Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0233794 (
memory impairment
)
7,237
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
CA1
438
Sep
434
acetylcholinesterase
320
brain-derived neurotrophic factor
269
Mol
260
amyloid precursor protein
249
MRI
216
superoxide dismutase
187
TNF
167
GSH
157
CA3
155
caspase-3
144
lipopolysaccharide
126
catalase
126
NMDA receptor
125
Mem
120
APP
119
insulin
117
amyloid beta
108
glutathione peroxidase
103
glial fibrillary acidic protein
98
GABA
96
CREB
87
tumor necrosis factor
84
cytokine
84
choline acetyltransferase
83
olfactory
83
PS1
82
Bcl-2
82
tau protein
76
IL-6
75
synaptophysin
68
inducible nitric oxide synthase
59
axonal
53
GSK
49
BACE1
49
AChE
48
muscarinic receptor
47
histone
47
SOD
45
more...
Disease
memory impairment
7237
Alzheimer's disease
2036
cognitive impairment
1234
dementia
941
depression
497
amnesia
345
epilepsy
257
schizophrenia
251
Parkinson's disease
177
GSH
157
stroke
147
ischemia
130
diabetes
128
cognitive deficit
112
temporal lobe epilepsy
108
cerebral ischemia
107
psychosis
91
encephalitis
91
plaque
88
multiple sclerosis
88
forgetting
76
posttraumatic stress disorder
71
confusion
70
disorientation
66
obesity
66
major depressive disorder
64
hallucinations
60
retrograde amnesia
60
cancer
58
hypertension
58
aphasia
56
brain atrophy
53
encephalopathy
52
anterograde amnesia
50
tumor
48
status epilepticus
48
mental illness
45
apraxia
43
fits
40
type 2 diabetes
39
more...
Symptom
seizures
283
memory loss
234
pain
94
anesthesia
87
headache
70
insomnia
69
fatigue
60
sleepiness
37
agitation
36
ataxia
34
weakness
33
apathy
29
tremor
28
analgesia
26
functional recovery
24
forgetfulness
24
dizziness
22
hypothermia
20
vomiting
18
acute stress
18
personality change
16
nausea
15
myoclonus
14
bradykinesia
13
anorexia
13
dysarthria
13
distraction
13
incoordination
12
thinning
11
diarrhea
11
vertigo
10
dystonia
9
abnormal gait
9
cerebellar ataxia
8
arthralgia
7
paraparesis
7
Psychiatric symptoms
7
Depressive symptoms
6
blackout
6
constipation
6
more...
Drug
Scopolamine
67
ROS
45
caffeine
33
Donepezil
27
CSF
24
Ethanol
17
Frontal
12
lysine
12
Spectrum
12
PCP
12
Piracetam
11
Propofol
10
Ginseng
9
ascorbate
9
Leaf
8
p75
8
Portal
8
vitamin E
7
Estrogens
4
Bifidobacterium
4
THA
4
DHT
4
Pilocarpine
4
Clonidine
4
Triazolam
4
Liraglutide
4
TTC
4
Vinpocetine
4
ALA
4
FAD
4
Zonisamide
4
Perindopril
4
DHT
4
Simvastatin
4
Glutathione
4
Monit
4
Vitamin E
4
9-THC
4
Parkin
3
TMS
3
more...
Enzyme
acetylcholinesterase
367
superoxide dismutase
222
protein kinase
142
catalase
142
mitogen-activated protein kinase
123
caspase-3
118
cholinesterase
105
glutathione peroxidase
103
choline acetyltransferase
84
GSK
52
ERK
50
protein kinase C
45
calcineurin
32
CaMKII
31
ATPase
29
phosphodiesterase
28
tyrosine hydroxylase
21
monoamine oxidase
21
CD10
17
PARP
16
AMP-activated protein kinase
15
proteasome
14
NOS
14
ACS
13
ACE
13
peroxidase
13
glutathione reductase
12
PCP
12
caspase-9
11
AMPK
11
MEK
11
PDE
10
insulin-degrading enzyme
10
caspase-1
10
focal adhesion kinase
10
lactate dehydrogenase
9
protein phosphatase 2A
8
NADPH oxidase
8
NADPH oxidase
8
cytochrome oxidase
8
more...
Compound
water
1182
Dec
437
Clin
385
glutamate
189
oxygen
171
TNF
167
glucose
166
GSH
158
GSH
158
ethanol
133
calcium
114
nitric oxide
97
DNA
97
GABA
96
GABA
96
NMDA
85
cAMP
78
galactose
75
5-HT
74
SEE
68
sodium
66
DSM
43
ATP
42
AMPA
40
Neuronal
39
arginine
39
MDA
39
GSSG
36
His
34
caffeine
33
STZ
31
aluminum
29
hydrogen
29
potassium
29
tyrosine
28
leucine
28
gamma-aminobutyric acid
27
Cereb
26
tryptophan
25
AMP
25
more...