Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0235886 (leg edema)
 674 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

To investigate the early limb oedema after various types of arterial reconstructions 180 patients operated on due to occlusive or aneurysmatic arterial disease were followed by daily circumference measurements of the lower leg. For volume calculations circumference measurements were shown to be well correlated to water displacement volumetry. Femoro-popliteal bypass resulted regularly in a pronounced oedema, significantly more than in any of the other groups. Aortofemoral reconstruction did not lead to significant leg oedema, but all other reconstructions resulted in a volume increase in the symptomatic leg. Following distal reconstruction, patients with popliteal aneurysm and no ischaemia developed the same maximal volume increase as patients with severe ischaemia. Regarding all patients as one group the volume increase was not significantly correlated to the preoperative ankle blood pressure or ankle brachial pressure index. Only after various proximal reconstructions, with a limited postoperative oedema, there was a correlation between the degree of preoperative ischaemia and postoperative volume increase. A successful reconstruction was not necessary for the development of postoperative oedema. A failed distal reconstruction was followed by a significant oedema, although less pronounced than after a successful. Exploration of the vessels without reconstruction also led to a postoperative oedema. The findings indicate that the pathogenesis of postreconstructive oedema is multifactorial. The type of reconstruction is the most important predictive factor and degree of preoperative ischaemia and success of operation are contributing factors.
 ...
PMID:Lower limb oedema after arterial reconstructive surgery. Influence of preoperative ischaemia, type of reconstruction and postoperative outcome. 280 Aug 74

The aim of this study was to present a case of iatrogenic thromboembolectomy-related tibialis anterior false aneurysm (FA) treated with endovascular FA exclusion and anterior leg compartment (ALC) operative decompression and to assess the current management options in posttraumatic leg vessel FAs. A 68-year-old man had a painful pulsating mass in the superior ALC 2 months after a thromboembolectomy was performed during popliteal aneurysm repair. He had been discharged under oral anticoagulation and had ALC manual massages for mild post-revascularization leg edema. Angio-CT showed tibialis anterior injury successfully treated with a covered stent graft, while a residual ALC hematoma was surgically evacuated. Endovascular treatment of tibialis anterior FAs using a covered stent graft is an excellent therapeutic option. After an endovascular procedure, caution must be taken to identify the need for early operative ALC decompression. Current leg vessel FA management should consider both the specific anatomic characteristics of the FA and the possibility of development of delayed compartment syndrome.
...
PMID:Endovascular exclusion coupled with operative anterior leg compartment decompression in a case of postthromboembolectomy tibialis anterior false aneurysm. 2370 80