Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0241981 (loss of balance)
452 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Postural control deficits are associated with increased risk of loss of balance and potential injury. To assess balance deficits and estimate injury risk, there is a need to evaluate postural control during dynamic activities. Analysis during dynamic activities could assess if an individual's ability to control their posture is a fixed condition or if it is dependent on the demands of a task. The purpose of this study was to evaluate changes in postural control during a dynamic lower extremity task using time-to-contact (TtC) analysis. 3D motion capture with a force plate was used to evaluate 46 healthy recreational athletes performing an anterior reach with the right foot while standing on their left leg. TtC was calculated for nine valid trials. For each trial, the time from the toe leaving the force plate to the toe touching the floor at the maximum reach distance was divided into five epochs of equal duration. TtC was averaged over each epoch. Differences in TtC were evaluated with an unbalanced mixed effects ANOVA and post hoc Tukey's HSD comparisons. Epoch was a significant main effect (p<0.001), with both Epoch 4 and Epoch 5 having significantly greater TtC from all other epochs (p=0.05). Increasing TtC in later epochs suggests a higher demand for postural control when the task becomes more challenging. As an individual's reaching foot extends further from the body, postural control is adjusted to match the changing demands of the dynamic task.
...
PMID:Time-to-contact demonstrates modulation of postural control during a dynamic lower extremity task. 2352 69

Stereotactic radiosurgery (SRS) is a frequently used non-surgical procedure to treat benign and malignant brain lesions. Few studies have focused on patient perceptions of SRS. The aims of this patient-focused study were to assess patient experiences of SRS, and changes in patient-reported symptoms over 12weeks post-SRS. Using the 6-point Likert Scoring Scale in a diary-format for a less discriminatory evaluation, patients self-reported presence or absence, and severity of physical and psychological symptoms within 24h, 1-week, and 12-weeks post-SRS. Non-parametric repeated measures ANOVA was used to evaluate changes in symptoms. Of the 748 recruited patients, 690 returned the first diary (92%), while 564 patients returned all three diaries for matched responses analysis (82%). Three-quarters of 690 patients reported receiving clear verbal explanations and printed material prior to their procedure, and 99% reported the clinical team were 'very supportive' or gave 'wonderful care'. Fatigue (82%) and headaches (65%) were the most frequently reported symptoms within 24-h post-SRS. Over 12weeks, patients reported significant reductions in headache, nausea, fatigue, anxiety and tension (p<0.001); loss of balance and concentration significantly increased by 12-weeks post-SRS (p<0.001). Some patients attributed symptoms such as fatigue or headaches to the demands of the procedure day. Findings of this study reflect the need to further research patients' physical and psychological symptoms post-SRS, which may differ from the clinicians' perception of the effects of treatment.
...
PMID:A prospective patient-focused evaluation of the tolerance and acceptability of a stereotactic radiosurgery procedure. 2826 2