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Query: UMLS:C0240066 (iron deficiency)
 7,156 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Oral precancer encompasses several conditions and lesions. Among those entities included in the concept are leukoplakia, erythroplakia, lichen planus, and submucous fibrosis. For prevention, knowledge about etiologic and pathogenetic factors is imperative. It is well-known that excessive consumption of tobacco and alcohol has a bearing on the development of oral leukoplakia and probably also of erythroplakia. However, among leukoplakias, the idiopathic or cryptogenic type probably shows the most serious malignant potential. Involved in the development of such lesions may be general nutritional aspects, e.g., proper utilization of vitamin A. It is also well-known that iron deficiency has been linked to Plummer-Vinson's syndrome, showing a precancerous trait. Among factors involved in the pathogenesis of lichen planus is probably mental stress. Thus, stress factors and related neurological components have been linked to the immunological system. Lifestyle factors, such as nutrition, tobacco, and alcohol, and also mental environment may be of importance for the development of oral precancer and cancer.
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PMID:Early diagnosis and prevention of oral cancer and precancer: report of Symposium III. 754 34

Pica, the purposive consumption of nonfood substances, is a millennia-old nutritional enigma. Its worldwide ubiquity, prevalence among pregnant women and children, and association with both positive and negative health outcomes, especially micronutrient deficiencies, underscore the importance of understanding this behavior. Multiple proposed etiologies of pica are reviewed, including cultural expectations, psychological stress, hunger, dyspepsia, micronutrient deficiencies (Fe, Zn, and Ca), and protection against toxins and pathogens. Currently available data, although limited, best support the protection hypothesis as a cause of most types of pica, although some evidence suggests that pagophagy (ice consumption) may occur during iron deficiency. It is possible that the binding capacity of pica substances explains the association with micronutrient deficiencies; earth, starch, etc. may render micronutrients in ingesta unavailable for absorption. Increased research efforts are warranted and must be hypothesis driven, interdisciplinary, and permit the testing of multiple causal inferences.
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PMID:Pica in pregnancy: new ideas about an old condition. 2042 May 23

The significance of physical activity for fitness is that it may change risk factors for chronic disease and improve functional and psychological status. Rational nutrition and scientific training are prerequisites for safe and useful exercise. Even mild iron deficiency anemia can affect physical capacity. Intensive exercise has been found to increase serum and erythrocyte lipid peroxide levels. Moderate exercise decreases the blood lipid peroxides and increases free radical elimination enzyme (SOD, GSH-Px, CAT) activities. Elite athletes have significantly lower Malonic dialdehyde (MDA) levels and higher SOD and GSH-Px activities. Zinc deficiency not only leads to an increase in free radical generation and lipid peroxidation and a depression of SOD activity, but also is harmful to immune function. Exercise can exacerbate the damage induced by iron deficiency or zinc deficiency. Long term diet restriction by gymnasts to control weight showed detrimental effects including growth retardation, menstrual disturbances, malnutrition, mental stress and muscle weakness. Comprehensive nutrition promotes growth rate and corrects malnutrition without a body fat increase in athletes. Exercise benefits the growth and development of bone and muscle and enhances muscle strength. The prevention of obesity is particularly important during periods of rapid growth. The establishment of an exercise life style during childhood will favor the best health.
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PMID:Benefits of physical activity on nutrition and health status: studies in China. 2439 41