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Query: UMLS:C0242379 (lung cancer)
 71,905 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

RI-angiography with 99mTcO4- was carried out using a scintillation camera with a digital minicomputer for the purpose of imaging of bronchial blood flow in various lung diseases, and as application of dual radioisotope techniques, other imagings such as tumor imaging with 197HgCl2 or 67Ga-citrate and/or perfusion imaging with 99mTc-MAA, were performed simultaneously in patients remaining the same position, too. The image as a iso-count map extracted out of the image of 197HgCl2, 67Ga-citrate or 99mTc-MAA, was superimposed to the brightness image of RI-anigogram (aortic phase). By these procedures, the image of bronchial blood flow were obtained in some patients with lung cancer, pulmonary tuberculosis, lung abscess, and chronic bronchitis. The dual radioisotope techniques using RI-angiography and the other imaging were useful to make isotope diagnosis of lung diseases more reliable, and the image superimposition methods using RI-angiogram and the image of tumor or perfusion, were useful to improve anatomic orientation of the former.
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PMID:[Imaging of the bronchial blood flow usingg RI-angiography--study on its procedure and application of dual radioisotope technique (author's transl)]. 55 74

Since 1963 in the All-Union Research Institute of Clinical and Experimental Surgery 1445 patients with malignant lung tumors were operated upon, in 44 patients (3%) rare tumors were observed. The source of the rare tumors origination was: epithelium--in 14 cases, connective tissue--in 3, vessels--in 10, smooth muscle--in 3, nervous tissue--in 2, hemopoietic tissue--in 6, pleura--in 4. In one observation the tumor showed a mixed genesis, and in one case it exhibited a dysembryogenetic character. Rare malignant lung tumors (especially sarcomas, plasmocytomas, mesotheliomas) show a definite specificity of clinico-roentgenological manifestations, that should be taken into accout in establishing the differential diagnosis. The ultimate diagnosis was most frequently put after histological assay of the removed neoplasm. A total of 46 operations were performed (two patients were repeatedly operated upon). An extent of surgical interventions in rare malignant tumors is determined by the size, type of the tumor growth and its localization, and it is largely identical to that in lung cancer.
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PMID:[Rare malignant tumors of the lungs (44 cases)]. 58 13

Retrospective data on dietary habits, employment history and tobacco use were obtained from 569 bladder cancer patients and 1025 age-matched controls admitted to Roswell Park Memorial Institute. Sex-adjusted relative risks revealed increases in risk for lower levels of an index of vitamin A intake. A similar pattern of risk elevation was associated with infrequent milk and carrot intake. Some elevation of risk was found for heavy coffee drinking but the apparent protective effect for milk consumption was not found to be a spurious result of lower coffee intake. Neither was the role of vitamin A explained by its relationship with smoking or employment in high risk occupations. Some association of bladder cancer with infrequent consumption of cruciferous vegetables was also observed. The findings of this investigation are consistent with tumor inhibition by retinoids in animal studies and the low risk associated with vitamin A in epidemiologic studies of lung cancer.
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PMID:Dietary risk factors in human bladder cancer. 58 94

A new era dawned in 1940 when Batson published the theory that the vertebral venous system plays an important role in cancer carriage. He emphasized that this route comes into play with any natural movement such as coughing. Now, cough is a prominent feature of lung cancer. Therefore, this tumor is optimally positioned for utilizing the vertebral venous route of spread. However, when three major distribution patterns of lung cancer are examined critically, expectations from Batson's theory are not confirmed. If this paradox is recognized and explained, the prospects for solving the mysteries of human cancer metastasis will probably improve.
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PMID:Paradoxical position of vertebral veins in cancer carriage. 59 85

To evaluate the effect of operative stress on a tumor growth, thoracotomy and/or laparotomy were performed 48 hours after the intraperitoneal inoculation of Sato lung cancer cells in Donryu rats. The survival time and the spread of the tumor were examined. Thoracotomy and laparothoracotomy reduced significantly the survival time of the inoculated rats as compared with the control but no significant difference was observed between the two test groups subjected to operative stress. No difference was observed in the spread of the tumor between the test groups and the control. These results indicated that the operative stress increased only the number of metastatic foci and did not change the characteristics of the tumor cells.
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PMID:Enhancing effect of thoracotomy and/or laparotomy on the growth of ascitic tumor in rats. 60 96

In the course of a screening program for lung cancer detection which has been going on for several years, 2432 male risk persons, aged 42-67, were examined cytologically in 1974 and 1975. The annual rate of incidence of lung cancer in this population is unknown. We estimate it at 3-4%. From two sputa of each patient we screened one specimen. 24.7% of the sputa were unsatisfactory. In the remaining preparations there were neither tumor cells nor cells suspicious for cancer. This result is discussed in view of the experiences of other authors, that the sensitivity of cytological screening for lung cancer is 33-38%. Recommendations are given for increasing the number of detected cases.
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PMID:[The value of sputum cytodiagnosis as a screening method for lung cancer detection--results of a study (author's transl)]. 61 45

In a prospective study of 6,027 older men screened every six months for ten years by means of chest photofluorograms and questionnaires regarding symptoms, 121 developed lung cancer after the first examination. Eighty-five men with lung cancer had the opportunity to be screened eight times before the tumor was detected by chest x-ray film, but only 33 actually reported that often. These 33 men were compared with matched controls for symptoms before the neoplasm was detected radiologically. The common symptoms of expectoration and chronic cough showed a significant increase in frequency over time in the cases of cancer, while only expectoration showed a slight increase in the controls. Uncommon symptoms more suggestive of lung cancer (hemoptysis and worsening cough) occurred in only four men prior to detection of cancer. Symptoms are seldom useful in the detection of occult lung cancer, but the appearance of expectoration and chronic cough in older male smokers should raise a suspicion of this disease.
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PMID:The Philadelphia Pulmonary Neoplasm Research Project. Symptoms in occult lung cancer. 62 May 58

An analysis of the results of bronchial tumor biopsy performed in 200 lung cancer patients is reported. Morphological verification proved feasible in 193 of 200 patients. Biopsy and puncturing of the tumor are found to be most advantageous technics for the material take during bronchoscopy. Contrary to biopsy, an efficiency of transbronchial puncturing is not affected by the character of tumor growth and its morphological structure. A combined use of biopsy and puncture makes it possible to increase the percentage of morphologically supported diagnosis of pulmonary cancer. Transbronchial puncturing is also an efficient maneuver for detection of cancer recurrence in the bronchial stump and a residual tumor after conservative therapy. Endoscopic signs of the peribronchial pattern of tumor growth are absolute indications to its puncture.
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PMID:[Puncture of a bronchial tumor in the bronchoscopic diagnosis of lung cancer]. 63 80

In 110 lung cancer patients the authors have determined the rate of separate distension of the lung and chest (DL--C), and in 60 of them radiopneumography with Xe133 was employed. All patients were subdivided into 3 groups: I--those suffering chronic concomitant lung affections, II--those with acute pulmonary diseases in the anamnesis, III--those showing no signs of concomitant pathology. It was found that the previous diseases (pneumonia, acute bronchitis) render no significant effect on the external respiration function (as evidenced by radiopneumographic findings). Whereas concomitant pathology (chronic bronchitis, chronic pneumonia, etc.) would aggravate the function considerably, that is especially pronounced in central tumor localization. In patients of the group I and II DL--C was found to be markely reduced, that may be due to asymptomatic pleurofibrosis in the group II. To estimate the possibilities of surgical treatment for lung cancer, a detailed complex diagnosis of concomitant nonspecific pulmonary pathology seems to be absolutely necessary.
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PMID:[Role of nonspecific accompanying pulmonary pathology in altering the external respiratory function in lung cancer]. 63 82

Using radiobiochemical methods "in vitro" by means of determining hormone production in blood serum, the authors studied the functional state of the hypophysis, adrenal glands, the pancreas and thyroid in 51 patients with lung cancer: stage I--in 8 patients, II--in 7, III--in 23 and IV--in 13. Histological structure: adenocarcinoma--in 9, epidermoid cancer--in 29, undifferentiated cancer--in 5. The analysis indicated that the hormonal disbalance in the organism of lung cancer patients is not evidenced by secondary clinical manifestations of the disease (atelectasis, suppuration, etc), there being a number of general regularities in the response of the hypophysis, adrenal glands, the pancreas and thyroid depending on the stage. This dependence shows a sinusoidal pattern maximum pronounced in stage I. Some common regularities in the endocrinous response of the hypophysis and adrenal glands are observed in different histostructure of the tumor, the response increasing in the following sequence: adenocarcinoma, epidermoid, undifferentiated cancer.
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PMID:[Endocrine system reaction in relation to the clinical manifestations of lung cancer]. 63 84


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