Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0233794 (memory impairment)
7,237 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein CA1 438 Sep 434 acetylcholinesterase 320 brain-derived neurotrophic factor 269 Mol 260 amyloid precursor protein 249 MRI 216 superoxide dismutase 187 TNF 167 GSH 157 CA3 155 caspase-3 144 lipopolysaccharide 126 catalase 126 NMDA receptor 125 Mem 120 APP 119 insulin 117 amyloid beta 108 glutathione peroxidase 103 glial fibrillary acidic protein 98 GABA 96 CREB 87 cytokine 84 tumor necrosis factor 84 choline acetyltransferase 83 olfactory 83 Bcl-2 82 PS1 82 tau protein 76 IL-6 75 synaptophysin 68 inducible nitric oxide synthase 59 axonal 53 GSK 49 BACE1 49 AChE 48 muscarinic receptor 47 histone 47 PSD-95 45 ROS 45 SOD 45 She 42 ATP 42 ERK 42 apolipoprotein E 40 CB1 39 glutamate receptor 38 neurotrophic factor 38 rat) 37 ERK1 37 DCX 36 cAMP response element-binding protein 35 IL-10 32 NR2B 32 AKT 32 mTOR 32 presenilin 1 31 MAPK 31 Nrf2 30 PKA 30 p65 30 nerve growth factor 30 extracellular signal-regulated kinase 30 WMS 30 LPS 29 mouse) 29 CaMKII 29 nitric oxide synthase 29 TLR4 29 neurotrophin 28 phosphodiesterase 28 PI3K 28 gut 28 calmodulin 28 nicotinic acetylcholine receptor 27 ATPase 27 histone deacetylase 27 interleukin-6 27 COX-2 27 more...

Disease memory impairment 7237 Alzheimer's disease 2036 cognitive impairment 1234 dementia 941 depression 497 amnesia 345 epilepsy 257 schizophrenia 251 Parkinson's disease 177 GSH 157 stroke 147 ischemia 130 diabetes 128 cognitive deficit 112 temporal lobe epilepsy 108 cerebral ischemia 107 encephalitis 91 psychosis 91 plaque 88 multiple sclerosis 88 forgetting 76 posttraumatic stress disorder 71 confusion 70 obesity 66 disorientation 66 major depressive disorder 64 retrograde amnesia 60 hallucinations 60 hypertension 58 cancer 58 aphasia 56 brain atrophy 53 encephalopathy 52 anterograde amnesia 50 tumor 48 status epilepticus 48 mental illness 45 apraxia 43 fits 40 type 2 diabetes 39 brain dysfunction 39 Huntington's disease 38 delusions 37 parkinsonism 35 Korsakoff's syndrome 35 HIV 33 hyperglycemia 32 amnesic syndrome 32 memory disorder 32 autism 31 Williams syndrome 31 Evans 31 Down syndrome 31 WMS 30 WMS 30 neuroblastoma 28 aggression 28 chronic pain 27 transient global amnesia 27 amyotrophic lateral sclerosis 26 hydrocephalus 26 senile dementia 26 alcoholism 25 delirium 24 sleep disorders 24 meningitis 24 bipolar disorder 23 NAME 22 cognitive disorder 21 sleep disturbances 21 vascular disease 20 mental retardation 20 AIDS 20 hypothyroidism 20 coma 20 glioma 19 addiction 19 anhedonia 18 sepsis 18 mental retardation 18 more...

Symptom seizures 283 memory loss 234 pain 94 anesthesia 87 headache 70 insomnia 69 fatigue 60 sleepiness 37 agitation 36 ataxia 34 weakness 33 apathy 29 tremor 28 analgesia 26 functional recovery 24 forgetfulness 24 dizziness 22 hypothermia 20 vomiting 18 acute stress 18 personality change 16 nausea 15 myoclonus 14 dysarthria 13 bradykinesia 13 anorexia 13 distraction 13 incoordination 12 thinning 11 diarrhea 11 vertigo 10 abnormal gait 9 dystonia 9 cerebellar ataxia 8 paraparesis 7 Psychiatric symptoms 7 arthralgia 7 catatonia 6 collapse 6 hypersomnia 6 paresis 6 constipation 6 blackout 6 Depressive symptoms 6 lethargy 5 despair 5 spasticity 5 tinnitus 5 hypercapnia 5 myalgia 5 cough 5 hemiplegia 5 stigma 5 numbness 4 chorea 4 overweight 4 Neuropathic pain 4 hangover 3 fasciculation 3 ataxic gait 3 hyperemesis gravidarum 3 neurological disability 3 clumsiness 3 paresthesia 3 muscle rigidity 3 nausea and vomiting 3 Behavioral symptoms 3 orofacial pain 2 consciousness disturbance 2 lightheadedness 2 abdominal pain 2 night sweats 2 discomfort 2 blurred vision 2 chest pain 2 Rebound insomnia 2 feeling depressed 2 visual hallucination 2 Gastrointestinal symptoms 2 exhaustion 2 more...

Drug Scopolamine 67 ROS 45 caffeine 33 Donepezil 27 CSF 24 Ethanol 17 lysine 12 Spectrum 12 Frontal 12 PCP 12 Piracetam 11 Propofol 10 Ginseng 9 ascorbate 9 Portal 8 p75 8 Leaf 8 vitamin E 7 Vitamin E 4 Zonisamide 4 DHT 4 Liraglutide 4 Bifidobacterium 4 Simvastatin 4 Vinpocetine 4 TTC 4 THA 4 Glutathione 4 ALA 4 9-THC 4 Perindopril 4 Triazolam 4 FAD 4 Clonidine 4 Monit 4 DHT 4 Estrogens 4 Pilocarpine 4 Modafinil 3 Parkin 3 Kainic acid 3 Histamine 3 Cilostazol 3 Parkin 3 Cardiovasc 3 Reserpine 3 TMS 3 Atropine 3 Phenytoin 3 EPA 3 Idebenone 3 Asn 3 Rosiglitazone 3 ROC 3 TAK 3 Agomelatine 2 Aminoguanidine 2 IL-1ra 2 IL-2 2 Moclobemide 2 Flunitrazepam 2 Heme 2 Angiotensin II 2 Safflower 2 Monosodium glutamate 2 Fipronil 2 Phosphatidylserine 2 Hydergine 2 G-CSF 2 EE2 2 Fluorescein 2 NVP 2 Cetrorelix 2 DEX 2 Nilvadipine 2 TAC 2 Asthma 2 Vitamin A 2 Ziconotide 2 Methylene blue 2 more...

Enzyme acetylcholinesterase 367 superoxide dismutase 222 catalase 142 protein kinase 142 mitogen-activated protein kinase 123 caspase-3 118 cholinesterase 105 glutathione peroxidase 103 choline acetyltransferase 84 GSK 52 ERK 50 protein kinase C 45 calcineurin 32 CaMKII 31 ATPase 29 phosphodiesterase 28 monoamine oxidase 21 tyrosine hydroxylase 21 CD10 17 PARP 16 AMP-activated protein kinase 15 proteasome 14 NOS 14 ACE 13 ACS 13 peroxidase 13 PCP 12 glutathione reductase 12 MEK 11 AMPK 11 caspase-9 11 caspase-1 10 insulin-degrading enzyme 10 focal adhesion kinase 10 PDE 10 lactate dehydrogenase 9 NADPH oxidase 8 protein phosphatase 2A 8 NADPH oxidase 8 cytochrome oxidase 8 creatine kinase 8 AMPK 7 beta-secretase 7 reverse transcriptase 7 NO synthase 7 phospholipase A2 7 complex I 6 methylenetetrahydrofolate reductase 6 glutathione S-transferase 6 CDR 6 adenosine deaminase 6 adenosine deaminase 6 luciferase 6 methylenetetrahydrofolate reductase 6 alanine aminotransferase 5 tissue plasminogen activator 5 phosphoinositide 3-kinase 5 renin 5 prolyl endopeptidase 5 PKG 5 DAT 5 glutamine synthetase 5 tryptophan hydroxylase 5 succinate dehydrogenase 5 aspartate aminotransferase 4 gamma-glutamylcysteine synthetase 4 arginine decarboxylase 4 cathepsin B 4 arginine decarboxylase 4 heme oxygenase 3 5'-nucleotidase 3 TMT 3 PRE 3 NQO1 3 CYP3A4 3 pyruvate dehydrogenase 3 P-glycoprotein 3 glutamate decarboxylase 3 glutamate dehydrogenase 3 Thy1 3 more...

Compound water 1182 Dec 437 Clin 385 glutamate 189 oxygen 171 TNF 167 glucose 166 GSH 158 GSH 158 ethanol 133 calcium 114 nitric oxide 97 DNA 97 GABA 96 GABA 96 NMDA 85 cAMP 78 galactose 75 5-HT 74 SEE 68 sodium 66 DSM 43 ATP 42 AMPA 40 MDA 39 Neuronal 39 arginine 39 GSSG 36 His 34 caffeine 33 STZ 31 potassium 29 aluminum 29 hydrogen 29 tyrosine 28 leucine 28 gamma-aminobutyric acid 27 Cereb 26 tryptophan 25 AMP 25 iron 25 noradrenaline 24 threonine 24 serine 24 phosphate 24 Insulin 23 methionine 23 acetate 23 Nicotine 23 tryptophan 23 dUTP 22 tryptophan 22 tryptophan 22 Melatonin 21 homocysteine 21 ACh 20 zinc 20 CO2 20 Memantine 19 CAT 19 cGMP 19 Sevoflurane 18 fluorine 18 CAT 18 CAT 18 copper 17 Ketamine 17 lysine 15 bromide 14 Curcumin 14 nicotinamide 14 aspartic acid 13 H2S 13 ACS 13 ACS 13 nitrate 12 MPTP 12 Quetiapine 12 Estrogen 12 pyridine 12 more...

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