Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0242339 (
dyslipidemia
)
13,927
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Meibomian gland dysfunction
(MGD) is the leading cause of dry eye disease and loss of ocular surface homeostasis. Increasingly, several observational clinical studies suggest that
dyslipidemia
(elevated blood cholesterol, triglyceride or lipoprotein levels) can initiate the development of MGD. However, conclusive evidence is lacking, and an experimental approach using a suitable model is necessary to interrogate the relationship between
dyslipidemia
and MGD. This systematic review discusses current knowledge on the associations between
dyslipidemia
and MGD. We briefly introduce a diet-induced obesity model where mice develop
dyslipidemia
, which can serve as a potential tool for investigating the effects of
dyslipidemia
on the meibomian gland. Finally, the utility of lipidomics to examine the link between
dyslipidemia
and MGD is considered.
...
PMID:Dyslipidemia and Meibomian Gland Dysfunction: Utility of Lipidomics and Experimental Prospects with a Diet-Induced Obesity Mouse Model. 3131 67
