Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0238111 (
Lennox-Gastaut syndrome
)
861
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
67
ACTH
21
GABA
18
MRI
16
Pol
11
Rett syndrome
10
adrenocorticotropic hormone
9
AED
8
STXBP1
7
SCN1A
7
beta-endorphin
7
GABRB3
6
CBD
6
CYP2C19
6
cytochrome P450
6
LGS
6
REM
5
X-linked
5
asymmetrical
5
She
5
more...
Disease
Lennox-Gastaut syndrome
861
Lennox-Gastaut syndrome
694
epilepsy
583
West
184
encephalopathy
127
Syndrome
56
status epilepticus
53
mental retardation
41
mental retardation
39
tuberous sclerosis
37
complex partial seizures
33
fits
27
Landau-Kleffner syndrome
26
juvenile myoclonic epilepsy
26
cognitive impairment
20
developmental delay
20
focal epilepsy
19
Ohtahara syndrome
19
Cannabis
17
temporal lobe epilepsy
15
more...
Symptom
seizures
647
sleepiness
48
ataxia
18
dizziness
18
headache
18
vomiting
16
myoclonus
15
fatigue
14
hypotonia
13
anorexia
12
tonic seizure
11
pain
11
nausea
11
insomnia
10
anesthesia
9
spasm
9
diarrhea
8
partial seizure
7
decreased appetite
6
spasticity
6
more...
Drug
Rufinamide
45
Zonisamide
9
Gabapentin
9
CSF
3
Stiripentol
3
Prednisolone
3
pyridoxal phosphate
2
Monit
2
Felbatol
2
Topamax
2
Sodium valproate
2
THF
2
Pregabalin
1
ROS
1
DBS
1
Vitamin B
1
Zoledronic acid
1
Everolimus
1
Ganaxolone
1
Cortrosyn
1
more...
Enzyme
CYP3A4
4
P-glycoprotein
3
GABA transaminase
3
dihydropteridine reductase
2
tyrosine hydroxylase
2
complex I
2
ACS
2
transglutaminase
1
enolase
1
triphosphatase
1
xanthine oxidase
1
pyruvate dehydrogenase
1
pyruvate dehydrogenase
1
aspartate aminotransferase
1
CYP46A1
1
superoxide dismutase
1
glutamate decarboxylase
1
alanine aminotransferase
1
PHT
1
tryptophan hydroxylase
1
more...
Compound
Clin
72
Dec
54
sodium
39
Felbamate
30
Lamotrigine
28
Clobazam
22
ACTH
22
Cannabidiol
19
GABA
18
GABA
18
Vigabatrin
17
Topiramate
15
Valproic acid
12
calcium
11
potassium
10
glucose
10
Zonisamide
9
gamma-aminobutyric acid
8
glutamate
8
water
8
more...