Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0240066 (iron deficiency)
 7,156 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The objective of this investigation was to ascertain the biocompatability of a ferric calcium phosphorous oxide ceramic (FECAP). The FECAP ceramic was fabricated from stock powders combined in a ratio of 46:40:14 by weight of Fe2O3:CaO:P2O5. The composite oxides were mixed for homogeneity, pressed into a 20g block, and calcined in a crucible at 1100 degrees C for 12 hours. The calcined ceramic was then ground in a ball mill before separation into particle sizes of 38-45 microns and 63-75 microns, by an automatic siever and shaker. Calcined powders of each particle size were mixed with polyvinyl alcohol binder (0.025g PVA/1.0g of FECAP), and pressed into 0.5g pellets in a 5/16" (internal diameter) die at a 1820 kilogram load using a Carver hydraulic press. FECAP pellets were then sintered at 1100 degrees C for 12 hours. For this investigation, sixty albino (Sprague-Dawley) rats weighing 125-425 g each, were distributed into four groups: non-operated controls, sham-operated controls, and two groups subcutaneously implanted with ceramics 38-45 microns and 63-75 microns FECAP ceramics, respectively. Three rats from each group were sacrificed at three, five, seven, and twenty-one days post-surgery. Morphologic examination of the implant and implant site as well as hematocrit data indicate that this ferric-calcium-phosphorous oxide ceramic is biocompatible. Data obtained todate suggest that sintered FECAP should have a wide variety of dental and medical applications, especially where iron deficiency is a concern.
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PMID:Biocompatibility of ferric calcium phosphorous oxide ceramics. 164 15

Two citrus rootstocks, one sensitive to iron deficiency (Swingle Citrumelo (SCO)) and the other tolerant (Carrizo Citrange, (CC)), were studied to characterize variation in their root protein profile induced by iron-deficient conditions. Plants of both rootstocks were grown in two different soils, one volcanic (v) and the other calcareous (c), containing 0% and 10% active Lime, respectively. To evaluate the effects of the calcareous soil on the protein accumulation of both rootstocks, the root protein profiles (SCc vs. SCv and CCc vs. CCv) were characterized by two-dimensional gel electrophoresis, thus obtaining, for the first time, a reference map of this previously uncharacterized proteome. A total of 219 spots, significantly changed in abundance, were analyzed by high-performance Liquid chromatography nano electrospray ionization tandem mass spectrometry. The identified proteins were classified according to their putative function and known biosynthetic pathways. Principal component analysis, comparing the four sets of data, indicated that each group clustered together with low variance and that CCv and CCc data sets were well differentiated, whereas SCv and SCc were similar.
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PMID:Root protein profiles of two citrus rootstocks grown under iron sufficiency/deficiency conditions. 2457 29