Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0235290 (bitter taste)
 1,408 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

From the fresh roots of Trichosanthes kirilowii Maxim. var. japonicum Kitam., the following substances were identified: methyl palmitate, palmitic acid, suberic acid, alpha-spinasterol, stigmast-7-en-3 beta-ol, alpha-spinasterol 3-O-beta-D-glucopyranoside, stigmast-7-en-3 beta-ol 3-O-beta-D-glucopyranoside, bryonolic acid, cucurbitacin B, cucurbitacin D, vomifoliol, ethyl alpha-L-arabinofranoside and D-glucose. The bitter taste of Trichosanthes Root was considered to be due to cucurbitacin B and D.
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PMID:[Studies on the constituents of trichosanthes root. I. Constituents of roots of Trichosanthes kirilowii Maxim. var. japonicum Kitam]. 276 Aug 11

From the fresh roots of Trichosanthes cucumeroides Maxim., three new triterpenoid glycosides with a bitter taste were obtained together with methyl palmitate, palmitic acid, alpha-spinasterol, stigmast-7-en-3 beta-ol, alpha-spinasterol 3-O-beta-D-glucopyranoside, stigmast-7-en-3 beta-ol 3-O-beta-D-glucopyranoside and vanillic acid. On the basis of the results of spectral and chemical investigations, these glycosides were characterized as 25-O-beta-D-glucopyranosyl-11-oxocucurbit-5-ene-3 beta,24(R), 25-triol 3-O-alpha-L-rhamnopyranosyl-(1----2)-beta-D-glucopyranosyl-(1----2)-beta -D- glucopyranoside, 25-O-beta-D-(6-O-acetyl)-glucopyranosyl-11-oxocucurbit-5-ene-3 beta,24(R), 25-triol 3-O-alpha-L-rhamnopyranosyl-(1----2)-beta-D-glucopyranosyl(1----2)- beta-D-glucopyranoside and 11-oxocucurbit-5-ene-3 beta,24(R), 25-triol 3-O-alpha-L-rhamnopyranosyl-(1----2)-beta-D-glucopyranosyl-(1----2)- beta-D-glucopyranoside.
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PMID:[Studies on the constituents of trichosanthes root. II. Constituents of roots of Trichosanthes cucumeroides Maxim]. 276 Aug 12