Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0240066 (
iron deficiency
)
7,156
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ferritin
1921
hemoglobin
1431
transferrin
985
erythropoietin
553
transferrin receptor
456
Sep
384
B12
186
C-reactive protein
154
erythroid
153
Mol
150
Hepcidin
139
Ferritin
112
chronic renal failure
102
Erythropoietin
94
hemochromatosis
91
HFE
80
gut
73
melanin-concentrating hormone
70
hereditary hemochromatosis
59
reductase
58
cytokine
58
TfR
54
albumin
51
divalent metal transporter 1
50
ceruloplasmin
49
glycoprotein
47
Transferrin
46
IDA
45
insulin
42
EPO
41
DMT1
39
IRT1
39
superoxide dismutase
38
haptoglobin
38
ATP
37
interleukin-6
36
Pseudomonas
34
IL-6
34
PCC
33
serum albumin
32
catalase
32
CRP
31
hemojuvelin
31
ferroxidase
31
ATPase
28
matriptase-2
27
TMPRSS6
27
FER
26
myoglobin
25
Pol
25
collagen
24
hephaestin
24
aconitase
24
parathyroid hormone
23
basic helix-loop-helix
23
MRI
23
metallothionein
22
thyroid hormone
21
Bot
21
She
19
lactoferrin
19
ferroportin 1
19
proton pump
19
IgA
19
ferredoxin
18
heme oxygenase-1
18
ferrochelatase
18
CD4
18
GSH
18
cytochrome
18
serine protease
17
tumor necrosis factor
17
Chlamydomonas
16
FGF23
16
HAMP
16
alkaline phosphatase
16
ANOVA
16
glucose-6-phosphate dehydrogenase
16
CA1
16
TNF
15
more...
Disease
iron deficiency
7156
anemia
2862
iron deficiency anemia
1074
iron overload
419
thalassemia
297
cancer
271
malnutrition
268
malaria
199
heart failure
187
anemia of chronic disease
176
restless legs syndrome
158
microcytic anemia
129
chronic renal failure
129
hemochromatosis
128
diabetes
124
renal disease
119
hypertension
109
obesity
105
folate deficiency
97
malabsorption
93
hemoglobinopathies
91
inflammatory bowel disease
88
chronic disease
87
chlorosis
83
nutritional disorder
79
sickle cell disease
78
renal failure
77
celiac disease
75
rheumatoid arthritis
73
infectious diseases
69
hereditary hemochromatosis
68
thrombocytosis
66
tumor
65
vitamin B12 deficiency
62
thalassemia trait
55
cardiovascular disease
55
megaloblastic anemia
54
vitamin A deficiency
50
hookworm
50
hypochromic anemia
50
depression
49
uremia
45
thrombocytopenia
45
myelodysplastic syndrome
45
HIV
44
hemolytic anemia
42
gastritis
41
DMT1
39
hyperparathyroidism
38
Parkinson's disease
37
anaemia in pregnancy
36
pheochromocytoma
34
pernicious anemia
34
liver disease
34
pica
34
PCC
33
renal insufficiency
33
West
33
stroke
33
Alzheimer's disease
32
erythrocytosis
31
tuberculosis
29
sepsis
29
heart disease
28
thalassemia minor
28
osteoporosis
27
sepsis
27
rickets
27
cognitive impairment
26
carcinogenesis
25
polycythemia
24
polycythemia vera
23
beta thalassemia
23
prematurity
23
hypothyroidism
23
wasting
23
congestive heart failure
23
Crohn's disease
22
immunodeficiency
22
Helicobacter pylori infection
22
more...
Symptom
fatigue
112
diarrhea
60
starvation
54
overweight
37
splenomegaly
33
headache
29
pain
28
abdominal pain
27
anorexia
24
pallor
21
vomiting
20
discomfort
20
discomfort
20
weakness
18
seizures
16
insomnia
15
anesthesia
15
lethargy
13
constipation
12
nausea
12
exhaustion
12
dyspnea
12
dizziness
11
agitation
10
hunger
9
koilonychia
8
sleepiness
8
paresthesia
7
ataxia
7
asthenia
7
abdominal discomfort
7
hypoproteinemia
6
hepatosplenomegaly
6
hemoptysis
6
tremor
6
acidity
6
Ill
6
arthralgia
5
myalgia
5
heartburn
5
shortness of breath
5
decreased appetite
5
apathy
4
angina
4
epigastric pain
4
dysesthesia
4
colic
3
collapse
3
bradykinesia
3
thinning
3
intestinal bleeding
3
excessive sweating
2
giddiness
2
giddiness
2
bone pain
2
breath holding
2
hepatomegaly
2
nausea and vomiting
2
back pain
2
respiratory distress
2
Fluctuation
2
tingling
2
acute pain
2
numbness
2
wheezing
2
cachexia
2
ENT
2
cough
2
glossodynia
2
cyanosis
2
hypertonia
2
orthopnea
2
chest pain
2
exertional dyspnea
1
Grimace
1
Generalized pruritus
1
chorea
1
body pain
1
Gastrointestinal symptoms
1
No adverse effect
1
more...
Drug
ascorbate
101
Dial
59
Heme
27
Nephron
21
Nephron
19
Kenyan
18
vitamin E
15
Vitamin A
14
Dermatol
13
ROC
12
Vitamin B12
12
ROS
11
NADH
11
Cardiovasc
11
Leaf
11
niacin
10
Epoetin
9
Ferumoxytol
9
Imferon
9
Epoetin alfa
9
CSF
8
lysine
8
Venofer
8
Vitamin B
7
ALA
7
Ferrous sulfate
7
ABC
7
Bayer
6
Albumin
6
FeCl3
6
lactose
5
G-CSF
5
Ferrum
5
PTH
5
Epoetin alfa
5
ENT
4
Orion
4
MDS
4
Spectrum
4
Riboflavin
4
Asn
4
citric acid
4
Darbepoetin alfa
3
Iron dextran
3
AZT
3
Vitamin E
3
Phosphatidylserine
3
Ferrlecit
3
Aprepitant
3
IFN-gamma
3
AZT
3
Monit
3
Serum albumin
3
Dakar
3
IL-2
3
Diurnal
3
Epoetin beta
2
Sinemet
2
Capsicum
2
ETS
2
Folic Acid
2
MAP
2
Omeprazole
2
caffeine
2
p75
2
Sodium nitroprusside
2
Ethanol
2
Ergosterol
2
Tacrolimus
2
FAD
2
Colombo
2
Deferasirox
2
Desferal
2
Carbidopa
2
Desferal
2
Biopolymers
2
PFA
2
Adenosine triphosphate
1
Resovist
1
pyridoxal phosphate
1
more...
Enzyme
ceruloplasmin
64
superoxide dismutase
45
catalase
39
focal adhesion kinase
35
ATPase
31
ferric chelate reductase
28
aconitase
24
ERK
24
peroxidase
23
succinate dehydrogenase
21
glucose-6-phosphate dehydrogenase
19
ferrochelatase
18
proteasome
17
alkaline phosphatase
17
cytochrome oxidase
16
glutathione peroxidase
14
transglutaminase
13
nicotianamine synthase
13
alanine aminotransferase
12
heme oxygenase
12
lactate dehydrogenase
11
monoamine oxidase
11
protein kinase
11
phosphoenolpyruvate carboxykinase
10
phosphoenolpyruvate carboxykinase
10
phosphoenolpyruvate carboxylase
10
DMT
10
phosphoenolpyruvate carboxykinase
10
prolyl hydroxylase
10
aspartate aminotransferase
9
tyrosine hydroxylase
9
ACE
9
thyroid peroxidase
9
diaphorase
8
citrate synthase
8
complex I
8
mitogen-activated protein kinase
8
renin
8
delta-aminolevulinic acid dehydratase
7
ALA synthase
7
caspase-3
6
ribonucleotide reductase
6
isocitrate dehydrogenase
6
thrombin
6
ascorbate peroxidase
6
glutathione reductase
6
lysozyme
6
AMP-activated protein kinase
6
luciferase
6
succinic dehydrogenase
6
protein kinase C
5
ribonucleotide reductase
5
RNA polymerase
5
lactase
5
glutamate dehydrogenase
5
reverse transcriptase
5
beta-glucuronidase
5
glutamate dehydrogenase
5
ACS
5
isocitrate dehydrogenase
5
glutamate dehydrogenase
5
phytase
5
phytase
5
NADPH oxidase
4
sucrase
4
PKG
4
xanthine oxidase
4
NADPH oxidase
4
NQO1
4
glycerol-3-phosphate dehydrogenase
4
CPR
4
gamma-glutamyl transpeptidase
4
glycerol-3-phosphate dehydrogenase
4
acid phosphatase
4
CD10
4
DAT
4
fumarase
4
IDS3
4
invertase
4
NADH dehydrogenase
3
more...
Compound
iron
5624
Clin
718
Dec
466
zinc
351
oxygen
307
Hemoglobin
172
DNA
170
copper
166
calcium
144
sulfate
144
water
126
glucose
80
manganese
76
iodine
76
phosphate
72
salt
71
MCH
70
sodium
68
retinol
62
creatinine
60
cadmium
59
Dial
59
nitrogen
52
vitamin D
52
nitric oxide
50
Cardiol
47
IDA
45
aluminum
41
phosphorus
39
selenium
38
ATP
37
hydrogen
35
EDTA
34
EDTA
34
Heme
31
potassium
29
urea
26
Parenteral
26
acetate
25
Lead
23
ammonium
23
Pac
22
Ascorbic acid
22
PGA
21
CO2
19
His
19
GSH
18
GSH
18
methionine
17
glutamate
17
tyrosine
17
cobalt
17
cysteine
16
ethanol
16
TNF
15
GABA
14
Vitamin A
14
SDS
14
Gly
14
nickel
13
nicotinamide
13
lysine
13
Vitamin D
13
GABA
13
chromium
13
alanine
13
Ferrous sulfate
12
6-12
12
DFO
12
arginine
12
proline
11
NADH
11
NADP
11
homocysteine
11
Dopamine
11
H2O2
11
DMT
10
DMT
10
Zinc protoporphyrin
10
Asp
10
more...