Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0239946 (liver fibrosis)
8,268 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein collagen 1627 Mol 597 SMA 591 Sep 490 smooth muscle actin 480 aspartate aminotransferase 445 alanine aminotransferase 416 cytokine 356 interferon 329 insulin 279 TNF 227 AST 207 albumin 200 tumor necrosis factor 193 alpha-smooth muscle actin 192 matrix metalloproteinase 160 type I collagen 159 FIB 158 Smad3 150 IL-6 149 HSC 149 platelet-derived growth factor 145 fibronectin 144 alkaline phosphatase 141 Smad2 135 caspase-3 131 IFN 129 EPA 125 superoxide dismutase 103 GSH 102 PDGF 100 CD4 94 TGF-beta 92 serum albumin 91 connective tissue growth factor 89 IL-10 86 gut 84 TLR4 83 MMP-2 81 chemokine 77 more...

Disease liver fibrosis 8268 cirrhosis 2386 liver disease 1138 hepatocellular carcinoma 1026 chronic hepatitis 891 hepatitis C 743 chronic liver disease 565 fatty liver 512 cancer 375 hepatitis B 353 portal hypertension 316 hepatitis 294 obesity 268 viral hepatitis 259 tumor 244 diabetes 238 Nonalcoholic fatty liver 232 liver cancer 228 cholestasis 211 schistosomiasis 209 alcoholic fatty liver 201 liver cancer 181 HIV 181 metabolic syndrome 163 virus infection 150 type 2 diabetes 116 GSH 102 immunodeficiency 101 carcinogenesis 99 Schistosoma mansoni 96 iron overload 90 Schistosoma japonicum 87 Cirrhosis 81 hypertension 78 biliary atresia 70 primary biliary cirrhosis 70 Chronic hepatitis C 68 alcohol abuse 68 tumorigenesis 65 Hepatocellular carcinoma 62 more...

Symptom hepatomegaly 62 splenomegaly 53 overweight 29 pain 29 ataxia 15 diarrhea 14 fatigue 14 hepatosplenomegaly 14 exhaustion 11 HSA 11 abdominal pain 10 weakness 10 Stiffness 9 anesthesia 9 hypotonia 8 seizures 7 starvation 6 discomfort 5 arthralgia 5 discomfort 5 cough 5 regurgitation 4 cerebellar ataxia 4 collapse 3 respiratory distress 3 anorexia 3 erythema 3 vomiting 3 angina 3 polyuria 2 dark urine 2 polydipsia 2 dystonia 2 pallor 2 leg edema 2 tremor 2 cachexia 2 dyspnea 2 loss of balance 2 nausea 2 more...

Drug ROS 43 ROC 36 Portal 35 vitamin E 30 IFN-gamma 25 Monit 21 lysine 21 Ethanol 19 Angiotensin II 19 Dermatol 17 CCL 16 ascorbate 16 IL-2 15 Sorafenib 14 Biopolymers 14 caffeine 14 Vitamin A 12 Activin 8 Vitamin E 8 Albumin 8 Emodin 7 Emodin 7 Kenyan 7 Serum albumin 6 Cardiovasc 6 Retinoic acid 6 Glutathione 6 MAP 5 Gel 5 Pirfenidone 5 Fructose 5 p75 5 Tenofovir 4 Dial 4 Amiloride 4 PMPA 4 Gelatin 4 uPA 4 CSF 4 ETA 4 more...

Enzyme alanine aminotransferase 736 aspartate aminotransferase 635 mitogen-activated protein kinase 227 AST 207 collagenase 145 alkaline phosphatase 141 superoxide dismutase 137 ERK 135 caspase-3 100 gamma-glutamyl transpeptidase 97 luciferase 80 protein kinase 64 catalase 63 renin 58 type III procollagen 54 glutathione peroxidase 49 focal adhesion kinase 47 AMP-activated protein kinase 42 NADPH oxidase 34 lactate dehydrogenase 34 NADPH oxidase 33 AMPK 31 AMPK 31 peroxidase 31 glutathione S-transferase 31 prolyl hydroxylase 30 reverse transcriptase 26 ACE 25 PARP 24 interstitial collagenase 23 urokinase-type plasminogen activator 22 MMP 22 phosphatidylinositol 3-kinase 21 protein kinase C 18 caspase-1 18 lysyl oxidase 18 thrombin 15 matrix metalloproteinase 2 14 MEK 14 caspase-8 13 more...

Compound Dec 499 Clin 492 CCl4 477 DNA 379 oxygen 232 TNF 227 ethanol 195 hyaluronic acid 180 iron 177 glucose 169 water 165 Collagen 122 GSH 106 GSH 106 methionine 101 nitric oxide 62 phosphate 62 retinol 58 calcium 53 ASA 52 sodium 52 PEG 51 aldehyde 48 TAA 44 alanine 43 MTT 42 PEG 42 proline 42 acetaldehyde 41 galactose 38 retinoic acid 37 zinc 37 ATP 36 ALP 35 urea 34 MDA 34 cysteine 33 hydrogen 33 vitamin D 33 Insulin 32 more...

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