Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0241981 (
loss of balance
)
452
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Dysbiosis, a
loss of balance
between resident bacterial communities and their host, is associated with multiple diseases, including inflammatory bowel diseases (nonspecific chronic ulcerative colitis and Crohn's disease), and digestive functional disorders. Probiotics, prebiotics, synbiotic organisms and, more recently, pharmabiotics, have been shown to modulate the human microbiota. In this review, we provide an overview of the key concepts relating to probiotics, prebiotics, synbiotic organisms, and pharmabiotics, with a focus on available clinical evidence regarding the specific use of a unique pharmabiotic, the strain
Lactobacillus acidophilus
LB (
Lactobacillus boucardii
), for the management of gastrointestinal disorders. Since it does not contain living organisms, the administration of
L. acidophilus
LB is effective and safe as an adjuvant in the treatment of
acute diarrhea
, chronic diarrhea, and antibiotic-associated diarrhea, even in the presence of immunosuppression.
...
PMID:
Lactobacillus acidophilus
LB: a useful pharmabiotic for the treatment of digestive disorders. 3328 37
