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Query: UMLS:C0235108 (tense)
 2,176 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Herpes gestationis is a pruritic, blistering disease of pregnancy and the puerperium. The clinical presentation consists of intense itching with widespread erythematous, edematous papules and plaques, grouped vesicles and tense bullae. Through recent advances in the immunopathology of blistering diseases, increased accuracy in the diagnosis of herpes gestationis is now possible.
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PMID:Herpes gestationis. A report of two cases. 638 1

Pemphigoid gestationis is a rare autoimmune blistering disease of pregnancy. It is characterized by pruritic, urticarial plaques with the development of tense vesicles and bullae within the lesions. Pemphigoid gestationis has been associated with premature delivery, small-for-gestational-age infants. Recurrences with subsequent pregnancies are often more severe. Oral glucocorticoids are the mainstay of therapy. Differentiation of pemphigoid gestationis from pruritic urticarial papules and plaques of pregnancy is essential because management and outcomes differ. In instances in which clinical diagnosis is difficult, direct immunofluorescence tests, immunoblots, or ELISA studies of anti-basement-membrane zone antibodies are useful in establishing the diagnosis.
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PMID:Pemphigoid gestationis. 2116 61