Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0239946 (liver fibrosis)
8,268 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein collagen 1627 Mol 597 SMA 591 Sep 490 smooth muscle actin 480 aspartate aminotransferase 445 alanine aminotransferase 416 cytokine 356 interferon 329 insulin 279 TNF 227 AST 207 albumin 200 tumor necrosis factor 193 alpha-smooth muscle actin 192 matrix metalloproteinase 160 type I collagen 159 FIB 158 Smad3 150 IL-6 149 HSC 149 platelet-derived growth factor 145 fibronectin 144 alkaline phosphatase 141 Smad2 135 caspase-3 131 IFN 129 EPA 125 superoxide dismutase 103 GSH 102 PDGF 100 CD4 94 TGF-beta 92 serum albumin 91 connective tissue growth factor 89 IL-10 86 gut 84 TLR4 83 MMP-2 81 chemokine 77 p38 75 Bcl-2 75 MRI 74 transforming growth factor-beta 74 vascular endothelial growth factor 73 ERK 72 leptin 72 AKT 71 desmin 70 lipopolysaccharide 69 PI3K 68 endoplasmic reticulum 68 metalloproteinase 65 catenin 65 vimentin 63 ferritin 63 MMP-9 62 hepatocyte growth factor 61 inducible nitric oxide synthase 61 peroxisome proliferator-activated receptor 60 interleukin-6 59 MAPK 59 renin 58 ERK1 58 collagenase 57 IL-13 55 JNK 55 adiponectin 54 LPS 50 ECM 50 tissue inhibitor of metalloproteinases 50 catalase 49 STAT3 49 p53 49 glutathione peroxidase 48 Smad7 47 PPAR 46 HCC 46 prothrombin 46 surface antigen 45 more...

Disease liver fibrosis 8268 cirrhosis 2386 liver disease 1138 hepatocellular carcinoma 1026 chronic hepatitis 891 hepatitis C 743 chronic liver disease 565 fatty liver 512 cancer 375 hepatitis B 353 portal hypertension 316 hepatitis 294 obesity 268 viral hepatitis 259 tumor 244 diabetes 238 Nonalcoholic fatty liver 232 liver cancer 228 cholestasis 211 schistosomiasis 209 alcoholic fatty liver 201 HIV 181 liver cancer 181 metabolic syndrome 163 virus infection 150 type 2 diabetes 116 GSH 102 immunodeficiency 101 carcinogenesis 99 Schistosoma mansoni 96 iron overload 90 Schistosoma japonicum 87 Cirrhosis 81 hypertension 78 biliary atresia 70 primary biliary cirrhosis 70 alcohol abuse 68 Chronic hepatitis C 68 tumorigenesis 65 Hepatocellular carcinoma 62 cholangitis 61 atherosclerosis 58 esophageal varices 57 cardiovascular disease 52 primary sclerosing cholangitis 46 HCC 46 acute hepatitis 45 AIDS 45 pulmonary fibrosis 44 hemochromatosis 43 viremia 42 renal disease 41 alcoholic hepatitis 41 chronic active hepatitis 41 dyslipidemia 38 alcoholic cirrhosis 36 ischemia 36 infectious diseases 34 heart failure 34 HCV coinfection 34 psoriasis 33 rheumatoid arthritis 33 varices 33 carcinoma 33 tumor growth 33 anemia 33 hyperglycemia 32 alcoholism 31 Chronic hepatitis B 30 hyperlipidemia 28 malnutrition 26 hepatic encephalopathy 25 chronic disease 25 thalassemia 25 Schistosoma mansoni infection 25 biliary obstruction 24 thrombocytopenia 23 renal failure 23 sepsis 22 NS3 22 more...

Symptom hepatomegaly 62 splenomegaly 53 overweight 29 pain 29 ataxia 15 hepatosplenomegaly 14 fatigue 14 diarrhea 14 HSA 11 exhaustion 11 abdominal pain 10 weakness 10 Stiffness 9 anesthesia 9 hypotonia 8 seizures 7 starvation 6 discomfort 5 arthralgia 5 discomfort 5 cough 5 cerebellar ataxia 4 regurgitation 4 anorexia 3 respiratory distress 3 collapse 3 erythema 3 vomiting 3 angina 3 polydipsia 2 leg edema 2 nausea 2 loss of balance 2 tremor 2 dyspnea 2 dystonia 2 cachexia 2 pallor 2 dark urine 2 polyuria 2 tenesmus 1 stigma 1 flushing 1 functional recovery 1 frequent urination 1 myalgia 1 chest pain 1 hypoproteinemia 1 abdominal discomfort 1 hunger 1 neuralgia 1 agitation 1 night sweats 1 apathy 1 hyperoxia 1 general problem 1 sleepiness 1 lethargy 1 dysarthria 1 hypercapnia 1 skin damage 1 emaciation 1 Balding 1 enuresis 1 headache 1 right upper quadrant pain 1 skin irritation 1 Spots 1 Anoxia 1 Ill 1

Drug ROS 43 ROC 36 Portal 35 vitamin E 30 IFN-gamma 25 Monit 21 lysine 21 Ethanol 19 Angiotensin II 19 Dermatol 17 CCL 16 ascorbate 16 IL-2 15 caffeine 14 Sorafenib 14 Biopolymers 14 Vitamin A 12 Activin 8 Vitamin E 8 Albumin 8 Emodin 7 Kenyan 7 Emodin 7 Cardiovasc 6 Glutathione 6 Serum albumin 6 Retinoic acid 6 p75 5 MAP 5 Pirfenidone 5 Gel 5 Fructose 5 Gelatin 4 CSF 4 Amiloride 4 ETA 4 uPA 4 Dial 4 Tenofovir 4 PMPA 4 ABC 4 Ginseng 4 EPI 4 Secretin 3 Rituximab 3 Spectrum 3 Ezetimibe 3 Imatinib 3 Parkin 3 Infliximab 3 ETS 3 NOV 3 Simvastatin 3 Glycyrrhiza 3 ATV 3 citric acid 3 Glucagon 3 Infliximab 3 Leaf 3 IFN-beta 3 PFT 3 Parkin 3 Liraglutide 3 PTC 2 Swertia 2 Histamine 2 Nephron 2 Rimonabant 2 Aloe 2 Cilostazol 2 Zileuton 2 Artesunate 2 Verteporfin 2 BH4 2 TiO2 2 Myricetin 2 Gleevec 2 RFP 2 Nephron 2 GEO 2 more...

Enzyme alanine aminotransferase 736 aspartate aminotransferase 635 mitogen-activated protein kinase 227 AST 207 collagenase 145 alkaline phosphatase 141 superoxide dismutase 137 ERK 135 caspase-3 100 gamma-glutamyl transpeptidase 97 luciferase 80 protein kinase 64 catalase 63 renin 58 type III procollagen 54 glutathione peroxidase 49 focal adhesion kinase 47 AMP-activated protein kinase 42 lactate dehydrogenase 34 NADPH oxidase 34 NADPH oxidase 33 peroxidase 31 AMPK 31 AMPK 31 glutathione S-transferase 31 prolyl hydroxylase 30 reverse transcriptase 26 ACE 25 PARP 24 interstitial collagenase 23 urokinase-type plasminogen activator 22 MMP 22 phosphatidylinositol 3-kinase 21 caspase-1 18 lysyl oxidase 18 protein kinase C 18 thrombin 15 MEK 14 matrix metalloproteinase 2 14 caspase-8 13 MMP-3 13 trypsin 12 matrix metalloproteinase 9 12 proteasome 12 alcohol dehydrogenase 12 caspase-9 11 cholinesterase 11 IKK 10 aldehyde dehydrogenase 10 transglutaminase 10 acetylcholinesterase 10 heme oxygenase 10 RNase 10 APC 10 NQO1 10 lipase 9 RNase 9 NOS 9 ceruloplasmin 9 plasmin 8 ACS 8 phosphodiesterase 8 aldehyde dehydrogenase 7 transcriptase 7 aldehyde dehydrogenase 7 aldehyde dehydrogenase 7 aldehyde dehydrogenase 7 glutamine synthetase 7 xanthine oxidase 7 RNA polymerase 7 GSK 7 cdc2 7 NO synthase 6 chymase 6 guanylate cyclase 6 demethylase 6 ATPase 6 tissue plasminogen activator 6 phosphoinositide 3-kinase 6 calcineurin 6 more...

Compound Dec 499 Clin 492 CCl4 477 DNA 379 oxygen 232 TNF 227 ethanol 195 hyaluronic acid 180 iron 177 glucose 169 water 165 Collagen 122 GSH 106 GSH 106 methionine 101 phosphate 62 nitric oxide 62 retinol 58 calcium 53 sodium 52 ASA 52 PEG 51 aldehyde 48 TAA 44 alanine 43 PEG 42 proline 42 MTT 42 acetaldehyde 41 galactose 38 retinoic acid 37 zinc 37 ATP 36 ALP 35 MDA 34 urea 34 cysteine 33 hydrogen 33 vitamin D 33 Angiotensin II 32 Insulin 32 Curcumin 32 acetate 32 tyrosine 30 arginine 30 copper 27 lysine 26 DMN 25 creatinine 25 aldehyde 25 salt 24 N-acetylcysteine 22 Ang II 21 Hydroxyproline 20 cAMP 20 Hematoxylin 19 Silymarin 19 nitrogen 18 Resveratrol 16 GPT 16 leucine 16 His 16 dUTP 16 Vitamin D 16 CAT 16 CAT 16 CAT 16 Ribavirin 16 DEN 15 tryptophan 15 sulfate 15 Cardiol 14 NADPH 14 Melatonin 14 bromide 14 NADPH 14 Methotrexate 14 caffeine 14 nicotinamide 14 methanol 13 more...

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