side-effects observed during treatment of lung cancer was pain during treatment, fever after treatment, and pneumothorax. We conclude that ECT may be effective in controlling localised tumours. The clinical use of ECT is, however, associated with several problems and the mechanism of this treatment has not yet been completely established.
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PMID:Clinical and experimental studies of anti-tumoural effects of electrochemical therapy (ECT) alone or in combination with chemotherapy. 753 Oct 23

Thoracoscopy was performed in a total of 424 patients at our institute from January 1970 to December 1993. The indications for thoracoscopy were pneumothorax (121 cases), primary lung cancer (98 cases), mediastinal tumor (45 cases), metastatic lung tumor (23 cases), pleuritis (35 cases), diffuse lung disease (38 cases), tuberculosis (20 cases), benign lung tumor (10 cases), and other (34 cases). By 1990, diagnostic thoracoscopy had been performed in 383 patients. Since 1991, thoracoscopy has been used therapeutically for spontaneous pneumothorax (24 cases), mediastinal and chest wall tumors (9 cases), pulmonary nodules (2 cases), and others (8 cases). Findings useful for diagnosis were obtained in 326 cases and biopsy was performed in 173 cases. Thoracoscopy was especially useful in the diagnosis of diffuse lung disease, pleuritis, and small pulmonary nodules. Recent advances in endoscopic equipment and refinement of thoracoscopic techniques have expanded the application of this procedure. Our experience indicates a markedly expanded role for thoracoscopy in the diagnosis and treatment of thoracic diseases, with less postoperative morbidity.
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PMID:[Thoracoscopic observation and diagnosis in cases of pleural, mediastinal, and pulmonary lesions]. 760 26

Recently developed thoracoscopic surgical equipment and related instruments have enabled us to perform two groups of advanced thoracoscopic surgical procedures. Group 1: procedures formerly performed by open thoracotomy, and group 2: procedures performed by thoracoscopic surgery only. Group 1 includes bullectomy for spontaneous pneumothorax, wedge resection for lung nodules, resection of benign tumors of the mediastium or chest wall, lung lobectomy, and resection of giant bullae. Because thoracoscopic surgery is minimally invasive, intrathoracic surgical procedures should be performed by thoracoscopic surgery if the results are the same. Group 2 consists of surgery in patients with poor pulmonary reserve and laser ablation of the bullous lung in advanced emphysema. Until recently, surgical intervention was not an option in the patients in groups 2 because of the invasiveness of open thoracotomy. Thoracoscopic surgery allows resection of tumors in early stage lung cancer in patients with poor pulmonary reserve. Severely emphysematous lungs can be ablated with a laser and shrunk, to normalize pulmonary compliance, residual volume and total lung capacity, and thus relieve symptoms.
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PMID:[Thoracoscopic treatment of intrathoracic diseases]. 760 27


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