Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0234238 (ACHE)
 235 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ACHE 17.0
GYPA/GYPB 17.0
ADCK5 17.0
ENTPD6 15.5
LRRC14 15.5
ZNF169 15.5
Erythroid transcription factor 15.5
GGT6 14.7
ZFR2 14.7
ART4 13.6
ALDH3B2 13.3
ZBTB7B 13.2
MECR 13.1
RAPGEF3 13.1
COLQ 12.9
CHRNA 12.7
KSR2 12.7
RAB21 12.7
GNB2 12.7
alkaline ceramidase 3 12.7
LHFPL5 12.5
ITPKA 12.3
HK3 12.2
PSMA4 12.1
SLC5A7 12.0
PRKAR2B 12.0
plastin 3 12.0
CUTL1 12.0
L-fucokinase 11.9
CHAT 11.8
KEL 11.8
OATP3A1 11.8
ZFHX3 11.7
pristanoyl-CoA oxidase 11.7
ICAM-4 11.7
IMPDH1 11.6
SCD5 11.5
MAPK7 11.4
LAMB1 11.3
SLC14A1 11.3
neurexin 1 11.3
FBXO11 11.3
Charcot-Leyden crystal protein 11.1
TTD 11.0
GASP 11.0
ACADM 11.0
CNR2 10.9
EPHB4 10.9
EVL 10.7
Vasohibin-1 10.6
GIPR 10.4
PRKAG2 10.4
CHRNB4 10.4
CACNA1D 10.4
PRIMA 10.4
GCR 10.3
CHRM2 10.2
ITGB4 10.2
G protein-coupled receptor 30 10.2
NPAS2 10.2
ERCC6 10.1
GSTO1 10.1
hnRNP H 10.0
PLAT 10.0
TEP1 9.8
A4 protein 9.8
PON1 9.8
SLC4A1 9.8
butyrylcholinesterase 9.7
AChE 9.6
MME 9.6
CNR1 9.6
GARP 9.5
CHRNA3 9.5
COXIV 9.5
CEAP 9.4
PPARA 9.4
ADAM12 9.4
MDR3 9.4
ALAD 9.3
FADS2 9.3
ARP 9.2
IMPDH 9.2
acetylcholinesterase 9.2
Isl-1 9.1
TTN 9.0
ACH 9.0
MNS 9.0
pseudocholinesterase 8.9
DLK1 8.9
PON 8.8
Sp1 protein 8.7
NFE2L2 8.6
Cholinesterase 8.6
Islet-1 8.6
Runt-related transcription factor 2 8.6
MACS 8.5
Rheumatoid factor 8.5
PGR 8.5
G6PDH 8.5
Fractalkine 8.5
zebrafish) 8.5
HTR2A 8.5
APOB 8.5
AQP1 8.5
G15 8.4
NOS1 8.4
SGB 8.4
CAE 8.3
MSK 8.3
arylesterase 8.3
UGT1A6 8.3
paraoxonase 1 8.3
PGC-1 8.3
postsynaptic density protein 95 8.3
ASP 8.2
cannabinoid receptor 1 8.1
DPP IV 8.1
Shp2 8.1
nuclear factor of activated T-cells 7.9
MC4R 7.8
ABCC2 7.8
ASL 7.8
IRP 7.8
PTGS2 7.7
PAX6 7.6
Desmin 7.6
CLIP 7.5
vesicular acetylcholine transporter 7.5
PDH 7.5
paraoxonase 7.5
EGR1 7.4
MDH 7.4
COL1A2 7.4
microphthalmia-associated transcription factor 7.3
EGR-1 7.3
Nestin 7.3
carboxylesterase 7.2
small nuclear ribonucleoprotein 7.2
P19 7.2
heat shock protein 27 7.1
YY1 7.1
NOS2 7.1
SP1 7.0
proline-rich 7.0
CA4 6.9
TRPA1 6.9
CYP19 6.9
SDH 6.9
Klotho 6.8
grit 6.7
TPP 6.7
GATA-1 6.7
FTO 6.7
AML1 6.7
DLD 6.7
sirtuin 1 6.7
muscarinic acetylcholine receptor 6.6
CFTR 6.6
FMR1 6.6
motilin 6.5
EPO 6.5
cAMP-response element 6.5
DEAD 6.5
GSTP1 6.4
alternatively spliced 6.4
cAMP response element-binding protein 6.4
CLA 6.3
ERBB2 6.3
WIN 6.3
GSTT1 6.3
FGF2 6.3
AP-2 6.2
SHP-2 6.2
NR2A 6.2
Duffy 6.2
HLA-DRB1 6.2
K10 6.2
B27 6.1
AP2 6.1
C30 6.1
choline acetyltransferase 6.0
GSTM1 6.0
MET 6.0
ACT 6.0
ADH 5.9
NQO1 5.9
thyroglobulin 5.9
AVP 5.8
aryl hydrocarbon receptor 5.8
P-gp 5.7
APOE 5.6
olfactory receptor 5.6
acetylcholine receptor 5.6
PIK3CA 5.6
non-muscle 5.6
ACP 5.5
TdT 5.5
CAT 5.5
brain) 5.5
Rett syndrome 5.5
MyoD 5.5
SIRT1 5.3
SBP 5.3
nicotinic acetylcholine receptor 5.3
OCT 5.3
Catalase 5.2
CD133 5.2
transcriptional factor 5.2
aminopeptidase 5.2
Sp1 5.2
alpha-fetoprotein 5.1
protein tyrosine phosphatase 5.1
megakaryocyte 5.1
cathepsin B 5.0
ALP 5.0
DNA methyltransferase 5.0
p300 5.0
Raf-1 4.9
glutamate dehydrogenase 4.9
DNase 4.9
APP 4.9
neurotrophic factor 4.8
ABO 4.8
vasoactive intestinal peptide 4.8
erythropoietin 4.8
hedgehog 4.8
tau protein 4.7
PDB 4.7
rheumatoid factor 4.7
leptin 4.7
dystrophin 4.7
JAK2 4.6
novel gene 4.6
c-fos 4.6
Leptin 4.6
CD68 4.6
ghrelin 4.5
AST 4.4
plasminogen activator inhibitor-1 4.4
CYP3A4 4.4
peroxisome proliferator-activated receptor gamma 4.3
transmembrane protein 4.2
interacting protein 4.2
esterase 4.2
follicle-stimulating hormone 4.2
PKA 4.2
AML 4.2
HSP70 4.1
tyrosinase 4.1
beta-glucuronidase 4.0
heme oxygenase-1 4.0
DBA 3.9
heat shock protein 3.9
gastrin 3.8
RNase 3.8
xenobiotic 3.7
LDH 3.7
CD44 3.6
Men 3.5
asymmetrical 3.5
NADPH 3.5
mer 3.4
cyclin D1 3.4
COX-2 3.4
IL-17 3.4
cryptic 3.3
GTPase 3.2
5-hydroxytryptamine 3.2
creatine kinase 3.2
tyrosine hydroxylase 3.1
UTR 3.1
catalase 3.1
granulocyte 3.1
VEGF 3.1
thyroid hormone 3.1
telomeric 3.0
calcitonin 3.0
collagen 2.9
cyclooxygenase 2.9
amyloid precursor protein 2.9
olfactory 2.9
endonuclease 2.9
catenin 2.9
GSH 2.8
thymus 2.8
inducible nitric oxide synthase 2.8
erythroid 2.7
glutathione peroxidase 2.7
CSF 2.5
IL-8 2.5
superoxide dismutase 2.5
cytochrome P450 2.4
proteasome 2.4
reductase 2.4
estrogen receptor 2.3
membrane-bound 2.2
nitric oxide synthase 2.2
growth hormone 2.2
vascular endothelial growth factor 2.1
lipopolysaccharide 2.1
MAPK 2.1
hemoglobin 2.1
AMP 1.8
HLA 1.8
peroxidase 1.7
Mol 1.5
TNF 1.1
endoplasmic reticulum 1.1
ATP 1.0
polypeptide 0.9
ACS 0.8
Gen 0.1
cytokine -0.1
Sep -0.1
insulin -0.6
Disease
PLAT 10.0
infectious arthritis 9.2
normocytic anemia 9.2
CAE 9.1
CAE 9.0
MNS 8.7
APOB 8.5
pseudogout 8.5
communication disorder 8.3
SSD 7.9
Zinc deficiency 7.9
achondroplasia 7.6
ERS 7.5
Apert syndrome 7.5
Fallopian tube 7.5
Worms 7.5
HCA 7.2
dysautonomia 7.2
acanthosis nigricans 7.1
major depressive episode 6.9
polymyalgia rheumatica 6.8
seborrheic dermatitis 6.7
Tension 6.5
autoimmune thyroid disease 6.5
pyoderma gangrenosum 6.4
syringomyelia 6.3
hyperostosis 6.3
osteitis 6.2
Autism spectrum disorder 6.0
hyperandrogenism 6.0
ADH 5.9
juvenile rheumatoid arthritis 5.8
congenital adrenal hyperplasia 5.7
ECT 5.7
gout 5.7
acne vulgaris 5.7
trigeminal neuralgia 5.7
emotional stress 5.6
rheumatism 5.6
ACP 5.5
giant cell arteritis 5.4
embryonal carcinoma 5.3
claudication 5.3
septic arthritis 5.3
IBM 5.3
stress incontinence 5.1
erythroleukemia 5.1
goiter 5.1
fibromyalgia 4.9
medulloblastoma 4.8
SLE 4.7
synovitis 4.6
migraine 4.6
paraplegia 4.4
anorexia nervosa 4.4
acne 4.3
neuroticism 4.3
PDB 4.3
Duchenne muscular dystrophy 4.1
wasting 4.1
hypothyroidism 4.1
developmental delay 4.1
worms 4.0
syphilis 4.0
Abuse 4.0
scoliosis 4.0
Graves' disease 3.9
genetic disorder 3.9
ADHD 3.9
Blocking 3.9
chronic disease 3.9
urethra 3.9
DBA 3.7
varices 3.6
Nose 3.6
liver cancer 3.6
myopathy 3.5
brain tumor 3.5
Alzheimer's disease 3.5
aggressiveness 3.5
skin disease 3.4
substance abuse 3.3
addiction 3.3
violence 3.2
myelodysplastic syndrome 3.2
liver cancer 3.2
bacterial infection 3.2
mental illness 3.1
hyperlipidemia 3.1
blindness 3.0
osteoarthritis 2.9
mole 2.9
encephalopathy 2.9
amyotrophic lateral sclerosis 2.8
GSH 2.8
chronic pain 2.8
primary tumor 2.7
mole 2.7
systemic lupus erythematosus 2.6
renal cell carcinoma 2.6
chronic renal failure 2.6
cold 2.6
neuropathy 2.5
inflammatory bowel disease 2.5
lung carcinoma 2.5
metabolic syndrome 2.5
cystic fibrosis 2.4
plaque 2.3
neuroblastoma 2.3
MCF 2.3
cytomegalovirus 2.2
tumorigenesis 2.2
abortion 2.2
glioma 2.1
fits 2.1
Parkinson's disease 2.1
dysplasia 2.1
arthritis 2.0
melanoma 2.0
osteoporosis 1.8
multiple sclerosis 1.7
malaria 1.6
renal disease 1.6
leukemia 1.5
anemia 1.4
sepsis 1.4
rheumatoid arthritis 1.4
depression 1.2
influenza 1.2
tumor growth 1.2
sepsis 1.2
schizophrenia 1.2
obesity 1.1
epilepsy 1.1
cardiovascular disease 1.0
lung cancer 0.9
stroke 0.9
tuberculosis 0.8
breast cancer 0.8
asthma 0.7
tumor 0.2
carcinoma -0.2
cancer -0.4
diabetes -1.0
Symptom
ACHE 17.0
Neurogenic pain 13.1
Burning pain 12.8
Central pain 12.4
elbow pain 8.8
sciatica 6.4
photophobia 6.4
numbness 6.3
twitching 6.1
Wind 5.7
asthenia 5.7
constipation 5.3
back pain 5.1
paresthesia 4.8
insomnia 4.7
paresis 4.5
spasticity 4.4
myalgia 4.4
headache 4.3
arthralgia 4.2
syncope 3.9
distraction 3.9
weakness 3.8
dizziness 3.8
low back pain 3.8
pain 3.1
ataxia 3.1
vomiting 3.1
nausea 2.5
diarrhea 1.2
Drug
Modafinil 8.5
Gabapentin 7.2
THA 7.2
Bayer 6.4
Ginseng 6.4
Diurnal 6.3
ACT 6.0
Retinoic acid 5.3
CAM 4.5
Asn 3.5
vitamin E 2.9
CSF 2.1
Dermatol -1.0
Enzyme
HK3 12.2
acetylcholinesterase 8.6
cholinesterase 8.0
PDH 7.6
MDH 7.4
paraoxonase 7.3
MDH 7.3
paraoxonase 7.0
TPP 6.7
TPP 6.5
carboxylesterase 6.5
choline acetyltransferase 6.0
ADH 5.9
NADPH-diaphorase 5.1
cathepsin B 5.0
glutamate dehydrogenase 5.0
glutamate dehydrogenase 5.0
glutamate dehydrogenase 4.9
malate dehydrogenase 4.9
DNA methyltransferase 4.8
CPR 4.7
monoamine oxidase 4.7
diaphorase 4.5
AST 4.5
NQO1 4.5
CYP3A4 4.4
DNase 4.1
glucose-6-phosphate dehydrogenase 4.1
tyrosinase 3.9
alcohol dehydrogenase 3.9
luciferase 3.8
catalase 3.6
ERK 3.3
tyrosine hydroxylase 3.2
NO synthase 3.1
RNase 3.1
RNase 2.9
ACE 2.9
endonuclease 2.9
creatine kinase 2.8
aspartate aminotransferase 2.6
glutathione peroxidase 2.6
alanine aminotransferase 2.3
protein kinase 2.3
proteasome 2.2
superoxide dismutase 2.2
trypsin 1.7
focal adhesion kinase 1.6
mitogen-activated protein kinase 1.5
protein kinase C 1.5
peroxidase 1.0
ACS 0.8
Compound
Neryl acetate 15.0
vinyl benzoate 12.5
ethyl benzoate 10.6
Cilag 10.6
P2A 9.4
Soman 9.1
methyl benzoate 9.1
Tacrine 8.8
MME 8.6
Imidacloprid 8.1
MAK 7.8
Ach 7.7
TTS 7.6
galanthamine 7.6
SSD 7.5
Uridine 7.4
HCA 7.3
DEP 7.1
PDH 7.1
TPP 6.6
Actinomycin D 6.4
Amphetamine 6.4
Amphetamine 6.4
MMA 6.3
TPP 6.3
TCDD 6.1
Genistein 6.0
4-nitrophenyl 6.0
TPP 5.9
PAM 5.7
Adenine 5.6
isoquinoline 5.5
CAT 5.5
CAT 5.5
2,4-D 5.4
CAT 5.4
PDB 5.2
Salix 5.1
ALP 5.0
ACh 4.9
Collagen 4.9
betaine 4.8
thiourea 4.8
Testosterone 4.5
Testosterone 4.5
retinoic acid 4.1
alcohol dehydrogenase 4.0
Primatol 3.9
DBA 3.9
DBA 3.9
DBA 3.6
asparagine 3.5
NADPH 3.4
NADPH 3.4
COS 3.4
aspartic acid 3.4
uridine 3.4
Thyroid 3.2
hexane 3.1
toluene 2.9
cysteine 2.8
pyrene 2.8
GSH 2.7
GSH 2.7
acetone 2.7
DSM 2.4
EDTA 2.3
EDTA 2.3
cobalt 2.3
cAMP 2.2
methionine 2.2
nickel 2.1
5-HT 2.1
DNA 2.0
acetate 1.8
AMP 1.7
NH2 1.5
PEG 1.3
salt 1.2
phosphate 1.2
methanol 1.2
leucine 1.2
TNF 1.1
ATP 1.0
iron 1.0
ethanol 0.9
galactose 0.9
ACS 0.8
His 0.8
ACS 0.8
calcium 0.7
zinc 0.6
copper 0.5
nitric oxide 0.5
Dec 0.0
water -0.0
nitrogen -0.2
oxygen -0.4
Clin -0.7