Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0239946 (liver fibrosis)
 8,268 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
degenerative spermatocyte homolog 1 11.9
TAOK1 protein 11.9
NTPDase 6 11.9
syntaxin binding protein 5-like 11.9
zinc finger protein 267 10.9
XLKD1 10.9
B9D1 protein 10.9
NCU-G1 10.9
G protein-coupled receptor 137B 10.9
Milk fat globule-EGF factor 8 protein 10.3
actin, alpha 2, smooth muscle, aorta 10.3
tetratricopeptide repeat domain 3 9.9
OXSM 9.9
LPPR4 9.9
transmembrane 4 L six family member 5 9.9
OGFRL1 9.9
F-box protein 31 9.9
transmembrane 6 superfamily member 2 9.7
M2BP 9.7
PHKG2 9.6
lysyl oxidase-like 3 9.6
ARMC9 9.6
Noxp20 9.6
FETUB 9.3
extrahepatic UDP-glucuronosyltransferase 9.3
TMEM219 9.3
KRAB A domain 9.3
LPIAT 9.1
TCTN3 9.1
SIDT1 9.1
NOL10 9.1
NOV protein 8.9
PWWP2A 8.9
septin 8 8.9
protein phosphatase 2 regulatory subunit B 8.9
inositol polyphosphate-5-phosphatase E 8.9
alpha1(I) procollagen 8.9
CC2D2A 8.9
LARP6 8.8
MBOAT7 8.8
uridine phosphorylase 1 8.7
TMC4 8.7
Tissue-specific extinguisher 1 8.7
SCRG1 8.7
Angiogenic factor with G patch and FHA domains 1 8.7
CD158i 8.7
PCPE-1 8.7
tissue inhibitor of metalloproteinase 1 8.6
FIB 8.6
QBRICK 8.6
TCTN2 8.6
GSD IX 8.6
MMP1 protein 8.6
IFN-alpha 6 8.6
TCTN1 8.6
C17orf32 8.6
Transgelin-2 8.6
Fibroblast growth factor 7 8.6
CCDC115 8.6
GRB2 protein 8.6
Cytoglobin 8.6
TM4SF5 8.5
TMEM216 8.5
B9D1 8.5
FIH1 8.5
PNPLA3 8.4
PHKB 8.4
microtubule-associated proteins 1A/1B light chain 3 8.3
Secretin receptor 8.3
TM6SF2 8.3
RNF7 8.3
neuronal tryptophan hydroxylase 8.3
TIMP metallopeptidase inhibitor 1 8.3
XPNPEP1 8.3
metalloprotease 1 8.3
HSC 8.2
DNASE2 8.2
G protein-coupled receptor 35 8.2
histidine-rich calcium-binding protein 8.2
RPGRIP1L 8.2
more...
Disease
NPHP1, DEL 11.9
liver fibrosis 11.9
liver scarring 10.8
Hepatic siderosis 10.1
Advanced chronic liver disease 9.9
Hepatic capillariasis 9.9
Infection by Opisthorchis viverrini 9.9
Hepatic schistosomiasis 9.7
Biliary fibrosis 9.7
Bile duct proliferation 9.7
Liver cholestasis 9.6
Sickle cell thalassemia 9.6
Kupffer cell sarcoma 9.6
Hepatic fibrosis and cirrhosis 9.3
Severe chronic obstructive pulmonary disease 9.3
Secondary biliary cirrhosis 9.3
nutmeg liver 9.1
Schistosoma mekongi infection 9.1
Greenberg dysplasia 8.9
GSD IX 8.8
Plasma cell infiltration 8.7
Hepatic glycogenosis 8.7
HCV coinfection 8.5
Radiation-induced liver disease 8.5
Chronic liver disease and cirrhosis 8.5
Congenital hepatic fibrosis 8.3
Hepatic congestion 8.3
PGL4 8.3
Chronic viral hepatitis 8.3
cholangiolitis 8.2
essential thrombocytopenia 8.2
Chronic hepatitis C 8.2
HFE2 8.1
Cirrhosis 8.1
Hepatic osteodystrophy 8.1
End stage liver disease 8.1
PFIC2 8.1
PFIC1 8.1
Nonalcoholic fatty liver 8.0
Secondary sclerosing cholangitis 8.0
NPHP2 8.0
chronic liver disease 7.9
Hepatosplenic schistosomiasis 7.9
NPHP1 7.9
MKS3 7.8
cirrhosis 7.8
alcoholic fatty liver 7.7
Portal vein occlusion 7.7
cholemia 7.7
cholesterol ester storage disease 7.7
PFIC3 7.7
Cholestatic hepatitis 7.6
Cholestatic liver disease 7.5
Choledochal cyst 7.5
cholestatic cirrhosis 7.4
chronic hepatitis 7.4
NPHP3 7.3
Skeletal dysplasia 7.3
Decompensated cirrhosis 7.3
Schistosoma japonicum 7.3
Pelger-Huet 7.2
Autoimmune liver disease 7.2
Hepatocarcinogenesis 7.2
fatty liver 7.1
Alcoholic liver disease 7.1
liver disease 7.1
portal hypertension 7.0
Chronic hepatitis B 7.0
Cryoglobulinemic vasculitis 7.0
viral hepatitis 7.0
Overlap syndrome 7.0
Acute hepatitis E 7.0
biliary atresia 6.9
astereognosis 6.9
Schistosoma mansoni infection 6.8
alcoholic hepatitis 6.8
Catastrophic Illness 6.8
Echinococcus multilocularis infection 6.8
neuroblastoma stage 6.7
Hypervitaminosis A 6.6
more...
Symptom
Balding 6.9
hepatomegaly 5.4
Stiffness 5.1
dark urine 4.8
frequent urination 4.5
splenomegaly 4.4
loss of balance 4.1
HSA 3.8
hepatosplenomegaly 3.6
leg edema 3.5
Spots 3.1
tenesmus 3.0
Anoxia 2.8
right upper quadrant pain 2.5
hypotonia 2.4
general problem 2.2
cerebellar ataxia 2.1
overweight 2.1
emaciation 1.9
ataxia 1.9
polydipsia 1.8
hypoproteinemia 1.8
night sweats 1.7
exhaustion 1.6
pallor 1.6
arthralgia 1.4
skin damage 1.3
polyuria 1.3
enuresis 1.2
abdominal discomfort 1.2
neuralgia 1.1
regurgitation 0.9
skin irritation 0.8
cachexia 0.4
abdominal pain 0.3
fatigue 0.1
dysarthria 0.0
weakness 0.0
apathy -0.1
diarrhea -0.1
starvation -0.1
dystonia -0.1
erythema -0.2
discomfort -0.2
anorexia -0.3
cough -0.3
discomfort -0.3
hyperoxia -0.4
hunger -0.6
lethargy -0.6
flushing -0.7
respiratory distress -0.8
myalgia -0.8
angina -0.9
hypercapnia -1.0
pain -1.2
tremor -1.3
collapse -1.3
vomiting -1.5
Ill -1.5
seizures -1.6
nausea -1.6
agitation -1.6
anesthesia -1.7
sleepiness -1.7
stigma -1.8
functional recovery -1.8
dyspnea -1.9
chest pain -2.2
headache -3.9
Drug
Livact 10.3
Gadoxetate disodium 8.5
Malotilate 8.1
Camellia oil 8.1
Meridia 7.9
Alendronate sodium 7.3
Polaprezinc 7.0
Omacor 6.4
Pirfenidone 6.3
Trapidil 6.1
Midostaurin 5.9
Emodin 5.8
NOV 5.8
Zileuton 5.6
CCL 5.6
Calcipotriol 5.6
Emodin 5.5
Etravirine 5.5
Muse 5.4
Valganciclovir 5.4
Pegasys 5.4
Tenofovir 5.2
Verteporfin 5.2
Tolvaptan 5.2
Sorafenib 5.2
Ulinastatin 5.1
Swertia 5.0
Portal 5.0
Deoxyadenosine 5.0
ATV 4.9
Rhubarb 4.9
Liraglutide 4.7
Vinpocetine 4.7
Ezetimibe 4.7
Corn oil 4.6
Myricetin 4.6
Fenbendazole 4.6
PFT 4.6
Rimonabant 4.6
Beta-2 4.5
3-Methyladenine 4.5
2-Methoxyestradiol 4.5
Artesunate 4.5
PDGF B-chain 4.4
Maraviroc 4.3
Cetrorelix 4.3
PMPA 4.3
Tranilast 4.2
Serum albumin 4.2
Cilostazol 4.2
Olmesartan 4.2
Activin 4.2
ROC 4.2
Epigallocatechin 4.1
Entecavir 4.1
Entecavir 4.1
Mesalazine 4.1
Raltegravir 4.1
Secretin 4.0
Crystal Violet 4.0
Vitamin A 3.9
Clodronate 3.9
Pyridoxal 3.9
Aliskiren 3.9
Angiotensin II 3.8
GNA 3.8
Bezafibrate 3.8
Ketotifen 3.7
Palmitoyl 3.7
Ketorolac 3.7
Sandostatin 3.7
Sandostatin 3.7
Mirtazapine 3.6
Copaxone 3.6
Ergosterol 3.6
Perindopril 3.5
Auranofin 3.5
AC2 3.5
Limonene 3.4
Infliximab 3.4
more...
Enzyme
EC 2.4.2.16 11.9
calpain 9 8.9
type III procollagen 8.2
galactosylhydroxylysyl glucosyltransferase 7.1
AST 7.0
aspartate aminotransferase 6.8
alanine aminotransferase 6.7
interstitial collagenase 6.5
lysophospholipase D 6.1
fumarylacetoacetate hydrolase 6.1
prolyl hydroxylase 6.0
collagenase 3 5.9
cathepsin F 5.9
D-dopachrome tautomerase 5.9
glycerate kinase 5.8
retinal dehydrogenase 5.8
lysyl oxidase 5.8
7-dehydrocholesterol reductase 5.8
inosine triphosphatase 5.6
CYP8B1 5.4
gamma-glutamyl transpeptidase 5.4
retinol acyltransferase 5.4
isovaleryl-CoA dehydrogenase 5.4
dynamin GTPase 5.2
phosphomannose isomerase 5.0
collagenase 4.9
methionine adenosyltransferase 4.8
formyltetrahydrofolate synthetase 4.8
methylenetetrahydrofolate dehydrogenase 4.7
SLB 4.7
dimethylarginine dimethylaminohydrolase 4.6
carbamoylphosphate synthetase 4.6
protein disulfide-isomerase 4.6
lecithin:retinol acyltransferase 4.6
matrix metalloproteinase 2 4.5
prolidase 4.5
phosphorylase kinase 4.4
matrix metalloproteinase 9 4.4
estrogen sulfotransferase 4.4
MMP 4.3
CYP7A1 4.3
AMPK 4.2
argininosuccinate lyase 4.2
endothelin-converting enzyme 4.2
DNase II 4.2
arylalkylamine N-acetyltransferase 4.1
chymase 4.1
PRT 4.1
4-hydroxyphenylpyruvate dioxygenase 4.1
phosphomannomutase 4.0
PPH 4.0
GAR 4.0
sphingosine kinase 3.9
angiotensin-converting enzyme 2 3.9
ADH3 3.9
MMP-3 3.9
CYP27A1 3.8
12-lipoxygenase 3.7
tryptophan 2,3-dioxygenase 3.7
caspase-7 3.7
ALDH 3.7
caspase-7 3.7
AMP-activated protein kinase 3.6
NADPH oxidase 3.6
NADPH oxidase 3.5
alkaline phosphatase 3.5
Omi/HtrA2 3.5
caspase-1 3.5
gamma-glutamylcysteine synthetase 3.4
caspase-3 3.4
caspase-4 3.4
guanylate kinase 3.4
transpeptidase 3.4
PME 3.4
alpha-L-iduronidase 3.4
prostacyclin synthase 3.3
SST 3.3
legumain 3.3
PMT 3.3
AMPK 3.3
more...
Compound
Trimethylhydroquinone 11.9
Tetrachloride 10.5
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C23H28O11 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 10.3
C9H9NO 9.9
C23H28O11 9.9
C9H9NO 9.9
C9H9NO 9.9
C9H9NO 9.9
C9H9NO 9.9
C9H9NO 9.6
3-(4-hydroxyphenyl)propanenitrile 9.6
Isobrucein B 9.6
Wuweizisu C 9.3
C10H15NO 9.3
6-ECDCA 9.1
3-phenylacrylamide 9.1
C10H16O4 8.9
Isochlorogenic acid 8.9
Benalaxyl 8.7
C11H13NO3 8.7
CCl4 8.6
Yangonin 8.3
5-Methoxyindole 8.3
Yangonin 8.1
Cinnamamide 8.1
Phyllanthin 8.1
2-fluorobenzoic acid 8.0
TMCA 7.9
Boswellic acid 7.9
N-phenylacrylamide 7.7
Amarogentin 7.7
NAMS 7.7
TMCA 7.6
Rubratoxin B 7.5
Fraxetin 7.5
cholest-4-ene 7.5
3-heptanol 7.4
Stachydrine 7.4
Sennoside A 7.4
2-octynoic acid 7.3
AEK 7.3
Azan 7.3
2-nonenoic acid 7.2
Glycochenodeoxycholic acid 7.1
Oltipraz 7.1
Gadolinium chloride 7.0
Tectorigenin 6.9
Loganin 6.9
Physcion 6.9
Pyrantel 6.8
Matrine 6.8
Matrine 6.8
Matrine 6.8
1-nonene 6.8
Chrysophanol 6.8
Ditan 6.7
Chrysophanol 6.7
more...