Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0242339 (dyslipidemia)
 13,927 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
insulin 4434
HDL 1498
Sep 834
leptin 401
Mol 400
adiponectin 368
C-reactive protein 354
hemoglobin 280
apolipoprotein B 264
peroxisome proliferator-activated receptor 261
renin 235
apolipoprotein 227
LDL receptor 192
gut 191
lipoprotein lipase 189
tumor necrosis factor 184
TNF 169
cytokine 162
HMG-CoA reductase 162
albumin 155
ATP 149
IL-6 141
reductase 138
peroxisome proliferator-activated receptor gamma 137
proprotein convertase subtilisin/kexin type 9 131
fibrinogen 126
adipokine 114
superoxide dismutase 105
PPAR 103
apolipoprotein E 100
glucagon 98
apoE 96
CRP 94
collagen 94
endoplasmic reticulum 87
nuclear receptor 86
Lp(a) 85
cholesteryl ester transfer protein 85
chronic renal failure 84
AMP-activated protein kinase 84
alanine aminotransferase 78
fatty acid synthase 78
resistin 74
catalase 74
plasminogen activator inhibitor-1 73
aspartate aminotransferase 71
interleukin-6 71
Peroxisome proliferator-activated receptor 70
AMPK 68
epididymal 67
ACE 64
insulin receptor 62
protease inhibitor 61
CD36 58
low-density lipoprotein receptor 58
apolipoprotein A-I 57
hepatic lipase 57
She 56
GSH 56
angiotensin receptor 56
Adiponectin 56
calcium channel 56
A-I 55
angiotensin II 55
Pol 54
IRS-1 54
vascular endothelium 52
CD4 51
growth hormone 50
Leptin 50
thyroid hormone 48
lipase 48
LDLR 47
glutathione peroxidase 46
NIDDM 46
mTOR 46
angiotensin II receptor 45
TNF-alpha 45
LPL 45
apoB-100 45
AST 45
SREBP-1c 43
Men 43
ABCA1 43
GLP-1 receptor 42
apolipoprotein A1 42
acetyl-CoA carboxylase 41
farnesoid X receptor 41
endothelial nitric oxide synthase 41
MRI 41
alkaline phosphatase 40
peptidase 40
cytochrome P450 40
peroxisome proliferator-activated receptor alpha 40
APOC3 40
plasminogen activator inhibitor 37
sterol regulatory element-binding protein 37
nitric oxide synthase 36
CETP 36
microsomal triglyceride transfer protein 36
SBP 35
ghrelin 35
lipopolysaccharide 35
TLR4 35
creatine kinase 34
PPAR-alpha 34
AKT 33
tumor necrosis factor alpha 32
calcineurin 32
ROS 32
GLP-1 32
microsomal 31
Fibroblast growth factor 21 31
glucose transporter 31
CHD 31
serum albumin 31
APOE 31
CYP7A1 31
monocyte chemoattractant protein-1 30
GFR 30
vascular endothelial growth factor 30
SREBP-2 29
CAD 29
eNOS 29
HSD1 29
glucocorticoid receptor 29
visfatin 29
stearoyl-CoA desaturase 28
SOD 28
SREBP-1 28
lactate dehydrogenase 28
DPP 28
peroxisome proliferator activated receptor 27
FAS 27
antioxidant enzyme 27
interleukin 6 27
parathyroid hormone 27
MCP-1 27
inducible nitric oxide synthase 27
ACC 27
ANOVA 26
MAPK 26
STZ 26
IL-10 26
vascular cell adhesion molecule-1 26
APOA5 25
carnitine palmitoyltransferase 25
SCD1 25
EPA 24
San 24
LCAT 24
insulin-like growth factor 24
endothelin-1 24
aP2 23
Lipoprotein lipase 23
DM2 23
PI3K 23
thrombin 23
protein kinase B 23
uncoupling protein 1 22
more...
Disease
dyslipidemia 13927
hypertension 5362
diabetes 5158
obesity 4625
cardiovascular disease 2888
metabolic syndrome 2742
type 2 diabetes 2395
atherosclerosis 2083
hyperglycemia 1351
glucose intolerance 871
coronary heart disease 812
coronary artery disease 808
stroke 739
fatty liver 696
hyperlipidemia 677
hyperinsulinemia 638
hypercholesterolemia 591
myocardial infarction 566
renal disease 496
cancer 439
abdominal obesity 438
HIV 390
heart failure 318
polycystic ovary syndrome 254
myocardial ischemia 245
plaque 240
lipodystrophy 217
proteinuria 215
vascular disease 210
Nonalcoholic fatty liver 207
depression 206
atherosclerotic cardiovascular disease 202
heart disease 173
liver disease 171
alcoholic fatty liver 171
AIDS 166
hyperuricemia 166
renal failure 157
cirrhosis 156
microalbuminuria 152
chronic renal failure 150
diabetic nephropathy 148
osteoporosis 147
obstructive sleep apnea 140
anemia 137
immunodeficiency 136
metabolic disorder 135
type 1 diabetes 135
hypothyroidism 122
Alzheimer's disease 118
rheumatoid arthritis 117
ventricular hypertrophy 115
ischemia 115
hepatocellular carcinoma 112
dementia 111
schizophrenia 110
retinopathy 106
psoriasis 105
acute myocardial infarction 104
essential hypertension 101
hyperandrogenism 100
cardiovascular risk factor 100
malnutrition 93
neuropathy 91
prediabetes 91
hypoglycemia 89
congestive heart failure 87
chronic disease 84
tumor 83
diabetic retinopathy 80
cognitive impairment 79
arteriosclerosis 75
systemic lupus erythematosus 75
sleep apnea 75
erectile dysfunction 72
osteoarthritis 72
chronic liver disease 72
nephrotic syndrome 71
hyperhomocysteinemia 70
peripheral vascular disease 69
Syndrome 69
infertility 65
breast cancer 64
syndrome X 64
glomerulosclerosis 60
Cushing's syndrome 59
Endothelial dysfunction 59
asthma 59
renal insufficiency 58
gestational diabetes mellitus 58
arthritis 58
gout 57
GSH 57
cardiomyopathy 57
lipoatrophy 55
hypogonadism 53
Chronic kidney disease (CKD) 51
lipid disorder 50
preeclampsia 50
uremia 50
unstable angina 49
pancreatitis 49
morbid obesity 48
myopathy 48
LDLR 47
gallstones 47
hepatitis C 46
vitamin D deficiency 46
anovulation 45
hyperphagia 44
prostate cancer 44
chronic obstructive pulmonary disease 43
aggression 41
infectious diseases 41
endocrine disorder 39
cholestasis 39
liver fibrosis 38
cholesterolemia 38
renal impairment 37
bipolar disorder 37
psoriatic arthritis 35
overnutrition 35
lupus 34
hyperlipoproteinemia 34
psychosis 34
Best 34
gastroesophageal reflux disease 33
hyperparathyroidism 31
cerebral infarction 31
peripheral neuropathy 31
skin disease 30
carcinoma 30
mental illness 30
acanthosis nigricans 29
blindness 29
hypercortisolism 29
transient ischemic attack 28
Familial combined hyperlipidemia 28
FAS 28
cold 28
diabetic neuropathy 28
Overweight and obesity 28
acute pancreatitis 27
sexual dysfunction 27
intermittent claudication 27
generalized lipodystrophy 26
acne 26
carcinogenesis 25
systolic hypertension 24
hepatitis 24
diabetic cardiomyopathy 24
hyperthyroidism 24
DM2 23
colorectal cancer 23
bone disease 23
pneumonia 22
systemic disease 22
autoimmune disease 22
periodontitis 22
virus infection 21
more...
Symptom
overweight 629
angina 113
pain 83
flushing 48
fatigue 40
chest pain 35
weakness 34
diarrhea 28
myalgia 28
hepatomegaly 27
nausea 21
headache 19
seizures 18
abdominal pain 18
vomiting 17
starvation 17
cachexia 16
dyspnea 15
anesthesia 14
sleepiness 14
discomfort 13
syncope 13
discomfort 12
back pain 11
snoring 10
insomnia 10
constipation 10
anorexia 10
cough 9
dizziness 9
collapse 9
polyuria 8
vertigo 8
arthralgia 7
Ill 6
exhaustion 6
hepatosplenomegaly 6
hunger 6
hypercapnia 6
thinning 5
spasm 5
menopausal symptoms 5
asthenia 4
dysarthria 4
erythema 4
stigma 4
Decreased activity 4
shortness of breath 4
polydipsia 4
splenomegaly 4
exertional angina 4
peri-menopausal 4
abdominal discomfort 3
leg pain 3
lethargy 3
ataxia 3
ataxic gait 3
numbness 3
agitation 3
Depressive symptoms 3
hypothermia 3
acute stress 3
memory loss 3
respiratory distress 3
analgesia 3
epigastric pain 3
hemiplegia 3
functional recovery 2
chills 2
colic 2
renal colic 2
dark urine 2
exertional dyspnea 2
oliguria 2
neurological disability 2
presyncope 2
pallor 2
Cushingoid 2
Cushingoid 2
paresis 2
shoulder pain 2
dystonia 2
atypical chest pain 2
bitter taste 2
hot flushes 2
acidity 2
Wind 2
bloating 2
HSA 2
chest tightness 2
consciousness disturbance 2
hypotonia 2
masculinization 2
personality change 1
leg edema 1
hypoproteinemia 1
Neuropathic pain 1
asynergy 1
bone pain 1
jaw pain 1
decreased appetite 1
lightheadedness 1
urinary frequency 1
acute abdomen 1
swollen joints 1
Male sexual dysfunction 1
Appetite suppression 1
orthopnea 1
Abdominal tenderness 1
nasal congestion 1
paraparesis 1
pleuritic chest pain 1
apathy 1
aphagia 1
stomach pain 1
physical appearance 1
No adverse effect 1
chronic back pain 1
body pain 1
tense 1
Multimorbidity 1
Postoperative pain 1
cyanosis 1
Stiffness 1
blepharospasm 1
abnormal breathing 1
loss of balance 1
despair 1
regurgitation 1
toe pain 1
tinnitus 1
dysuria 1
left upper quadrant pain 1
tremor 1
enuresis 1
paresthesia 1
ketonuria 1
abnormal gait 1
low back pain 1
right lower quadrant pain 1
pelvic pain 1
Spots 1
productive cough 1
dry eye 1
exertional chest pain 1
hemoptysis 1
myoclonus 1
night sweats 1
hip pain 1
hot flashes 1
livedo 1
Drug
Cardiovasc 423
niacin 209
Simvastatin 54
Dermatol 53
vitamin E 50
Rosuvastatin 48
Fructose 45
Ezetimibe 45
Dial 41
ROS 32
ascorbate 27
ADM 23
Monit 23
EPA 19
Bezafibrate 18
Rosiglitazone 18
Rimonabant 17
Kenyan 17
ROC 17
Glucagon 16
Gemfibrozil 15
Lovastatin 15
Orlistat 15
Pravastatin 14
lysine 13
Angiotensin II 11
Asthma 11
MAP 11
ALA 11
Growth hormone 10
Growth hormone 10
NAH 10
Leaf 9
Tacrolimus 9
Bifidobacterium 9
Vitamin E 9
PTH 8
Albumin 8
Nephron 8
caffeine 7
nitroglycerin 7
ABC 6
NADH 6
ATV 6
Retinoic acid 6
Nephron 6
Valsartan 6
Liraglutide 6
Troglitazone 6
Lescol 5
IL-2 5
Glycyrrhiza 5
Infliximab 5
Exenatide 5
Infliximab 5
Aloe 5
Clofibrate 5
Neoral 5
Lipidex 5
Lipitor 4
citric acid 4
DHT 4
Clopidogrel 4
Lipitor 4
Colesevelam 4
Tocilizumab 4
DHT 4
EPI 4
Lescol 4
Cilostazol 4
Metreleptin 4
Olmesartan 4
Captopril 4
TAK 4
TAT 4
NVP 4
Lipitor 4
TAC 4
Rosuvastatin calcium 4
Ramipril 3
EE2 3
Tesaglitazar 3
Honey 3
Ginseng 3
Portal 3
AHF 3
CSF 3
Torcetrapib 3
IFN-gamma 3
Spectrum 3
Rutin 3
Nitric Oxide 3
Creosote 3
lactose 3
CAM 3
Check 3
Ethanol 3
Vitamin A 3
CVA 3
Vitamin K 3
Digitalis 2
Asn 2
Bexarotene 2
Febuxostat 2
DM1 2
Ramelteon 2
Sevelamer 2
Lacidipine 2
DEX 2
ENT 2
PMPA 2
Jujube 2
Darapladib 2
Glycerol 2
Apomorphine 2
Alanine 2
Red ginseng 2
Adenosine triphosphate 2
Benfotiamine 2
Ciprofibrate 2
metformin hydrochloride 2
Prednisolone 2
GHRP 2
Sesamol 2
G-CSF 2
Humalog 2
Gliclazide 2
MRC 2
Opium 2
Olive oil 2
Tenofovir disoproxil fumarate 2
ETA 2
IL-1ra 2
Lacidipine 2
Muraglitazar 2
CIA 2
ADR 2
Polydextrose 2
CTA 2
Ranitidine 2
Everolimus 2
Imatinib 2
Omacor 2
CCL 2
Vardenafil 2
Ortho Tri-Cyclen 1
CTX 1
Aliskiren 1
Reboxetine 1
Emodin 1
Galactose 1
Ketotifen 1
MDS 1
AZT 1
Etravirine 1
Norvasc 1
9-THC 1
Rokitamycin 1
Vitamin B 1
Lactase 1
more...
Enzyme
renin 235
lipoprotein lipase 190
alanine aminotransferase 154
AMP-activated protein kinase 142
superoxide dismutase 128
aspartate aminotransferase 113
lipase 96
ACE 94
mitogen-activated protein kinase 85
catalase 81
AMPK 70
AMPK 68
protein kinase 68
3-hydroxy-3-methylglutaryl coenzyme A reductase 60
glutathione peroxidase 47
creatine kinase 47
LPL 45
AST 45
reverse transcriptase 45
acetyl-CoA carboxylase 41
alkaline phosphatase 40
protein kinase C 40
calcineurin 38
subtilisin 38
proprotein convertase 38
ERK 37
CPT 34
CAD 29
tissue plasminogen activator 29
CYP7A1 29
CAD 29
CAD 29
phosphoenolpyruvate carboxykinase 28
furin 28
lactate dehydrogenase 28
NADPH oxidase 27
peroxidase 26
luciferase 25
paraoxonase 25
phospholipase A2 24
cholesterol acyltransferase 24
gamma-glutamyl transpeptidase 23
thrombin 23
paraoxonase 23
NO synthase 22
focal adhesion kinase 22
hormone-sensitive lipase 22
NADPH oxidase 20
phosphoenolpyruvate carboxykinase 20
phosphoenolpyruvate carboxykinase 20
glucokinase 20
phosphatidylinositol 3-kinase 18
11beta-hydroxysteroid dehydrogenase 18
lecithin:cholesterol acyltransferase 18
ATPase 18
proteasome 16
alpha-glucosidase 15
glucose-6-phosphatase 15
CYP3A4 14
phosphodiesterase 14
diacylglycerol acyltransferase 13
3-hydroxy-3-methylglutaryl-CoA reductase 12
hexokinase 12
CPT 12
CPT 12
caspase-3 12
glutathione reductase 12
acyl-CoA oxidase 12
xanthine oxidase 11
GSK 11
thromboplastin 11
ACS 9
ceruloplasmin 9
glutathione S-transferase 9
plasmin 9
pyruvate kinase 9
aldose reductase 9
MAP 8
heme oxygenase 8
aldehyde dehydrogenase 8
NOS 8
acetylcholinesterase 7
APC 7
P-glycoprotein 7
RNase 7
RNase 7
cholinesterase 7
methylenetetrahydrofolate reductase 6
malate dehydrogenase 6
PDK1 6
methylenetetrahydrofolate reductase 6
farnesyltransferase 6
RNA polymerase 6
MEK 6
dipeptidyl peptidase IV 5
complex I 5
HIV-1 protease 5
kallikrein 5
collagenase 5
caspase-1 5
HSD 5
transcriptase 5
phosphoinositide 3-kinase 5
xanthine dehydrogenase 5
acid phosphatase 4
phospholipase C 4
succinate dehydrogenase 4
TAT 4
aldehyde dehydrogenase 4
soluble epoxide hydrolase 4
glyceraldehyde-3-phosphate dehydrogenase 4
glucose-6-phosphate dehydrogenase 4
TOR 4
phosphorylase 4
sucrase 4
aldehyde dehydrogenase 4
CD10 4
IKK 4
aldehyde dehydrogenase 4
invertase 4
SPT 4
aldehyde dehydrogenase 4
lipoxygenase 4
ribonuclease 4
AMP-activated kinase 4
ribonuclease 4
urokinase-type plasminogen activator 4
citrate synthase 4
pyruvate dehydrogenase 4
endonuclease 4
AGT 3
uricase 3
PDE 3
phospholipase D 3
prostacyclin synthase 3
cholesterol esterase 3
glyceraldehyde-3-phosphate dehydrogenase 3
glyceraldehyde-3-phosphate dehydrogenase 3
glyceraldehyde-3-phosphate dehydrogenase 3
matrix metalloproteinase 9 3
NQO1 3
MDR 3
glyceraldehyde-3-phosphate dehydrogenase 3
fatty acid desaturase 3
angiotensin-converting enzyme 2 3
trypsin 3
matrix metalloproteinase 2 3
ACAT 3
MMP 3
flavin-containing monooxygenase 3
caspase-9 3
asparaginase 3
MMP-3 3
fructose 1,6-bisphosphatase 3
prostate-specific antigen 3
arginase 3
sterol carrier protein 3
15-lipoxygenase 3
carboxylesterase 2
transketolase 2
more...
Compound
glucose 2761
Clin 1329
Dec 969
Cardiol 687
Insulin 453
Cholesterol 319
calcium 280
creatinine 250
water 249
oxygen 242
nitric oxide 189
DNA 187
TNF 169
sodium 154
ATP 149
nicotinic acid 133
aldosterone 119
homocysteine 118
vitamin D 102
acetate 99
Statin 96
nicotinic acid 94
salt 94
phosphate 89
nicotinic acid 81
nicotinic acid 81
Atorvastatin 68
arginine 64
Fenofibrate 64
ethanol 60
urea 59
GSH 58
GSH 58
Metformin 55
Metformin 55
Diabetol 53
Diabetol 51
CoA 50
nitrogen 49
Pac 49
iron 46
Fructose 45
glycerol 45
silver 44
Dial 41
TSH 40
Thyroid 39
potassium 37
alanine 37
His 36
sulfate 36
palmitic acid 34
STZ 33
zinc 33
Optimal 32
ASA 31
nicotinamide 31
MDA 29
palmitic acid 28
alloxan 28
serine 28
DPP 28
tyrosine 28
hydrogen 27
phosphorus 26
nitrate 26
cAMP 26
selenium 26
Angiotensin II 24
ADP 23
methionine 23
L-carnitine 23
Vitamin D 23
AMP 23
threonine 23
leucine 22
HMG-CoA 22
copper 22
ADP 21
DBP 21
ADP 21
Estrogen 21
DHA 21
DBP 21
chromium 21
Oil Red O 20
FFA 20
ALP 20
glutamate 20
Testosterone 19
Testosterone 19
cysteine 19
Estrogen 19
Oil Red O 19
Resveratrol 19
prostacyclin 19
EPA 18
Pioglitazone 18
retinol 18
Fibrinogen 17
NADPH 17
NADPH 17
Androgen 17
Berberine 17
retinoic acid 16
Glucagon 16
THP 16
NAD 15
DHA 15
THP 15
DHA 15
galactose 15
lysine 15
AHA 15
coenzyme Q10 14
acetic acid 14
TOF 14
Curcumin 13
PMA 13
Lovastatin 13
Olanzapine 13
Melatonin 13
Rapamycin 13
ACTH 13
CO2 12
CPT 12
AGE 12
FK506 12
gallic acid 12
NAD 12
Quercetin 12
CPT 12
GSSG 11
SDS 11
Pravastatin 11
ethyl acetate 11
noradrenaline 11
glutamine 11
Uric acid 11
iodine 11
MAP 11
Ang II 11
tryptophan 11
cadmium 11
cGMP 10
Retinal 10
tryptophan 10
Vitamin E 10
propionic acid 10
Mg2+ 10
manganese 10
acetyl-CoA 10
tryptophan 10
Sodium 10
tryptophan 10
propionic acid 10
NADP 9
Ascorbic acid 9
Adrenal 9
CAT 9
more...