Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0233794 (memory impairment)
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Human Gene/Protein
GHBR 11.1
LanC-like protein 2 11.1
V-set and transmembrane domain containing 2 like 11.1
SPON1 protein 11.1
AAK1 protein 11.1
regulator of G-protein signaling 14 10.1
Beta-site APP-cleaving enzyme 10.1
Vsm-RhoGEF 10.1
hRFI 9.8
GABARAP protein 9.8
GMIP 9.6
Tau-tubulin kinase 9.3
paraspeckle protein 1 9.3
PS23 9.1
GMFB 9.1
septin 5 9.1
PTGFRN 9.1
QRFP receptor 9.1
DSCR3 9.1
calcium/calmodulin-dependent protein kinase II alpha 9.0
SPPL2c 8.9
CREB1 protein 8.9
LGI3 8.9
FAST kinase 8.9
ATP5H 8.9
kallikrein 8 8.8
advanced glycosylation end product-specific receptor 8.8
APMAP 8.8
AP2A2 8.8
QN1 8.6
GALM 8.6
CYH 8.5
stromal interaction molecule 2 8.5
Ran-binding protein 9 8.4
TMEM59 8.4
FASTKD2 8.3
calmodulin-like skin protein 8.3
voltage gated potassium channel 8.3
TTC3 8.2
WLT 8.2
more...
Disease
Septum pellucidum cyst 12.1
memory impairment 12.1
hyperleucine-isoleucinemia 12.1
CNS inflammation or infection 12.1
presbyophrenia 10.8
Bradyphrenia 10.5
hypervalinemia 9.8
Transient epileptic amnesia 9.6
moria 9.5
Age-associated memory impairment 9.5
Paranoid delusions 9.5
Confabulation 9.4
Alzheimer's disease with early onset 9.3
Limbic encephalitis 9.2
Classic polyarteritis nodosa 9.1
Constructional apraxia 9.1
alcoholic Korsakoff's syndrome 9.1
memory disorder 8.9
eccentric personality 8.8
loosening of associations 8.8
MCPH6 8.8
amnesic syndrome 8.7
Postoperative cognitive dysfunction 8.5
Cerebral hypoperfusion 8.5
absent-mindedness 8.5
disturbed memory 8.4
retrograde amnesia 8.3
anterograde amnesia 8.3
unable to remember 8.3
WMS 8.2
WMS 8.2
psychogenic amnesia 8.1
Post-traumatic amnesia 8.1
amnesia 8.1
GTP cyclohydrolase I deficiency 8.1
circumstantiality 8.0
perceptual disturbance 8.0
transient global amnesia 7.9
adult hypothyroidism 7.9
Korsakoff's syndrome 7.9
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Symptom
Rebound insomnia 8.6
amimia 8.2
memory loss 8.2
Drop attacks 7.5
Behavioral symptoms 7.3
Multiple symptoms 7.3
forgetfulness 7.3
personality change 7.0
Prodrome 6.7
feeling depressed 6.6
Psychiatric symptoms 6.6
blackout 5.8
elevated mood 5.4
bewilderment 5.3
hangover 5.2
aphonia 5.2
abnormal gait 5.1
photopsia 5.0
apathy 5.0
visual hallucination 4.9
incoordination 4.9
insomnia 4.8
hypersomnia 4.7
Spastic 4.6
bradykinesia 4.6
clumsiness 4.6
Poor sleep 4.6
jaw pain 4.6
hyperemesis gravidarum 4.6
ataxic gait 4.6
catatonia 4.6
adipsia 4.6
loss of taste 4.6
impaired motor coordination 4.5
disturbed balance 4.3
metamorphopsia 4.2
physical symptom 4.2
acute stress 4.1
lightheadedness 4.1
seizures 4.0
more...
Drug
Indeloxazine hydrochloride 10.5
Taltirelin hydrate 10.1
Maxipost 9.8
Mudanpi 9.8
Dioscorea rhizome 9.8
Rehmannia root 9.5
Bv2 8.6
Fluvoxamine maleate 8.3
Acthar 8.2
Dexibuprofen 8.2
SR 57746A 7.9
Scopolamine 7.8
Donepezil 7.8
Hoelen 7.7
Fluvoxamine maleate 7.6
Magnolia bark 7.6
Cinnamon bark 7.5
Minocin 7.3
Adenosine Monophosphate 7.2
Flurothyl 7.1
Reminyl 7.1
Piracetam 7.1
Exelon 7.0
Nilvadipine 6.9
Vinpocetine 6.9
Ambien 6.8
Idebenone 6.8
Exelon 6.7
Eszopiclone 6.6
Ziconotide 6.6
Aricept 6.4
Hydergine 6.3
Safflower 6.2
Triazolam 6.0
Ceruletide 6.0
Sonata 5.9
Narcan 5.9
Ramelteon 5.8
Monosodium glutamate 5.8
Perindopril 5.7
more...
Enzyme
proprotein convertase 2 8.3
ABA2 6.6
glutaminyl cyclase 6.4
SDMT 6.3
insulin-degrading enzyme 5.9
choline acetyltransferase 5.9
acetylcholinesterase 5.8
neuropsin 5.8
neuropsin 5.5
cholinesterase 5.2
beta-secretase 5.1
HOA 5.1
CaMKII 5.1
GSK 5.1
arginine decarboxylase 5.0
SpeB 5.0
serine racemase 4.9
STK 4.9
arginine decarboxylase 4.8
prolyl endopeptidase 4.8
glycine N-methyltransferase 4.8
type 1 protein phosphatase 4.7
NMT 4.7
lysine acetyltransferase 4.6
NQO2 4.5
Lod 4.5
methionine synthase reductase 4.4
glutathione peroxidase 4.4
glutaryl-CoA dehydrogenase 4.3
monoacylglycerol lipase 4.3
eEF2 kinase 4.2
TMT 4.1
superoxide dismutase 4.1
DAT 3.9
caspase-3 3.9
PCP 3.8
Lys4 3.7
FPS 3.7
methylenetetrahydrofolate reductase 3.6
tryptophan hydroxylase 3.6
more...
Compound
phenyl dihydrogen phosphate 9.8
Pratensein 9.8
Manninotriose 9.8
Agroclavine 9.8
3,21-dihydroxypregnan-20-one 9.5
C7H14 8.9
Senegenin 8.8
Taraxerol 8.6
Taraxerol 8.6
Schisantherin A 8.6
Schisantherin A 8.6
Diisodecyl phthalate 8.3
Biflorin 8.3
Withanolide 8.2
Donepezil hydrochloride 8.1
[1,1'-biphenyl]-4-carboxylic acid 8.0
Gallein 8.0
Gallein 7.9
Decursinol 7.8
Tetrahydropalmatine 7.8
Glycidoxypropyltrimethoxysilane 7.7
Solanesol 7.6
Dicyclomine 7.5
Sakuranetin 7.5
Echinacoside 7.5
Clorazepate 7.3
HFr 7.3
3-hydroxypregnan-20-one 7.2
diphenylarsinic acid 7.2
Nobiletin 7.2
Propiverine 7.1
Sinapic acid 7.1
Zaleplon 7.1
Trihexyphenidyl 7.1
Memantine 7.1
3-hydroxypregnan-20-one 7.1
Rhynchophylline 7.0
Rivastigmine 7.0
Protopine 7.0
Bisphenol AF 6.9
more...