Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0233794 (memory impairment)
7,237 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
V-set and transmembrane domain containing 2 like 11.1
GHBR 11.1
SPON1 protein 11.1
AAK1 protein 11.1
LanC-like protein 2 11.1
Beta-site APP-cleaving enzyme 10.1
regulator of G-protein signaling 14 10.1
Vsm-RhoGEF 10.1
GABARAP protein 9.8
hRFI 9.8
GMIP 9.6
paraspeckle protein 1 9.3
Tau-tubulin kinase 9.3
GMFB 9.1
PTGFRN 9.1
DSCR3 9.1
QRFP receptor 9.1
PS23 9.1
septin 5 9.1
calcium/calmodulin-dependent protein kinase II alpha 9.0
FAST kinase 8.9
CREB1 protein 8.9
LGI3 8.9
SPPL2c 8.9
ATP5H 8.9
kallikrein 8 8.8
APMAP 8.8
AP2A2 8.8
advanced glycosylation end product-specific receptor 8.8
QN1 8.6
GALM 8.6
CYH 8.5
stromal interaction molecule 2 8.5
Ran-binding protein 9 8.4
TMEM59 8.4
calmodulin-like skin protein 8.3
voltage gated potassium channel 8.3
FASTKD2 8.3
TTC3 8.2
WLT 8.2
PRPH 8.2
Voltage-gated potassium channel 8.2
WMS 8.2
cytoskeleton associated protein 8.1
NMNAT3 8.1
IDH3A 8.1
APBA2 8.1
M1 muscarinic cholinergic receptor 8.1
Humanin 8.0
TTBK1 8.0
nicotinamide mononucleotide adenylyltransferase 2 8.0
KGDHC 8.0
AD 2 7.9
beta-site APP-cleaving enzyme 7.9
neurotrophic tyrosine kinase receptor type 2 7.9
phosphatidylinositol-binding clathrin assembly protein 7.9
ATG16L 7.9
M-BAR 7.9
glycogen synthase kinase 3 alpha 7.9
PSMB6 7.8
AD 1 7.7
HS3ST1 7.7
Interferon-induced transmembrane protein 3 7.6
cysteinyl leukotriene receptor 1 7.5
PRAP 7.5
SEP15 7.5
centrosomal P4.1-associated protein 7.5
CRHBP 7.5
ADDL 7.4
Death-associated protein kinase 1 7.4
Neuropsin 7.3
KNT 7.3
RPL8 7.3
Tuberoinfundibular peptide of 39 residues 7.3
RAH 7.3
Arg3.1 7.3
14-3-3 eta 7.2
CHSY1 7.2
24-dehydrocholesterol reductase 7.2
BCAT2 7.2
more...
Disease
hyperleucine-isoleucinemia 12.1
Septum pellucidum cyst 12.1
memory impairment 12.1
CNS inflammation or infection 12.1
presbyophrenia 10.8
Bradyphrenia 10.5
hypervalinemia 9.8
Transient epileptic amnesia 9.6
Paranoid delusions 9.5
Age-associated memory impairment 9.5
moria 9.5
Confabulation 9.4
Alzheimer's disease with early onset 9.3
Limbic encephalitis 9.2
Classic polyarteritis nodosa 9.1
Constructional apraxia 9.1
alcoholic Korsakoff's syndrome 9.1
memory disorder 8.9
MCPH6 8.8
loosening of associations 8.8
eccentric personality 8.8
amnesic syndrome 8.7
Postoperative cognitive dysfunction 8.5
absent-mindedness 8.5
Cerebral hypoperfusion 8.5
disturbed memory 8.4
retrograde amnesia 8.3
anterograde amnesia 8.3
unable to remember 8.3
WMS 8.2
WMS 8.2
psychogenic amnesia 8.1
amnesia 8.1
Post-traumatic amnesia 8.1
GTP cyclohydrolase I deficiency 8.1
circumstantiality 8.0
perceptual disturbance 8.0
adult hypothyroidism 7.9
transient global amnesia 7.9
Korsakoff's syndrome 7.9
Autoimmune encephalitis 7.8
Age-related cognitive decline 7.8
Powassan encephalitis 7.8
HIV retinopathy 7.8
Streptococcus pneumoniae meningitis 7.8
cognitive deficit 7.7
Chronic insomnia 7.7
Anton's syndrome 7.6
cognitive disorder 7.5
learning defect 7.5
Diabetic encephalopathy 7.4
Cocaine use disorder 7.3
alcoholic cerebellar degeneration 7.3
anosognosia 7.3
acalculia 7.3
Vascular dementia 7.2
Hippocampal sclerosis 7.2
cognitive impairment 7.2
myofasciitis 7.1
AD3 7.1
Semantic dementia 7.1
Demented 7.0
OBX 7.0
Escherichia coli meningitis 7.0
BPSD 6.9
Extremely low birth weight 6.9
Morvan 6.8
disorientation 6.8
Frontal lobe 6.8
anomia 6.8
Mood disturbances 6.7
pressured speech 6.7
Nicotine withdrawal 6.7
Primary insomnia 6.7
forgetting 6.7
Kluver-Bucy syndrome 6.7
Cortical blindness 6.7
transcortical aphasia 6.7
Unilateral neglect 6.6
Morphine dependence 6.6
more...
Symptom
Rebound insomnia 8.6
amimia 8.2
memory loss 8.2
Drop attacks 7.5
Behavioral symptoms 7.3
Multiple symptoms 7.3
forgetfulness 7.3
personality change 7.0
Prodrome 6.7
feeling depressed 6.6
Psychiatric symptoms 6.6
blackout 5.8
elevated mood 5.4
bewilderment 5.3
hangover 5.2
aphonia 5.2
abnormal gait 5.1
photopsia 5.0
apathy 5.0
visual hallucination 4.9
incoordination 4.9
insomnia 4.8
hypersomnia 4.7
Spastic 4.6
bradykinesia 4.6
clumsiness 4.6
Poor sleep 4.6
jaw pain 4.6
hyperemesis gravidarum 4.6
ataxic gait 4.6
catatonia 4.6
adipsia 4.6
loss of taste 4.6
impaired motor coordination 4.5
disturbed balance 4.3
metamorphopsia 4.2
physical symptom 4.2
acute stress 4.1
lightheadedness 4.1
seizures 4.0
dysarthria 3.9
Gastrointestinal symptoms 3.9
myoclonus 3.8
neurological disability 3.8
despair 3.8
No adverse effect 3.8
Depressive symptoms 3.7
agitation 3.7
meningism 3.7
sleepiness 3.7
intention tremor 3.7
Neuropathic pain 3.6
muscle rigidity 3.6
paraparesis 3.5
Involuntary Movement 3.4
consciousness disturbance 3.4
fasciculation 3.4
dizziness 3.3
cerebellar ataxia 3.3
orthopnea 3.3
ataxia 3.2
motor symptom 3.2
dysesthesia 3.2
orofacial pain 3.2
chorea 3.1
abdominal cramps 3.1
Decreased activity 3.0
functional recovery 3.0
urinary frequency 3.0
mental fatigue 2.9
decreased appetite 2.9
night sweats 2.9
neck stiffness 2.9
tremor 2.7
tonic-clonic seizure 2.7
partial seizure 2.7
vertigo 2.6
distraction 2.6
clonus 2.6
hemiplegia 2.5
more...
Drug
Indeloxazine hydrochloride 10.5
Taltirelin hydrate 10.1
Mudanpi 9.8
Maxipost 9.8
Dioscorea rhizome 9.8
Rehmannia root 9.5
Bv2 8.6
Fluvoxamine maleate 8.3
Dexibuprofen 8.2
Acthar 8.2
SR 57746A 7.9
Scopolamine 7.8
Donepezil 7.8
Hoelen 7.7
Magnolia bark 7.6
Fluvoxamine maleate 7.6
Cinnamon bark 7.5
Minocin 7.3
Adenosine Monophosphate 7.2
Reminyl 7.1
Flurothyl 7.1
Piracetam 7.1
Exelon 7.0
Nilvadipine 6.9
Vinpocetine 6.9
Ambien 6.8
Idebenone 6.8
Exelon 6.7
Eszopiclone 6.6
Ziconotide 6.6
Aricept 6.4
Hydergine 6.3
Safflower 6.2
Triazolam 6.0
Ceruletide 6.0
Sonata 5.9
Narcan 5.9
Ramelteon 5.8
Monosodium glutamate 5.8
Perindopril 5.7
Moclobemide 5.6
Agomelatine 5.6
Insulin glargine 5.5
Zonisamide 5.5
Cetrorelix 5.5
Coconut oil 5.4
Liraglutide 5.3
Ulinastatin 5.3
Morphine sulfate 5.3
Sesamol 5.3
Escitalopram 5.2
Modafinil 5.1
Roflumilast 5.1
Roflumilast 5.1
Cilostazol 5.0
DPE 5.0
Flurazepam 5.0
Vitamin K2 4.9
Interferon beta 4.9
Fipronil 4.8
Pilocarpine 4.8
Nadolol 4.7
Podophyllum 4.7
Frontal 4.7
Vardenafil 4.7
Quisqualate 4.6
Flunitrazepam 4.6
Ginseng 4.6
Tibolone 4.6
Medetomidine 4.4
Poloxamer 4.4
Atomoxetine 4.4
Propofol 4.4
Aminoguanidine 4.4
Kainic acid 4.4
Aztec 4.3
Sinemet 4.3
THA 4.3
Spiegel 4.2
Ginger 4.2
more...
Enzyme
proprotein convertase 2 8.3
ABA2 6.6
glutaminyl cyclase 6.4
SDMT 6.3
insulin-degrading enzyme 5.9
choline acetyltransferase 5.9
acetylcholinesterase 5.8
neuropsin 5.8
neuropsin 5.5
cholinesterase 5.2
beta-secretase 5.1
HOA 5.1
CaMKII 5.1
GSK 5.1
arginine decarboxylase 5.0
SpeB 5.0
serine racemase 4.9
STK 4.9
arginine decarboxylase 4.8
prolyl endopeptidase 4.8
glycine N-methyltransferase 4.8
type 1 protein phosphatase 4.7
NMT 4.7
lysine acetyltransferase 4.6
NQO2 4.5
Lod 4.5
methionine synthase reductase 4.4
glutathione peroxidase 4.4
glutaryl-CoA dehydrogenase 4.3
monoacylglycerol lipase 4.3
eEF2 kinase 4.2
TMT 4.1
superoxide dismutase 4.1
DAT 3.9
caspase-3 3.9
PCP 3.8
Lys4 3.7
FPS 3.7
methylenetetrahydrofolate reductase 3.6
tryptophan hydroxylase 3.6
methylenetetrahydrofolate reductase 3.6
gamma-glutamylcysteine synthetase 3.6
PDE 3.6
nicotinamide phosphoribosyltransferase 3.6
protein phosphatase 2A 3.5
catalase 3.5
Thy1 3.4
CDR 3.4
tryptophan 2,3-dioxygenase 3.3
delta-aminolevulinic acid dehydratase 3.3
AMP-activated kinase 3.2
cathepsin S 3.1
O-GlcNAc transferase 3.1
PKG 3.1
monoamine oxidase 3.1
NOS 3.1
carbonyl reductase 3.1
calcineurin 3.0
SPT 3.0
isopeptidase 3.0
myrosinase 2.9
protein kinase 2.9
CD10 2.9
cysteine synthase 2.8
caspase-1 2.8
factor C 2.8
PRE 2.8
GTP cyclohydrolase I 2.7
NAT 2.7
phosphodiesterase 2.7
CPM 2.7
caspase-9 2.7
mu-calpain 2.7
tyrosine hydroxylase 2.6
E-2 2.6
glutamate decarboxylase 2.6
SST 2.5
caspase-2 2.5
mitogen-activated protein kinase 2.5
CFI 2.5
more...
Compound
Pratensein 9.8
Agroclavine 9.8
phenyl dihydrogen phosphate 9.8
Manninotriose 9.8
3,21-dihydroxypregnan-20-one 9.5
C7H14 8.9
Senegenin 8.8
Taraxerol 8.6
Taraxerol 8.6
Schisantherin A 8.6
Schisantherin A 8.6
Diisodecyl phthalate 8.3
Biflorin 8.3
Withanolide 8.2
Donepezil hydrochloride 8.1
Gallein 8.0
[1,1'-biphenyl]-4-carboxylic acid 8.0
Gallein 7.9
Decursinol 7.8
Tetrahydropalmatine 7.8
Glycidoxypropyltrimethoxysilane 7.7
Solanesol 7.6
Dicyclomine 7.5
Sakuranetin 7.5
Echinacoside 7.5
Clorazepate 7.3
HFr 7.3
3-hydroxypregnan-20-one 7.2
diphenylarsinic acid 7.2
Nobiletin 7.2
Propiverine 7.1
Trihexyphenidyl 7.1
Sinapic acid 7.1
Zaleplon 7.1
Memantine 7.1
3-hydroxypregnan-20-one 7.1
Rhynchophylline 7.0
Rivastigmine 7.0
Protopine 7.0
Minocycline hydrochloride 6.9
3-pyridinol 6.9
Bisphenol AF 6.9
SEE 6.9
Embelin 6.9
AFMK 6.8
Sevoflurane 6.8
Cuprizone 6.8
Pinocembrin 6.8
Linopirdine 6.8
Pinoresinol 6.7
Domoic acid 6.7
Quetiapine 6.7
Pyrithiamine 6.6
p-Chloroamphetamine 6.4
Erucic acid 6.4
9H-xanthen-9-one 6.4
Arbutin 6.4
1-methyltryptophan 6.4
Angiotensin IV 6.3
Ethyl pyruvate 6.3
Maltol 6.2
Mecamylamine 6.2
Pregnenolone sulfate 6.2
Harmine 6.2
L-chicoric acid 6.2
Rutaecarpine 6.1
Eriodictyol 6.1
threonate 6.1
Rutaecarpine 6.1
Benztropine 6.1
Methyllycaconitine 6.1
Loganin 6.1
1-heptene 6.0
Bergapten 6.0
Naringin 6.0
Arecoline 6.0
Polydatin 6.0
Magnolol 6.0
Salvinorin A 6.0
Tropisetron 5.9
more...