Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0235108 (tense)
 2,176 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The clinical presentation of a congenital mucocele is a blue-gray tense mass located inferior to the medial canthal ligament. The differential diagnosis is that of tumor and encephalocele. Diagnostic modalities such as simple transillumination and ultrasound aid the physician, but dacryocystography confirms the marked lacrimal sac distension. In three infants the sac could not be decompressed by massage, indicating that the canalicular-punctal system as well as the inferior lacrimal system were blocked. When the distended lacrimal sac compresses the two canaliculi and bends them on themselves, there is a functional trapdoor-type block. During the probing of these patients, we felt a snap when the lacrimal syringe was withdrawn from the distended sac. We concluded that this was due to kinking of the canaliculus by the enlarged sac.
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PMID:Radiographic visualization of congenital lacrimal sac mucoceles. 395 4

Seven infants had tense, blue-gray swellings inferior to the medial canthal tendon with otherwise normal-appearing eyelids and puncta. All lacrimal sacs transilluminated and A-scan ultrasonography performed in one case demonstrated a nonloculated cystic cavity. Four (57%) infants had uncomplicated mucoceles. One was treated with massage, and has remained asymptomatic for 14 months. The other three were cured with a single probing and irrigation of the entire lacrimal system. Three (43%) infants had developed erythema of the tissues overlying the swollen lacrimal sacs by the time of referral. Because none of the mucoceles could be decompressed by massage, prompt probing and irrigations were performed in each case. Cultures from the aspirates of all three sacs yielded Staphylococcus organisms. In contrast to the uncomplicated cases, two patients developed recurrences that necessitated additional treatment.
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PMID:Congenital lacrimal sac mucoceles. 709 Dec 74

Ectopic lacrimal gland tissue is most common in the eyelid, conjunctiva, and cornea, but may also be found in the uvea or orbit. A 7-year-old boy developed a mass in the anterior superiomedial orbit close to the trochlea. A superior medial orbitotomy, done when the boy was 9 years old, disclosed a tense, thin-walled, fluid-filled cyst containing a small nest of normal lacrimal gland with a large capsule of fibrous tissue containing areas of singly layered epithelial cells.
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PMID:Ectopic lacrimal gland cyst of the orbit. 727 Jun 33

Lacrimal duct cysts are not common. It is extremely rare when a lacrimal duct cyst and an ectopic lacrimal gland develop in the orbital cavity. A unique case of an ectopic lacrimal gland cyst of the orbit is presented. A 33-year-old man had a palpable mass above the inferior medial orbital rim for nearly two years. An ocular examination was normal except for a movable, firm mass found in the anterior nasal inferior orbit of the right eye. An echogram revealed a homogeneous, hypoechoic cystic mass. Computed tomography of the orbit showed a well-encapsulated lesion in the lower orbit of the right eye near the inferior rectus muscle, without bony erosion. A tense, thin-walled, clear fluid-filled cyst measuring 15 x 12 x 13 mm in size was completely enucleated without rupture by anterior orbitotomy. Pathologic examination disclosed a small nest of normal gland tissue surrounded by a cystic lesion lined with two layers of lacrimal duct epithelium cells. No recurrent signs were noticed during a 12-month period of follow-up.
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PMID:Ectopic lacrimal gland cyst of the orbit. 1082 Sep 14

A previously healthy woman was admitted to the intensive care unit (ICU) with severe H1N1 influenza. She had prolonged hospital stay due to multiple complications of critical illness, including pelvic deep vein thrombosis (DVT), which was treated with subcutaneous enoxaparin. The patient was referred to the ophthalmology service for bilateral proptosis. On examination, she had bilateral tense proptosis, worse on the left side with exposure keratopathy. Laboratory tests showed that she had thrombocytopenia and raised activated partial thromboplastin time (APTT). A CT scan revealed well-circumscribed soft tissue density lesions in the superolateral orbits and was reported as bilateral lacrimal gland enlargement. However, based on a clinical suspicion of subperiosteal hematoma collection, a diagnostic tap was performed. Following aspiration of six mls of dark blood from the left superior orbit, there was a reduction of proptosis with improvement in chemosis and resolution of exposure keratopathy. Enoxaparin is one of several antithrombotic agents which are increasingly being used for DVT prophylaxis in severely compromised patients. Furthermore, ICU patients ventilated for prolonged periods are at risk of developing chemosis and exposure keratopathy. Thus, the clinician should maintain a high index of suspicion in identifying subperiosteal hematomas, when managing such cases. The spontaneous bilateral vision threatening subperiosteal hematoma was probably caused by a combination of enoxaparin therapy and prolonged ventilation.
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PMID:Bilateral orbital haematomas in an anticoagulated patient with severe H1N1 influenza. 2129 3