Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0240066 (iron deficiency)
 7,156 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

On the one hand, hemochromatosis is an autosomal recessive disease characterized by a high iron absorption from the gut, and it is the most frequent cause of iron overload. On the other hand, celiac disease is an immunomediated entity caused by exposure to dietary gluten in genetically predisposed individuals. Celiac disease is characterized by the destruction of enterocytes that usually manifest with anemia due to iron deficiency. The concomitant presence of both entities is very rare. We present the case of a 14-year-old adolescent diagnosed with hereditary hemochromatosis due to an alteration of the iron profile in routine laboratory tests. One year later, she began with diarrhea and abdominal discomfort, also confirming the diagnosis of celiac disease. Nowadays, she remains asymptomatic and without phlebotomies, but this could be necessary in the future when the celiac disease is corrected and therefore the associated iron absorption deficit too.
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PMID:Balanced by iron. Hereditary hemochromatosis and celiac disease. 3323 8


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