Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0238111 (Lennox-Gastaut syndrome)
 861 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 67
ACTH 21
GABA 18
MRI 16
Pol 11
Rett syndrome 10
adrenocorticotropic hormone 9
AED 8
SCN1A 7
beta-endorphin 7
STXBP1 7
cytochrome P450 6
LGS 6
CYP2C19 6
CBD 6
GABRB3 6
asymmetrical 5
REM 5
CHD2 5
She 5
X-linked 5
GABRA1 4
sodium channel 4
CYP3A4 4
KCNT1 4
CSF 3
DNM1 3
TSC1 3
CLB 3
GTPase 3
Thyrotropin-releasing hormone 3
GPR55 3
NMDA receptor 3
P-glycoprotein 3
GABA transaminase 3
thyrotropin-releasing hormone 3
TSC2 3
HLA 3
IQSEC2 2
dynamin 1 2
more...
Disease
Lennox-Gastaut syndrome 861
Lennox-Gastaut syndrome 694
epilepsy 583
West 184
encephalopathy 127
Syndrome 56
status epilepticus 53
mental retardation 41
mental retardation 39
tuberous sclerosis 37
complex partial seizures 33
fits 27
juvenile myoclonic epilepsy 26
Landau-Kleffner syndrome 26
developmental delay 20
cognitive impairment 20
focal epilepsy 19
Ohtahara syndrome 19
Cannabis 17
encephalitis 15
temporal lobe epilepsy 15
rash 13
autism 13
petit mal 13
aplastic anemia 11
Rett syndrome 11
dysplasia 11
confusion 10
multiple sclerosis 9
Alzheimer's disease 9
Down syndrome 9
depression 8
myoclonus epilepsy 8
AIC 8
generalized seizure 8
cerebral palsy 8
atonic seizure 7
aggression 7
febrile convulsions 7
intellectual impairment 7
more...
Symptom
seizures 647
sleepiness 48
dizziness 18
headache 18
ataxia 18
vomiting 16
myoclonus 15
fatigue 14
hypotonia 13
anorexia 12
pain 11
nausea 11
tonic seizure 11
insomnia 10
anesthesia 9
spasm 9
diarrhea 8
partial seizure 7
decreased appetite 6
spasticity 6
tremor 5
hoarseness 4
tonic-clonic seizure 4
agitation 3
cough 3
hemiplegia 3
nausea and vomiting 3
drooling 3
asthenia 2
Poor sleep 1
functional recovery 1
dyspnea 1
dystonia 1
hypertonia 1
tingling 1
alexithymia 1
syncope 1
eds 1
neuralgia 1
ataxic gait 1
more...
Drug
Rufinamide 45
Zonisamide 9
Gabapentin 9
CSF 3
Stiripentol 3
Prednisolone 3
Sodium valproate 2
Monit 2
THF 2
Felbatol 2
Topamax 2
pyridoxal phosphate 2
Pregabalin 1
ROS 1
DBS 1
Vitamin B 1
Zoledronic acid 1
Everolimus 1
Cortrosyn 1
Ganaxolone 1
Frontal 1
lactose 1
Thiopentone 1
Anexate 1
Prednisone 1
Sulthiame 1
Cortrosyn 1
9-THC 1
Pyridoxal phosphate 1
Zonegran 1
Fosphenytoin 1
Enzyme
CYP3A4 4
P-glycoprotein 3
GABA transaminase 3
dihydropteridine reductase 2
ACS 2
tyrosine hydroxylase 2
complex I 2
transglutaminase 1
enolase 1
triphosphatase 1
sialyltransferase 1
pyruvate dehydrogenase 1
ATPase 1
aspartate aminotransferase 1
CYP46A1 1
superoxide dismutase 1
pyruvate dehydrogenase 1
xanthine oxidase 1
sialyltransferase 1
sialyltransferase 1
alanine aminotransferase 1
CPS 1
carboxylesterase 1
glutamate decarboxylase 1
PHT 1
catalase 1
tryptophan hydroxylase 1
pyruvate dehydrogenase 1
glutamine synthetase 1
Compound
Clin 72
Dec 54
sodium 39
Felbamate 30
Lamotrigine 28
ACTH 22
Clobazam 22
Cannabidiol 19
GABA 18
GABA 18
Vigabatrin 17
Topiramate 15
Valproic acid 12
calcium 11
potassium 10
glucose 10
Zonisamide 9
gamma-aminobutyric acid 8
water 8
glutamate 8
Oxcarbazepine 7
acetate 7
His 6
AY9944 6
2-phenyl-1,3-propanediol 4
galactose 4
Levetiracetam 4
Retard 4
DNA 4
Optimal 3
Neurotol 3
bromide 3
Prednisolone 3
5-HT 3
TRH 3
NMDA 3
oxygen 2
vinyl 2
PLP 2
Luminal 2
more...