Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0239182 (Watery diarrhea)
 34 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Gnotobiotic pigs were orally exposed to various anaerobes at 6 to 9 days of age and similarly inoculated with Treponema hyodysenteriae B204 3 to 6 days later. Watery diarrhea and fecal excretion of large quantities of mucus and some fibrin clots were observed 4 to 20 days after inoculation with B204 if other anaerobes were present. Colonic lesions characteristic of swine dysentery were observed when B204 was present with Fusobacterium necrophorum, three strains of Bacteroides vulgatus, a Clostridium species, and Listeria denitrificans individually and when some of these microbes were present in various combinations, but not when B204 was present alone. These results are consistent with the conclusion that T. hyodysenteriae is the primary pathogen in the etiology of swine dysentery and that the presence of one or more other anaerobes is a prerequisite for expression of pathogenicity of T. hyodysenteriae. This prerequisite can be met by a variety of anaerobes.
Infect Immun 1979 Dec
PMID:Pathogenic synergism between Treponema hyodysenteriae and other selected anaerobes in gnotobiotic pigs. 52 47

The worst flood in the history of Bangladesh affected millions of people in 1988. To determine morbidity and mortality during the flood, we investigated the causes of illness in 46,740 patients and causes of death in 154 persons while providing medical relief services in 72 flood affected upazilas (sub-districts). Diarrhoea was the most common illness (34.7%), followed by respiratory tract infections (17.4%). Watery diarrhoea was the most common type (47%) of diarrhoea and the most common cause of death for all age groups except those above 45-years of age. Respiratory disease was responsible for 13% of all reported deaths; only 7% of these were associated with acute respiratory tract infections. Accidental deaths accounted for 9.7% of the reported deaths: 5.8% of those were due to drowning, a figure twice as high as that reported previously. Our study suggests that floods have influenced the distribution of disease and death among the affected population.
J Diarrhoeal Dis Res 1991 Dec
PMID:1988 floods in Bangladesh: pattern of illness and causes of death. 180 May 61

A retrospective review of the records of 724 children under 5 years of age admitted to Port Moresby General Hospital (Papua New Guinea) in 1992-93 with diarrhea was conducted, with emphasis on risk factors for persistent diarrhea. These cases represented 84% of total under-5 diarrhea admissions during the study period. Of the 720 children for which the duration of diarrhea was recorded, 144 (20%) had persistent diarrhea lasting 14 or more days. 49% of persistent diarrhea cases involved children 12-23 months of age; the largest proportion (40%) of short-term diarrhea cases occurred in infants 0-11 months old. Watery diarrhea, vomiting, cough, and fever were the most common presenting symptoms for diarrhea and acute respiratory tract infection was the most frequent cause of co-morbidity. Seasonal peaks in incidence occurred in May-July and November-January. After adjustment for dehydration-related weight loss, 42% of children with diarrhea were classified as malnourished. The case fatality rate was 4.9% for persistent diarrhea and 3.6% for non-persistent cases. In the univariate analysis, age and nutritional status were the only significant risk factors for persistent diarrhea; sex, past hospital admission, and co-morbidity were only weakly associated with persistent diarrhea. In the logistic regression analysis, only malnutrition remained a significant risk factor (odds ratio, 2.7; 95% confidence interval, 1.8-4.0). It is speculated that malnutrition associated with weaning accounts for the high rate of persistent diarrhea among children 12-23 months of age.
P N G Med J 1995 Dec
PMID:Persistent diarrhoea in children admitted to Port Moresby General Hospital. 952 67