Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0240066 (iron deficiency)
7,156 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ferritin 1921
hemoglobin 1431
transferrin 985
erythropoietin 553
transferrin receptor 456
Sep 384
B12 186
C-reactive protein 154
erythroid 153
Mol 150
Hepcidin 139
Ferritin 112
chronic renal failure 102
Erythropoietin 94
hemochromatosis 91
HFE 80
gut 73
melanin-concentrating hormone 70
hereditary hemochromatosis 59
reductase 58
cytokine 58
TfR 54
albumin 51
divalent metal transporter 1 50
ceruloplasmin 49
glycoprotein 47
Transferrin 46
IDA 45
insulin 42
EPO 41
DMT1 39
IRT1 39
superoxide dismutase 38
haptoglobin 38
ATP 37
interleukin-6 36
Pseudomonas 34
IL-6 34
PCC 33
serum albumin 32
catalase 32
CRP 31
hemojuvelin 31
ferroxidase 31
ATPase 28
matriptase-2 27
TMPRSS6 27
FER 26
myoglobin 25
Pol 25
collagen 24
hephaestin 24
aconitase 24
parathyroid hormone 23
basic helix-loop-helix 23
MRI 23
metallothionein 22
thyroid hormone 21
Bot 21
She 19
lactoferrin 19
ferroportin 1 19
proton pump 19
IgA 19
ferredoxin 18
heme oxygenase-1 18
ferrochelatase 18
CD4 18
GSH 18
cytochrome 18
serine protease 17
tumor necrosis factor 17
Chlamydomonas 16
FGF23 16
HAMP 16
alkaline phosphatase 16
ANOVA 16
glucose-6-phosphate dehydrogenase 16
CA1 16
TNF 15
more...
Disease
iron deficiency 7156
anemia 2862
iron deficiency anemia 1074
iron overload 419
thalassemia 297
cancer 271
malnutrition 268
malaria 199
heart failure 187
anemia of chronic disease 176
restless legs syndrome 158
microcytic anemia 129
chronic renal failure 129
hemochromatosis 128
diabetes 124
renal disease 119
hypertension 109
obesity 105
folate deficiency 97
malabsorption 93
hemoglobinopathies 91
inflammatory bowel disease 88
chronic disease 87
chlorosis 83
nutritional disorder 79
sickle cell disease 78
renal failure 77
celiac disease 75
rheumatoid arthritis 73
infectious diseases 69
hereditary hemochromatosis 68
thrombocytosis 66
tumor 65
vitamin B12 deficiency 62
thalassemia trait 55
cardiovascular disease 55
megaloblastic anemia 54
vitamin A deficiency 50
hookworm 50
hypochromic anemia 50
depression 49
uremia 45
thrombocytopenia 45
myelodysplastic syndrome 45
HIV 44
hemolytic anemia 42
gastritis 41
DMT1 39
hyperparathyroidism 38
Parkinson's disease 37
anaemia in pregnancy 36
pheochromocytoma 34
pernicious anemia 34
liver disease 34
pica 34
PCC 33
renal insufficiency 33
West 33
stroke 33
Alzheimer's disease 32
erythrocytosis 31
tuberculosis 29
sepsis 29
heart disease 28
thalassemia minor 28
osteoporosis 27
sepsis 27
rickets 27
cognitive impairment 26
carcinogenesis 25
polycythemia 24
polycythemia vera 23
beta thalassemia 23
prematurity 23
hypothyroidism 23
wasting 23
congestive heart failure 23
Crohn's disease 22
immunodeficiency 22
Helicobacter pylori infection 22
more...
Symptom
fatigue 112
diarrhea 60
starvation 54
overweight 37
splenomegaly 33
headache 29
pain 28
abdominal pain 27
anorexia 24
pallor 21
vomiting 20
discomfort 20
discomfort 20
weakness 18
seizures 16
insomnia 15
anesthesia 15
lethargy 13
constipation 12
nausea 12
exhaustion 12
dyspnea 12
dizziness 11
agitation 10
hunger 9
koilonychia 8
sleepiness 8
paresthesia 7
ataxia 7
asthenia 7
abdominal discomfort 7
hypoproteinemia 6
hepatosplenomegaly 6
hemoptysis 6
tremor 6
acidity 6
Ill 6
arthralgia 5
myalgia 5
heartburn 5
shortness of breath 5
decreased appetite 5
apathy 4
angina 4
epigastric pain 4
dysesthesia 4
colic 3
collapse 3
bradykinesia 3
thinning 3
intestinal bleeding 3
excessive sweating 2
giddiness 2
giddiness 2
bone pain 2
breath holding 2
hepatomegaly 2
nausea and vomiting 2
back pain 2
respiratory distress 2
Fluctuation 2
tingling 2
acute pain 2
numbness 2
wheezing 2
cachexia 2
ENT 2
cough 2
glossodynia 2
cyanosis 2
hypertonia 2
orthopnea 2
chest pain 2
exertional dyspnea 1
Grimace 1
Generalized pruritus 1
chorea 1
body pain 1
Gastrointestinal symptoms 1
No adverse effect 1
more...
Drug
ascorbate 101
Dial 59
Heme 27
Nephron 21
Nephron 19
Kenyan 18
vitamin E 15
Vitamin A 14
Dermatol 13
ROC 12
Vitamin B12 12
ROS 11
NADH 11
Cardiovasc 11
Leaf 11
niacin 10
Epoetin 9
Ferumoxytol 9
Imferon 9
Epoetin alfa 9
CSF 8
lysine 8
Venofer 8
Vitamin B 7
ALA 7
Ferrous sulfate 7
ABC 7
Bayer 6
Albumin 6
FeCl3 6
lactose 5
G-CSF 5
Ferrum 5
PTH 5
Epoetin alfa 5
ENT 4
Orion 4
MDS 4
Spectrum 4
Riboflavin 4
Asn 4
citric acid 4
Darbepoetin alfa 3
Iron dextran 3
AZT 3
Vitamin E 3
Phosphatidylserine 3
Ferrlecit 3
Aprepitant 3
IFN-gamma 3
AZT 3
Monit 3
Serum albumin 3
Dakar 3
IL-2 3
Diurnal 3
Epoetin beta 2
Sinemet 2
Capsicum 2
ETS 2
Folic Acid 2
MAP 2
Omeprazole 2
caffeine 2
p75 2
Sodium nitroprusside 2
Ethanol 2
Ergosterol 2
Tacrolimus 2
FAD 2
Colombo 2
Deferasirox 2
Desferal 2
Carbidopa 2
Desferal 2
Biopolymers 2
PFA 2
Adenosine triphosphate 1
Resovist 1
pyridoxal phosphate 1
more...
Enzyme
ceruloplasmin 64
superoxide dismutase 45
catalase 39
focal adhesion kinase 35
ATPase 31
ferric chelate reductase 28
aconitase 24
ERK 24
peroxidase 23
succinate dehydrogenase 21
glucose-6-phosphate dehydrogenase 19
ferrochelatase 18
proteasome 17
alkaline phosphatase 17
cytochrome oxidase 16
glutathione peroxidase 14
transglutaminase 13
nicotianamine synthase 13
alanine aminotransferase 12
heme oxygenase 12
lactate dehydrogenase 11
monoamine oxidase 11
protein kinase 11
phosphoenolpyruvate carboxykinase 10
phosphoenolpyruvate carboxykinase 10
phosphoenolpyruvate carboxylase 10
DMT 10
phosphoenolpyruvate carboxykinase 10
prolyl hydroxylase 10
aspartate aminotransferase 9
tyrosine hydroxylase 9
ACE 9
thyroid peroxidase 9
diaphorase 8
citrate synthase 8
complex I 8
mitogen-activated protein kinase 8
renin 8
delta-aminolevulinic acid dehydratase 7
ALA synthase 7
caspase-3 6
ribonucleotide reductase 6
isocitrate dehydrogenase 6
thrombin 6
ascorbate peroxidase 6
glutathione reductase 6
lysozyme 6
AMP-activated protein kinase 6
luciferase 6
succinic dehydrogenase 6
protein kinase C 5
ribonucleotide reductase 5
RNA polymerase 5
lactase 5
glutamate dehydrogenase 5
reverse transcriptase 5
beta-glucuronidase 5
glutamate dehydrogenase 5
ACS 5
isocitrate dehydrogenase 5
glutamate dehydrogenase 5
phytase 5
phytase 5
NADPH oxidase 4
sucrase 4
PKG 4
xanthine oxidase 4
NADPH oxidase 4
NQO1 4
glycerol-3-phosphate dehydrogenase 4
CPR 4
gamma-glutamyl transpeptidase 4
glycerol-3-phosphate dehydrogenase 4
acid phosphatase 4
CD10 4
DAT 4
fumarase 4
IDS3 4
invertase 4
NADH dehydrogenase 3
more...
Compound
iron 5624
Clin 718
Dec 466
zinc 351
oxygen 307
Hemoglobin 172
DNA 170
copper 166
calcium 144
sulfate 144
water 126
glucose 80
manganese 76
iodine 76
phosphate 72
salt 71
MCH 70
sodium 68
retinol 62
creatinine 60
cadmium 59
Dial 59
nitrogen 52
vitamin D 52
nitric oxide 50
Cardiol 47
IDA 45
aluminum 41
phosphorus 39
selenium 38
ATP 37
hydrogen 35
EDTA 34
EDTA 34
Heme 31
potassium 29
urea 26
Parenteral 26
acetate 25
Lead 23
ammonium 23
Pac 22
Ascorbic acid 22
PGA 21
CO2 19
His 19
GSH 18
GSH 18
methionine 17
glutamate 17
tyrosine 17
cobalt 17
cysteine 16
ethanol 16
TNF 15
GABA 14
Vitamin A 14
SDS 14
Gly 14
nickel 13
nicotinamide 13
lysine 13
Vitamin D 13
GABA 13
chromium 13
alanine 13
Ferrous sulfate 12
6-12 12
DFO 12
arginine 12
proline 11
NADH 11
NADP 11
homocysteine 11
Dopamine 11
H2O2 11
DMT 10
DMT 10
Zinc protoporphyrin 10
Asp 10
more...