Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0239946 (
liver fibrosis
)
8,268
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
collagen
1627
Mol
597
SMA
591
Sep
490
smooth muscle actin
480
aspartate aminotransferase
445
alanine aminotransferase
416
cytokine
356
interferon
329
insulin
279
TNF
227
AST
207
albumin
200
tumor necrosis factor
193
alpha-smooth muscle actin
192
matrix metalloproteinase
160
type I collagen
159
FIB
158
Smad3
150
IL-6
149
more...
Disease
liver fibrosis
8268
cirrhosis
2386
liver disease
1138
hepatocellular carcinoma
1026
chronic hepatitis
891
hepatitis C
743
chronic liver disease
565
fatty liver
512
cancer
375
hepatitis B
353
portal hypertension
316
hepatitis
294
obesity
268
viral hepatitis
259
tumor
244
diabetes
238
Nonalcoholic fatty liver
232
liver cancer
228
cholestasis
211
schistosomiasis
209
more...
Symptom
hepatomegaly
62
splenomegaly
53
pain
29
overweight
29
ataxia
15
diarrhea
14
hepatosplenomegaly
14
fatigue
14
exhaustion
11
HSA
11
abdominal pain
10
weakness
10
Stiffness
9
anesthesia
9
hypotonia
8
seizures
7
starvation
6
cough
5
arthralgia
5
discomfort
5
more...
Drug
ROS
43
ROC
36
Portal
35
vitamin E
30
IFN-gamma
25
lysine
21
Monit
21
Angiotensin II
19
Ethanol
19
Dermatol
17
ascorbate
16
CCL
16
IL-2
15
caffeine
14
Sorafenib
14
Biopolymers
14
Vitamin A
12
Vitamin E
8
Albumin
8
Activin
8
more...
Enzyme
alanine aminotransferase
736
aspartate aminotransferase
635
mitogen-activated protein kinase
227
AST
207
collagenase
145
alkaline phosphatase
141
superoxide dismutase
137
ERK
135
caspase-3
100
gamma-glutamyl transpeptidase
97
luciferase
80
protein kinase
64
catalase
63
renin
58
type III procollagen
54
glutathione peroxidase
49
focal adhesion kinase
47
AMP-activated protein kinase
42
NADPH oxidase
34
lactate dehydrogenase
34
more...
Compound
Dec
499
Clin
492
CCl4
477
DNA
379
oxygen
232
TNF
227
ethanol
195
hyaluronic acid
180
iron
177
glucose
169
water
165
Collagen
122
GSH
106
GSH
106
methionine
101
phosphate
62
nitric oxide
62
retinol
58
calcium
53
ASA
52
more...