Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0240066 (iron deficiency)
 7,156 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ferritin 1921
hemoglobin 1431
transferrin 985
erythropoietin 553
transferrin receptor 456
Sep 384
B12 186
C-reactive protein 154
erythroid 153
Mol 150
Hepcidin 139
Ferritin 112
chronic renal failure 102
Erythropoietin 94
hemochromatosis 91
HFE 80
gut 73
melanin-concentrating hormone 70
hereditary hemochromatosis 59
cytokine 58
reductase 58
TfR 54
albumin 51
divalent metal transporter 1 50
ceruloplasmin 49
glycoprotein 47
Transferrin 46
IDA 45
insulin 42
EPO 41
DMT1 39
IRT1 39
superoxide dismutase 38
haptoglobin 38
ATP 37
interleukin-6 36
Pseudomonas 34
IL-6 34
PCC 33
catalase 32
serum albumin 32
hemojuvelin 31
ferroxidase 31
CRP 31
ATPase 28
TMPRSS6 27
matriptase-2 27
FER 26
myoglobin 25
Pol 25
collagen 24
hephaestin 24
aconitase 24
parathyroid hormone 23
basic helix-loop-helix 23
MRI 23
metallothionein 22
Bot 21
thyroid hormone 21
IgA 19
lactoferrin 19
ferroportin 1 19
proton pump 19
She 19
heme oxygenase-1 18
ferrochelatase 18
cytochrome 18
ferredoxin 18
GSH 18
CD4 18
serine protease 17
tumor necrosis factor 17
CA1 16
HAMP 16
ANOVA 16
FGF23 16
glucose-6-phosphate dehydrogenase 16
Chlamydomonas 16
alkaline phosphatase 16
TNF 15
endoplasmic reticulum 15
reserved 15
ferroportin1 15
cytochrome c 15
transferrin receptor 2 15
lipopolysaccharide 14
proteasome 14
membrane protein 14
brush border 14
glutathione peroxidase 14
IRP1 13
SDS 13
transcobalamin II 13
GABA 13
histone 13
IRP2 13
IRP 13
lymphoid 12
LPS 12
methemoglobin 12
peroxidase 12
natriuretic peptide 12
intrinsic factor 12
B-12 12
kit 12
polypeptide 11
ROS 11
SOD 11
NADH 11
lactate dehydrogenase 11
thymus 11
tissue transglutaminase 11
FPN1 11
frataxin 11
IL-10 11
bone morphogenetic protein 11
olfactory 11
erythropoietin receptor 10
DMT 10
membrane-bound 10
myeloperoxidase 10
casein 10
RET 10
granulocyte 10
cytochrome P450 10
IFN 10
Cad 9
phosphoenolpyruvate carboxylase 9
p53 9
fur 9
IgE 9
angiotensin receptor 9
ubiquitin 9
tyrosine hydroxylase 9
iron regulatory protein 2 9
B19 9
Gen 9
interferon 9
myelin basic protein 9
GFR 9
HLA 9
P15 9
interleukin 6 8
CD8 8
NMR 8
iron regulatory protein 1 8
caspase-3 8
mitochondrial aconitase 8
white cell 8
nitric oxide synthase 8
functional) 8
duodenal cytochrome b 8
brain-derived neurotrophic factor 8
fibrinogen 8
renin 8
citrate synthase 8
cage 8
dopamine D2 receptor 8
dopamine transporter 8
P65 8
more...
Disease
iron deficiency 7156
anemia 2862
iron deficiency anemia 1074
iron overload 419
thalassemia 297
cancer 271
malnutrition 268
malaria 199
heart failure 187
anemia of chronic disease 176
restless legs syndrome 158
microcytic anemia 129
chronic renal failure 129
hemochromatosis 128
diabetes 124
renal disease 119
hypertension 109
obesity 105
folate deficiency 97
malabsorption 93
hemoglobinopathies 91
inflammatory bowel disease 88
chronic disease 87
chlorosis 83
nutritional disorder 79
sickle cell disease 78
renal failure 77
celiac disease 75
rheumatoid arthritis 73
infectious diseases 69
hereditary hemochromatosis 68
thrombocytosis 66
tumor 65
vitamin B12 deficiency 62
thalassemia trait 55
cardiovascular disease 55
megaloblastic anemia 54
hypochromic anemia 50
vitamin A deficiency 50
hookworm 50
depression 49
thrombocytopenia 45
uremia 45
myelodysplastic syndrome 45
HIV 44
hemolytic anemia 42
gastritis 41
DMT1 39
hyperparathyroidism 38
Parkinson's disease 37
anaemia in pregnancy 36
pheochromocytoma 34
liver disease 34
pica 34
pernicious anemia 34
West 33
PCC 33
renal insufficiency 33
stroke 33
Alzheimer's disease 32
erythrocytosis 31
sepsis 29
tuberculosis 29
thalassemia minor 28
heart disease 28
sepsis 27
rickets 27
osteoporosis 27
cognitive impairment 26
carcinogenesis 25
polycythemia 24
hypothyroidism 23
wasting 23
prematurity 23
beta thalassemia 23
congestive heart failure 23
polycythemia vera 23
immunodeficiency 22
Helicobacter pylori infection 22
Crohn's disease 22
atherosclerosis 21
cold 21
disorders of iron metabolism 21
pulmonary hypertension 21
Best 20
cirrhosis 20
dysphagia 20
SEM 20
lymphoma 20
Infection 20
neuropathy 19
vitamin D deficiency 19
Plummer-Vinson syndrome 19
sleep disorders 19
leukemia 19
neutropenia 19
hepatocellular carcinoma 18
macrocytic anemia 18
aplastic anemia 18
colorectal cancer 18
hypovitaminosis 18
GSH 18
G6PD deficiency 18
infestation 18
coronary artery disease 17
enteropathy 17
pruritus 17
sideroblastic anemia 17
myocardial infarction 16
myeloproliferative disorders 16
intestinal parasites 16
cystic fibrosis 16
type 2 diabetes 15
multiple myeloma 15
leukopenia 15
goiter 15
AIDS 15
anaphylaxis 14
erythropoietic protoporphyria 14
preeclampsia 14
ulcerative colitis 14
sleep disturbances 14
carcinoma 14
worms 14
movement disorder 14
Menkes 14
adenocarcinoma 14
Zinc deficiency 14
pneumonia 14
Mycobacterium 14
breast cancer 13
multiple sclerosis 13
gastric cancer 13
atrophic gastritis 13
siderosis 13
essential thrombocythemia 13
acute myeloid leukemia 13
SDS 13
schizophrenia 12
metabolic syndrome 12
hereditary spherocytosis 12
developmental delay 12
hyperlipidemia 12
mental retardation 12
osteomalacia 12
chronic renal insufficiency 11
Friedreich's ataxia 11
Wilson's disease 11
Iron deficiency without anemia 11
autism 11
myelofibrosis 11
pancytopenia 11
failure to thrive 11
refractory anemia 11
ventricular hypertrophy 11
mental retardation 11
polyneuropathy 11
dyspepsia 11
hyperglycemia 11
colitis 11
more...
Symptom
fatigue 112
diarrhea 60
starvation 54
overweight 37
splenomegaly 33
headache 29
pain 28
abdominal pain 27
anorexia 24
pallor 21
discomfort 20
vomiting 20
discomfort 20
weakness 18
seizures 16
anesthesia 15
insomnia 15
lethargy 13
constipation 12
dyspnea 12
exhaustion 12
nausea 12
dizziness 11
agitation 10
hunger 9
koilonychia 8
sleepiness 8
ataxia 7
asthenia 7
paresthesia 7
abdominal discomfort 7
hemoptysis 6
tremor 6
acidity 6
Ill 6
hepatosplenomegaly 6
hypoproteinemia 6
arthralgia 5
heartburn 5
myalgia 5
shortness of breath 5
decreased appetite 5
apathy 4
epigastric pain 4
angina 4
dysesthesia 4
colic 3
intestinal bleeding 3
bradykinesia 3
thinning 3
collapse 3
excessive sweating 2
giddiness 2
giddiness 2
cough 2
cyanosis 2
Fluctuation 2
nausea and vomiting 2
back pain 2
respiratory distress 2
tingling 2
acute pain 2
glossodynia 2
numbness 2
wheezing 2
hepatomegaly 2
cachexia 2
breath holding 2
ENT 2
bone pain 2
orthopnea 2
hypertonia 2
chest pain 2
low back pain 1
exertional dyspnea 1
Grimace 1
Generalized pruritus 1
chorea 1
body pain 1
Gastrointestinal symptoms 1
No adverse effect 1
physical appearance 1
pelvic pain 1
syncope 1
Depressive symptoms 1
tense 1
nasal discharge 1
regurgitation 1
tonic-clonic seizure 1
tinnitus 1
Cold intolerance 1
lassitude 1
polyuria 1
clubbing 1
abnormal taste 1
acute abdominal pain 1
dystonia 1
hypotonia 1
hyperoxia 1
menometrorrhagia 1
male puberty 1
blurred vision 1
vertigo 1
abnormal gait 1
rales 1
masculinization 1
phosphatemia 1
fever of unknown origin 1
Postoperative nausea and vomiting 1
analgesia 1
flushing 1
Reticulocytosis 1
lightheadedness 1
clumsiness 1
skin damage 1
hip pain 1
unable to sleep 1
Central cyanosis 1
twitching 1
chills 1
hypercapnia 1
cerebellar ataxia 1
hypothermia 1
snoring 1
paraparesis 1
forgetfulness 1
thirsty 1
myoclonus 1
growing pains 1
general problem 1
dry skin 1
leg pain 1
Drug
ascorbate 101
Dial 59
Heme 27
Nephron 21
Nephron 19
Kenyan 18
vitamin E 15
Vitamin A 14
Dermatol 13
ROC 12
Vitamin B12 12
ROS 11
NADH 11
Cardiovasc 11
Leaf 11
niacin 10
Epoetin 9
Epoetin alfa 9
Imferon 9
Ferumoxytol 9
Venofer 8
CSF 8
lysine 8
Vitamin B 7
Ferrous sulfate 7
ABC 7
ALA 7
FeCl3 6
Albumin 6
Bayer 6
G-CSF 5
lactose 5
Epoetin alfa 5
Ferrum 5
PTH 5
ENT 4
MDS 4
Riboflavin 4
Spectrum 4
Asn 4
Orion 4
citric acid 4
Darbepoetin alfa 3
Iron dextran 3
AZT 3
Dakar 3
Monit 3
Ferrlecit 3
AZT 3
IFN-gamma 3
Aprepitant 3
Serum albumin 3
Phosphatidylserine 3
Vitamin E 3
Diurnal 3
IL-2 3
Omeprazole 2
Capsicum 2
MAP 2
Sodium nitroprusside 2
Ethanol 2
Ergosterol 2
Biopolymers 2
Tacrolimus 2
FAD 2
Colombo 2
Deferasirox 2
Desferal 2
Carbidopa 2
Desferal 2
Epoetin beta 2
Folic Acid 2
ETS 2
p75 2
Sinemet 2
PFA 2
caffeine 2
Adenosine triphosphate 1
nitroglycerin 1
Resovist 1
CoCl2 1
CoCl2 1
MRC 1
CTC 1
EHDP 1
Gabapentin 1
Parkin 1
Phenytoin 1
CDP 1
Eculizumab 1
balanced salt solution 1
EPI 1
L-Ser 1
Fusicoccin 1
THF 1
Carotenoid 1
Cobalamin 1
SMP 1
CrCl3 1
Polaprezinc 1
Trib 1
PCP 1
Ferumoxtran-10 1
Vitamin K 1
Camphor 1
DNase I 1
Bifidobacterium 1
Gastro 1
Gel 1
Infliximab 1
Triclosan 1
THA 1
ZnO 1
Infliximab 1
EE2 1
Parkin 1
Gelatin 1
IL-11 1
Calamine 1
Estrogens 1
Alliance 1
PCB 1
Check 1
CTC 1
Glutathione 1
Rotigotine 1
Dextrose 1
Ferumoxides 1
ACT 1
pyridoxal phosphate 1
DEL 1
Lactose 1
9-THC 1
Prednisolone 1
Camphor 1
ICI 1
CVA 1
Flavin 1
Asthma 1
Coral 1
Enzyme
ceruloplasmin 64
superoxide dismutase 45
catalase 39
focal adhesion kinase 35
ATPase 31
ferric chelate reductase 28
ERK 24
aconitase 24
peroxidase 23
succinate dehydrogenase 21
glucose-6-phosphate dehydrogenase 19
ferrochelatase 18
alkaline phosphatase 17
proteasome 17
cytochrome oxidase 16
glutathione peroxidase 14
transglutaminase 13
nicotianamine synthase 13
heme oxygenase 12
alanine aminotransferase 12
monoamine oxidase 11
protein kinase 11
lactate dehydrogenase 11
phosphoenolpyruvate carboxykinase 10
prolyl hydroxylase 10
DMT 10
phosphoenolpyruvate carboxykinase 10
phosphoenolpyruvate carboxylase 10
phosphoenolpyruvate carboxykinase 10
aspartate aminotransferase 9
ACE 9
thyroid peroxidase 9
tyrosine hydroxylase 9
renin 8
citrate synthase 8
mitogen-activated protein kinase 8
diaphorase 8
complex I 8
delta-aminolevulinic acid dehydratase 7
ALA synthase 7
ascorbate peroxidase 6
luciferase 6
caspase-3 6
glutathione reductase 6
AMP-activated protein kinase 6
isocitrate dehydrogenase 6
succinic dehydrogenase 6
thrombin 6
lysozyme 6
ribonucleotide reductase 6
lactase 5
protein kinase C 5
ribonucleotide reductase 5
ACS 5
reverse transcriptase 5
phytase 5
isocitrate dehydrogenase 5
phytase 5
RNA polymerase 5
beta-glucuronidase 5
glutamate dehydrogenase 5
glutamate dehydrogenase 5
glutamate dehydrogenase 5
NQO1 4
glycerol-3-phosphate dehydrogenase 4
xanthine oxidase 4
gamma-glutamyl transpeptidase 4
IDS3 4
PKG 4
CD10 4
glycerol-3-phosphate dehydrogenase 4
acid phosphatase 4
DAT 4
fumarase 4
sucrase 4
NADPH oxidase 4
CPR 4
NADPH oxidase 4
invertase 4
diamine oxidase 3
alpha-glucosidase 3
tryptophan 2,3-dioxygenase 3
nitrogenase 3
aldehyde dehydrogenase 3
lipase 3
methionine synthase 3
AMPK 3
thromboplastin 3
IDS2 3
peroxiredoxin 3
methionine synthase 3
coproporphyrinogen oxidase 3
nitrate reductase 3
6-phosphogluconate dehydrogenase 3
CNPase 3
6-phosphogluconate dehydrogenase 3
alcohol dehydrogenase 3
NADH dehydrogenase 3
GTP cyclohydrolase I 3
insulin-degrading enzyme 3
malate dehydrogenase 3
3-hydroxyacyl-CoA dehydrogenase 3
NAAT 3
riboflavin synthase 3
phenylalanine hydroxylase 3
AMPK 3
aldehyde dehydrogenase 2
glycerol-3-phosphate oxidase 2
glutathione S-transferase 2
myosin light chain kinase 2
acetylcholinesterase 2
hexokinase 2
pantothenate kinase 2
DNA polymerase 2
phospholipase A2 2
adrenodoxin reductase 2
ATP synthase 2
deaminase 2
demethylase 2
xanthine dehydrogenase 2
AMP-activated kinase 2
folylpolyglutamate synthetase 2
glutamate decarboxylase 2
APC 2
Thy1 2
furin 2
nitrate reductase 2
nitrate reductase 2
matriptase 2
thioredoxin reductase 2
calcineurin 2
tyrosinase 2
ECH 2
matriptase 2
nitrate reductase 2
nitrate reductase 2
pyruvate carboxylase 2
nitrate reductase 2
NOS 2
fatty acid desaturase 2
pepsin 2
elastase 2
porphobilinogen deaminase 2
NO synthase 2
3-hydroxyacyl-CoA dehydrogenase 2
GAS 2
IscS 2
cholinesterase 2
isochorismate synthase 2
lysyl oxidase 2
neutrophil elastase 1
cathepsin K 1
transcriptase 1
hydrogenase 1
Protein 2 1
glutamate synthase 1
indoleamine 2,3-dioxygenase 1
trypsin 1
PAL 1
MDH 1
more...
Compound
iron 5624
Clin 718
Dec 466
zinc 351
oxygen 307
Hemoglobin 172
DNA 170
copper 166
calcium 144
sulfate 144
water 126
glucose 80
iodine 76
manganese 76
phosphate 72
salt 71
MCH 70
sodium 68
retinol 62
creatinine 60
Dial 59
cadmium 59
nitrogen 52
vitamin D 52
nitric oxide 50
Cardiol 47
IDA 45
aluminum 41
phosphorus 39
selenium 38
ATP 37
hydrogen 35
EDTA 34
EDTA 34
Heme 31
potassium 29
urea 26
Parenteral 26
acetate 25
Lead 23
ammonium 23
Ascorbic acid 22
Pac 22
PGA 21
His 19
CO2 19
GSH 18
GSH 18
methionine 17
cobalt 17
tyrosine 17
glutamate 17
ethanol 16
cysteine 16
TNF 15
Vitamin A 14
SDS 14
GABA 14
Gly 14
GABA 13
nicotinamide 13
chromium 13
Vitamin D 13
lysine 13
nickel 13
alanine 13
arginine 12
6-12 12
Ferrous sulfate 12
DFO 12
NADP 11
proline 11
H2O2 11
Dopamine 11
NADH 11
homocysteine 11
Zinc protoporphyrin 10
DMT 10
Asp 10
hydroxide 10
DMT 10
Hearts 9
delta-aminolevulinic acid 9
2-oxoglutarate 9
nitrate 9
Salt 9
glutamine 9
mercury 9
TSH 8
tryptophan 8
aldosterone 8
NAD 8
tryptophan 8
nicotinic acid 8
MDA 8
Phe 8
tryptophan 8
salicylic acid 8
tryptophan 8
2,3-diphosphoglycerate 8
Thyroid 8
TCA 7
BMC 7
acetic acid 7
Phytol 7
leucine 7
CAT 7
L-DOPA 7
Phytol 7
Yellow 7
Benin 7
carbonate 7
CAT 7
CAT 7
ADP 7
Optimal 7
Mg2+ 7
Hemin 6
CoA 6
Hemin 6
Hemin 6
FMN 6
Hemin 6
serine 6
Hemin 6
gamma-aminobutyric acid 6
NAD 6
5-HT 6
Abbott 5
valine 5
cyanide 5
Protoporphyrin IX 5
L-carnitine 5
aspartic acid 5
ACS 5
ACS 5
Ile 5
Pyruvate 5
DBA 5
noradrenaline 5
phosphocreatine 5
PEG 5
HBB 5
Sucrose 5
DSM 5
asparagine 5
galactose 5
NTA 5
molybdenum 5
N-acetylcysteine 5
TOF 5
barium 5
Insulin 5
DEAE 4
threonine 4
Lactate 4
DHBA 4
DBA 4
aspartic acid 4
NADPH 4
more...