Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0235886 (leg edema)
 674 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
She 66
Sep 49
serum albumin 24
albumin 19
IgA 13
C-reactive protein 12
calcium channel 10
MRI 7
vascular endothelial growth factor 7
beta-endorphin 6
adrenocorticotropic hormone 6
insulin 5
myeloperoxidase 5
hemoglobin 5
natriuretic peptide 4
serum protein 4
alpha-1 antitrypsin 4
fibrinogen 4
protein C 4
lactate dehydrogenase 4
CD20 3
chronic renal failure 3
renin 3
ACTH 3
CHOP 3
Gen 3
prostate-specific antigen 3
ESR 3
lymphoid 3
collagen 3
HLA 2
Polymerase 2
alanine aminotransferase 2
alpha-fetoprotein 2
ANOVA 2
IgE 2
SS-A 2
AFP 2
thromboplastin 2
PAP 2
BNP 2
Albumin 2
prolactin 2
surface antigen 2
angiotensin II receptor 2
IL-6 2
CEAP 2
TRH 2
APC 2
MEFV 2
somatostatin 2
interleukin-2 receptor 2
CRP 2
creatine kinase 2
granulocyte colony-stimulating factor 2
VEGF 2
LDH 2
proteinase 3 2
interferon 2
prostate specific antigen 2
axonal 2
alkaline phosphatase 2
asymmetrical 2
tyrosine kinase 2
Spin 2
mTOR 2
atrial natriuretic peptide 2
ACE 2
LHRH 2
FDG 2
thyroid hormone 2
cage 1
Myeloperoxidase 1
thyroid transcription factor-1 1
CRH 1
stromelysin 1
MLH1 1
amylase 1
CXCR3 1
Sotos syndrome 1
leukocyte antigen 1
non-Hodgkin's lymphoma 1
thymus 1
megalin 1
COP 1
interferon-alpha 1
Men 1
cathepsin G 1
interleukin-4 1
vascular endothelial growth factor A 1
SEMG 1
angiotensin II 1
PROS1 1
extracellular protein 1
AML 1
PLA 1
androgen receptor 1
cytochrome P450 1A2 1
CD103 1
alpha 1-antitrypsin 1
CXCL9 1
interleukin-6 1
EAD 1
lacrimal 1
protein S 1
mast cell tryptase 1
IVA 1
DR5 1
Lp(a) 1
CD56 1
RNP 1
PRL 1
RAGE 1
TTR protein 1
tap 1
MTF 1
granulocyte 1
antithrombin III 1
CEA 1
CPS 1
carcinoembryonic antigen 1
MTM 1
CD8 1
SS-B 1
NAG 1
CD68 1
X-linked 1
por 1
CYP3A4 1
xCT 1
IgG3 1
platelet-derived growth factor receptor 1
enigma 1
sit 1
NIDDM 1
CD4 1
serum amyloid A protein 1
titin 1
HSA 1
chromogranin A 1
IgA1 1
transthyretin 1
GM-CSF 1
bcl-2 1
PSA 1
phosphatase 1
mucin 1
cytochrome P450 1
phosphodiesterase 1
cytokine 1
epidermal growth factor receptor 1
pT3 1
M-protein 1
NOD 1
adenosine deaminase 1
KvLQT1 1
AII 1
heavy chain 1
HRAS 1
cytokeratin 1
more...
Disease
tumor 66
heart failure 59
proteinuria 52
hypertension 52
deep vein thrombosis 41
cancer 39
nephrotic syndrome 35
lymphedema 34
venous insufficiency 26
glomerulonephritis 23
varices 23
anemia 20
metastases 20
pericarditis 18
vasculitis 17
pericardial effusion 17
diabetes 16
pulmonary embolism 15
lymphadenopathy 15
carcinoma 15
ischemia 14
protein-losing enteropathy 14
pulmonary hypertension 14
obesity 13
cirrhosis 13
hepatocellular carcinoma 13
hydronephrosis 13
congestive heart failure 13
systemic lupus erythematosus 12
amyloidosis 12
renal disease 11
thrombocytopenia 11
renal insufficiency 11
Budd-Chiari syndrome 11
polyneuropathy 10
pneumonia 10
lymphoma 10
membranous nephropathy 10
lymphocele 10
renal failure 9
rare disease 9
Parkinson's disease 8
rheumatoid arthritis 8
hypothyroidism 8
POEMS syndrome 8
hepatitis 8
pulmonary edema 8
gammopathy 8
leg ulcers 8
adenocarcinoma 8
breast cancer 8
cellulitis 7
tuberculosis 7
endocarditis 7
atherosclerosis 7
gastrointestinal disease 7
prostate cancer 7
purpura 7
filariasis 7
sarcoma 7
Cushing's syndrome 7
leiomyosarcoma 6
cystitis 6
respiratory failure 6
infectious diseases 6
abdominal aortic aneurysm 6
cold 6
gangrene 6
chronic stable angina 6
myocardial infarction 6
B-cell lymphoma 6
multiple myeloma 6
portal hypertension 6
ureter 6
esophageal varices 6
hepatitis C 6
beriberi 5
stroke 5
arthritis 5
eosinophilia 5
confusion 5
liver disease 5
nephritis 5
lupus 5
antiphospholipid syndrome 5
compartment syndrome 5
squamous cell carcinoma 5
neuropathy 5
sleep apnea 5
prostatic adenocarcinoma 5
type 2 diabetes 5
malnutrition 5
hepatitis B 5
incontinence 5
stasis dermatitis 5
dysplasia 5
depression 5
ventricular septal defect 5
hallucinations 5
lupus nephritis 5
Kaposi's sarcoma 4
lymphatic vessels 4
mitral regurgitation 4
sepsis 4
glomerulosclerosis 4
coronary artery disease 4
proctitis 4
aortic aneurysm 4
right heart failure 4
lung metastases 4
acute renal failure 4
asthma 4
peripheral vascular disease 4
disseminated intravascular coagulation 4
AA amyloidosis 4
thymoma 4
atrioventricular block 4
ventricular hypertrophy 4
sepsis 4
erysipelas 4
renal impairment 4
cervical cancer 4
hypoglycemia 4
malabsorption 4
lymphopenia 4
chronic hepatitis 4
yellow nail syndrome 4
heart disease 4
pruritus 4
lupus 4
hyperthyroidism 4
chronic obstructive pulmonary disease 4
rash 4
leukopenia 4
hyperglycemia 3
Takayasu 3
leiomyoma 3
hyperlipidemia 3
sarcoidosis 3
Klippel-Trenaunay syndrome 3
mesothelioma 3
postphlebitic syndrome 3
Hodgkin's disease 3
preeclampsia 3
HIV 3
liposarcoma 3
claudication 3
scrotum 3
tricuspid regurgitation 3
elephantiasis 3
cardiomyopathy 3
hyperphagia 3
Prostate Cancer 3
bone metastases 3
coagulopathy 3
cardiac tamponade 3
renal cell carcinoma 3
thiamine deficiency 3
scoliosis 3
wasting 3
more...
Symptom
leg edema 674
dyspnea 80
pain 49
fatigue 28
abdominal pain 26
weakness 23
diarrhea 21
exertional dyspnea 14
chest pain 14
hypoproteinemia 11
shortness of breath 11
dizziness 11
hepatomegaly 11
headache 11
sleepiness 10
discomfort 10
discomfort 10
angina 9
numbness 9
orthopnea 8
erythema 7
Ill 6
anorexia 6
arthralgia 6
flushing 6
vomiting 6
hepatosplenomegaly 6
nausea 6
abdominal fullness 5
back pain 5
cough 5
leg pain 5
cyanosis 5
regurgitation 4
lightheadedness 4
syncope 3
Cushingoid 3
fever of unknown origin 3
paresthesia 3
asthenia 3
flank pain 3
Cushingoid 3
hot flushes 3
anesthesia 3
pedal edema 3
oliguria 3
dysuria 2
blurred vision 2
chyluria 2
tingling 2
pelvic pain 2
myalgia 2
hip pain 2
respiratory distress 2
hemoptysis 2
overweight 2
polyuria 2
rales 2
pleuritic chest pain 2
groin pain 2
abdominal discomfort 2
low back pain 2
epigastric pain 2
rhinorrhea 1
dysesthesia 1
dysarthria 1
presyncope 1
paresis 1
localized edema 1
emaciation 1
neuralgia 1
excessive sweating 1
memory loss 1
tachypnea 1
collapse 1
workaholic 1
prostatism 1
HSA 1
livedo 1
hypercapnia 1
night sweats 1
knee pain 1
hypothermia 1
cancer pain 1
chills 1
polydipsia 1
lethargy 1
menopausal symptoms 1
muscle cramps 1
Pain at rest 1
sciatica 1
shoulder pain 1
clonus 1
tense 1
swollen leg 1
limb pain 1
persistent cough 1
clubbing 1
hypotonia 1
nausea and vomiting 1
snoring 1
splenomegaly 1
Orthostasis 1
Drug
Dermatol 16
Cardiovasc 15
nitroglycerin 4
Prednisolone 3
Rituximab 3
Methylprednisolone 3
Serum albumin 2
Monit 2
Albumin 2
Portal 2
CTX 2
Lipiodol 1
Clobetasol propionate 1
Triclosan 1
Plaquenil 1
Plaquenil 1
Felodipine 1
Ketoconazole 1
Bortezomib 1
Tocilizumab 1
Bosentan 1
Dial 1
Asthma 1
NAG 1
Isradipine 1
Pramipexole 1
Imatinib 1
Jujube 1
Nephron 1
Cilnidipine 1
IPM 1
caffeine 1
Fluconazole 1
CDZM 1
Mizoribine 1
Herceptin 1
MOF 1
Rosiglitazone 1
Pramipexole 1
Lenalidomide 1
Amifostine 1
CSF 1
Bosentan 1
lysine 1
Tacrolimus 1
Nelumbo seed 1
Nephron 1
Enzyme
APC 6
peroxidase 5
lactate dehydrogenase 4
ACE 3
prostate-specific antigen 3
renin 3
alanine aminotransferase 3
thromboplastin 2
alkaline phosphatase 2
creatine kinase 2
CYP3A4 1
phosphodiesterase 1
alcohol dehydrogenase 1
cathepsin G 1
Alternating 1
phosphomannomutase 1
gamma-glutamyl transpeptidase 1
trypsin 1
tryptase 1
ADH 1
adenosine deaminase 1
xanthine oxidase 1
CPS 1
HDR 1
phospholipase A2 1
P-glycoprotein 1
succinate dehydrogenase 1
calcineurin 1
adenosine deaminase 1
Compound
Clin 61
Dec 52
His 27
Cardiol 26
creatinine 18
water 18
DNA 13
calcium 12
oxygen 7
potassium 7
Mibefradil 6
glucose 6
sodium 5
urea 5
A 71 4
aldosterone 4
Spironolactone 3
Congo red 3
ACTH 3
A 42 3
Isoproterenol 3
Prednisolone 3
Methylprednisolone 3
CTX 2
PAP 2
ANCA 2
PAP 2
prostacyclin 2
acetate 2
silver 2
ethanol 2
BNP 2
arginine 2
salt 2
iodine 2
TRH 2
Nifedipine 2
PAP 2
nitrate 2
PAS 2
Octreotide 2
PAP 2
Amlodipine 2
nitrogen 2
fluorine 2
FK506 1
selenium 1
Ketoconazole 1
Luminal 1
tryptophan 1
Tegafur 1
pentadecanoic acid 1
CBDCA 1
Heparin 1
THE 1
Salix 1
Amifostine 1
nitric oxide 1
coenzyme Q10 1
mercury 1
6-12 1
Warfarin 1
PLA 1
5-FU 1
Hematoxylin 1
galactose 1
noradrenaline 1
Rifampicin 1
Ketanserin 1
Aristolochic acid 1
acetic acid 1
Flavonoid 1
Propranolol 1
pentadecanoic acid 1
AGE 1
Ropinirole 1
Nisoldipine 1
Rutin 1
caffeine 1
homocysteine 1
Thiamine 1
retinol 1
L-DOPA 1
Tegafur 1
Rapamycin 1
CBDCA 1
sulfate 1
DTPA 1
tryptophan 1
tryptophan 1
Pergolide 1
Ergot 1
Dial 1
Guo 1
carbonate 1
tryptophan 1
3TC 1
MDA 1
Guo 1
CO2 1
DSM 1
Cyclosporine 1
chromium 1
lysine 1
Propranolol 1
TNM 1
Pac 1
TSH 1
alcohol dehydrogenase 1
Methimazole 1
phosphate 1