Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0240066 (
iron deficiency
)
7,156
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Iron deficiency
is the most common nutritional disorder affecting at least one third of world's population. Though anemia is common manifestation of
iron deficiency
, other effects of
iron deficiency
on various tissues, organs and systems are usually under recognized. Impaired brain development and cognitive, behavioural and
psychomotor impairment
are most worrisome manifestations of
iron deficiency
. Studies have demonstrated that some of these changes occurring during period of brain growth spurt (<2 years age) may be irreversible. Association of
iron deficiency
with febrile seizures, pica, breath holding spells, restless leg syndrome and thrombosis is increasingly being recognized. Impaired cell-mediated immunity and bactericidal function are generally noted in iron-deficient persons; however, the findings are inconsistent. Despite proven reversible functional immunological defects in vitro studies, a clinically important relationship between states of
iron deficiency
and susceptibility to infections remains controversial. Studies from malaria endemic regions have reported increased incidence of malaria in association with iron supplementation. These and some other aspects of
iron deficiency
are reviewed in this article.
...
PMID:Iron deficiency: beyond anemia. 2081 42
